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Claudication, in contrast to angina pectoris, independently predicts mortality risk in the general population

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Claudication, in contrast to angina pectoris, independently predicts mortality risk in the general population. / Kieback, Arne G; Lorbeer, Roberto; Wallaschofski, Henri; Ittermann, Till; Völzke, Henry; Felix, Stephan; Dörr, Marcus.

in: VASA, Jahrgang 41, Nr. 2, 03.2012, S. 105-113.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Kieback, AG, Lorbeer, R, Wallaschofski, H, Ittermann, T, Völzke, H, Felix, S & Dörr, M 2012, 'Claudication, in contrast to angina pectoris, independently predicts mortality risk in the general population', VASA, Jg. 41, Nr. 2, S. 105-113. https://doi.org/10.1024/0301-1526/a000172

APA

Kieback, A. G., Lorbeer, R., Wallaschofski, H., Ittermann, T., Völzke, H., Felix, S., & Dörr, M. (2012). Claudication, in contrast to angina pectoris, independently predicts mortality risk in the general population. VASA, 41(2), 105-113. https://doi.org/10.1024/0301-1526/a000172

Vancouver

Kieback AG, Lorbeer R, Wallaschofski H, Ittermann T, Völzke H, Felix S et al. Claudication, in contrast to angina pectoris, independently predicts mortality risk in the general population. VASA. 2012 Mär;41(2):105-113. https://doi.org/10.1024/0301-1526/a000172

Bibtex

@article{aa8611dde5c94bbe8e495c523db60753,
title = "Claudication, in contrast to angina pectoris, independently predicts mortality risk in the general population",
abstract = "BACKGROUND: The aim of our analyses was to investigate whether claudication and angina pectoris, each defined and based on the answer to a single question, are predictive of future mortality.PROBANDS AND METHODS: The study population consisted of 3995 subjects selected from the population-based Study of Health In Pomerania (SHIP). Kaplan-Meier analysis and multivariable Cox proportional hazards regression analysis were used to analyze the association of angina pectoris and claudication with all-cause and cardiovascular mortality adjusted for major cardiovascular risk factors.RESULTS: At baseline, 417 individuals had symptoms of angina pectoris, and 323 had symptoms of claudication. During a median follow-up of 8.5 years, 277 individuals died. Individuals with claudication had a higher fully-adjusted all-cause mortality rate (Hazard Ratio (HR) 1.79; 95 % CI 1.34, 2.39, p < 0.001) and a higher sex- and age-adjusted cardiovascular mortality rate (HR 1.76; 95 % CI 1.03, 2.99, p = 0.038) compared to subjects without claudication. In contrast, subjects with angina pectoris had neither an elevated fully-adjusted all-cause mortality rate (HR 1.15; 95 % CI 0.82, 1.61, p = 0.413) nor sex- and age-adjusted cardiovascular mortality rate (HR 0.71; 95 % CI 0.34, 1.48, p = 0.363) compared to those without this symptom.CONCLUSIONS: Claudication, in contrast to angina pectoris, is a strong, independent predictor of all-cause mortality.",
keywords = "Adult, Aged, Angina Pectoris/mortality, Female, Germany/epidemiology, Health Surveys, Humans, Intermittent Claudication/mortality, Kaplan-Meier Estimate, Male, Middle Aged, Multivariate Analysis, Prognosis, Proportional Hazards Models, Risk Assessment, Risk Factors, Surveys and Questionnaires, Time Factors",
author = "Kieback, {Arne G} and Roberto Lorbeer and Henri Wallaschofski and Till Ittermann and Henry V{\"o}lzke and Stephan Felix and Marcus D{\"o}rr",
year = "2012",
month = mar,
doi = "10.1024/0301-1526/a000172",
language = "English",
volume = "41",
pages = "105--113",
journal = "VASA",
issn = "0301-1526",
publisher = "Hans Huber",
number = "2",

}

RIS

TY - JOUR

T1 - Claudication, in contrast to angina pectoris, independently predicts mortality risk in the general population

