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Cloning of a novel glutamate receptor subunit, GluR5

Standard

Cloning of a novel glutamate receptor subunit, GluR5 : expression in the nervous system during development. / Bettler, B; Boulter, J; Hermans-Borgmeyer, I; O'Shea-Greenfield, A; Deneris, E S; Moll, C; Borgmeyer, U; Hollmann, M; Heinemann, S.

in: NEURON, Jahrgang 5, Nr. 5, 11.1990, S. 583-95.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Bettler, B, Boulter, J, Hermans-Borgmeyer, I, O'Shea-Greenfield, A, Deneris, ES, Moll, C, Borgmeyer, U, Hollmann, M & Heinemann, S 1990, 'Cloning of a novel glutamate receptor subunit, GluR5: expression in the nervous system during development', NEURON, Jg. 5, Nr. 5, S. 583-95.

APA

Bettler, B., Boulter, J., Hermans-Borgmeyer, I., O'Shea-Greenfield, A., Deneris, E. S., Moll, C., Borgmeyer, U., Hollmann, M., & Heinemann, S. (1990). Cloning of a novel glutamate receptor subunit, GluR5: expression in the nervous system during development. NEURON, 5(5), 583-95.

Vancouver

Bettler B, Boulter J, Hermans-Borgmeyer I, O'Shea-Greenfield A, Deneris ES, Moll C et al. Cloning of a novel glutamate receptor subunit, GluR5: expression in the nervous system during development. NEURON. 1990 Nov;5(5):583-95.

Bibtex

@article{141260d00b4e4d7bb94cc68904a0e3a2,
title = "Cloning of a novel glutamate receptor subunit, GluR5: expression in the nervous system during development",
abstract = "We have isolated cDNAs encoding a glutamate receptor subunit, designated GluR5, displaying 40%-41% amino acid identity with the kainate/AMPA receptor subunits GluR1, GluR2, GluR3, and GluR4. This level of sequence similarity is significantly below the approximately 70% intersubunit identity characteristic of kainate/AMPA receptors. The GluR5 protein forms homomeric ion channels in Xenopus oocytes that are weakly responsive to L-glutamate. The GluR5 gene is expressed in subsets of neurons throughout the developing and adult central and peripheral nervous systems. During embryogenesis, GluR5 transcripts are detected in areas of neuronal differentiation and synapse formation.",
keywords = "Aging, Animals, Base Sequence, Central Nervous System, Cloning, Molecular, Gene Expression Regulation, Genes, Glutamates, Glutamic Acid, In Vitro Techniques, Oocytes, Peripheral Nerves, Receptors, Glutamate, Receptors, Neurotransmitter, Xenopus",
author = "B Bettler and J Boulter and I Hermans-Borgmeyer and A O'Shea-Greenfield and Deneris, {E S} and C Moll and U Borgmeyer and M Hollmann and S Heinemann",
year = "1990",
month = nov,
language = "English",
volume = "5",
pages = "583--95",
journal = "NEURON",
issn = "0896-6273",
publisher = "Cell Press",
number = "5",

}

RIS

TY - JOUR

T1 - Cloning of a novel glutamate receptor subunit, GluR5

T2 - expression in the nervous system during development

AU - Bettler, B

AU - Boulter, J

AU - Hermans-Borgmeyer, I

AU - O'Shea-Greenfield, A

AU - Deneris, E S

AU - Moll, C

AU - Borgmeyer, U

AU - Hollmann, M

AU - Heinemann, S

PY - 1990/11

Y1 - 1990/11

N2 - We have isolated cDNAs encoding a glutamate receptor subunit, designated GluR5, displaying 40%-41% amino acid identity with the kainate/AMPA receptor subunits GluR1, GluR2, GluR3, and GluR4. This level of sequence similarity is significantly below the approximately 70% intersubunit identity characteristic of kainate/AMPA receptors. The GluR5 protein forms homomeric ion channels in Xenopus oocytes that are weakly responsive to L-glutamate. The GluR5 gene is expressed in subsets of neurons throughout the developing and adult central and peripheral nervous systems. During embryogenesis, GluR5 transcripts are detected in areas of neuronal differentiation and synapse formation.

AB - We have isolated cDNAs encoding a glutamate receptor subunit, designated GluR5, displaying 40%-41% amino acid identity with the kainate/AMPA receptor subunits GluR1, GluR2, GluR3, and GluR4. This level of sequence similarity is significantly below the approximately 70% intersubunit identity characteristic of kainate/AMPA receptors. The GluR5 protein forms homomeric ion channels in Xenopus oocytes that are weakly responsive to L-glutamate. The GluR5 gene is expressed in subsets of neurons throughout the developing and adult central and peripheral nervous systems. During embryogenesis, GluR5 transcripts are detected in areas of neuronal differentiation and synapse formation.

KW - Aging

KW - Animals

KW - Base Sequence

KW - Central Nervous System

KW - Cloning, Molecular

KW - Gene Expression Regulation

KW - Genes

KW - Glutamates

KW - Glutamic Acid

KW - In Vitro Techniques

KW - Oocytes

KW - Peripheral Nerves

KW - Receptors, Glutamate

KW - Receptors, Neurotransmitter

KW - Xenopus

M3 - SCORING: Journal article

C2 - 1977421

VL - 5

SP - 583

EP - 595

JO - NEURON

JF - NEURON

SN - 0896-6273

IS - 5

ER -