AU - Kieback, Arne G

AU - Lorbeer, Roberto

AU - Wallaschofski, Henri

AU - Ittermann, Till

AU - Völzke, Henry

AU - Felix, Stephan

AU - Dörr, Marcus

PY - 2012/3

Y1 - 2012/3

N2 - BACKGROUND: The aim of our analyses was to investigate whether claudication and angina pectoris, each defined and based on the answer to a single question, are predictive of future mortality.PROBANDS AND METHODS: The study population consisted of 3995 subjects selected from the population-based Study of Health In Pomerania (SHIP). Kaplan-Meier analysis and multivariable Cox proportional hazards regression analysis were used to analyze the association of angina pectoris and claudication with all-cause and cardiovascular mortality adjusted for major cardiovascular risk factors.RESULTS: At baseline, 417 individuals had symptoms of angina pectoris, and 323 had symptoms of claudication. During a median follow-up of 8.5 years, 277 individuals died. Individuals with claudication had a higher fully-adjusted all-cause mortality rate (Hazard Ratio (HR) 1.79; 95 % CI 1.34, 2.39, p < 0.001) and a higher sex- and age-adjusted cardiovascular mortality rate (HR 1.76; 95 % CI 1.03, 2.99, p = 0.038) compared to subjects without claudication. In contrast, subjects with angina pectoris had neither an elevated fully-adjusted all-cause mortality rate (HR 1.15; 95 % CI 0.82, 1.61, p = 0.413) nor sex- and age-adjusted cardiovascular mortality rate (HR 0.71; 95 % CI 0.34, 1.48, p = 0.363) compared to those without this symptom.CONCLUSIONS: Claudication, in contrast to angina pectoris, is a strong, independent predictor of all-cause mortality.

AB - BACKGROUND: The aim of our analyses was to investigate whether claudication and angina pectoris, each defined and based on the answer to a single question, are predictive of future mortality.PROBANDS AND METHODS: The study population consisted of 3995 subjects selected from the population-based Study of Health In Pomerania (SHIP). Kaplan-Meier analysis and multivariable Cox proportional hazards regression analysis were used to analyze the association of angina pectoris and claudication with all-cause and cardiovascular mortality adjusted for major cardiovascular risk factors.RESULTS: At baseline, 417 individuals had symptoms of angina pectoris, and 323 had symptoms of claudication. During a median follow-up of 8.5 years, 277 individuals died. Individuals with claudication had a higher fully-adjusted all-cause mortality rate (Hazard Ratio (HR) 1.79; 95 % CI 1.34, 2.39, p < 0.001) and a higher sex- and age-adjusted cardiovascular mortality rate (HR 1.76; 95 % CI 1.03, 2.99, p = 0.038) compared to subjects without claudication. In contrast, subjects with angina pectoris had neither an elevated fully-adjusted all-cause mortality rate (HR 1.15; 95 % CI 0.82, 1.61, p = 0.413) nor sex- and age-adjusted cardiovascular mortality rate (HR 0.71; 95 % CI 0.34, 1.48, p = 0.363) compared to those without this symptom.CONCLUSIONS: Claudication, in contrast to angina pectoris, is a strong, independent predictor of all-cause mortality.

KW - Adult

KW - Aged

KW - Angina Pectoris/mortality

KW - Female

KW - Germany/epidemiology

KW - Health Surveys

KW - Humans

KW - Intermittent Claudication/mortality

KW - Kaplan-Meier Estimate

KW - Male

KW - Middle Aged

KW - Multivariate Analysis

KW - Prognosis

KW - Proportional Hazards Models

KW - Risk Assessment

KW - Risk Factors

KW - Surveys and Questionnaires

KW - Time Factors

U2 - 10.1024/0301-1526/a000172

DO - 10.1024/0301-1526/a000172

M3 - SCORING: Journal article

C2 - 22403128

VL - 41

SP - 105

EP - 113

JO - VASA

JF - VASA

SN - 0301-1526

IS - 2

ER -