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Circulating nucleic acids as biomarkers in breast cancer

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Circulating nucleic acids as biomarkers in breast cancer. / Schwarzenbach, Heidi.

in: BREAST CANCER RES, Jahrgang 15, Nr. 5, 01.01.2013, S. 211.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Schwarzenbach, H 2013, 'Circulating nucleic acids as biomarkers in breast cancer', BREAST CANCER RES, Jg. 15, Nr. 5, S. 211. https://doi.org/10.1186/bcr3446

APA

Schwarzenbach, H. (2013). Circulating nucleic acids as biomarkers in breast cancer. BREAST CANCER RES, 15(5), 211. https://doi.org/10.1186/bcr3446

Vancouver

Schwarzenbach H. Circulating nucleic acids as biomarkers in breast cancer. BREAST CANCER RES. 2013 Jan 1;15(5):211. https://doi.org/10.1186/bcr3446

Bibtex

@article{f7c8c182dc9149a18e855eac9469006f,
title = "Circulating nucleic acids as biomarkers in breast cancer",
abstract = "During tumor development, tumor cells release their nucleic acids into the blood circulation. This process occurs by apoptotic and necrotic cell deaths along with active cell secretion, resulting in high levels of circulating DNA, mRNA, and microRNA in the blood of patients with breast cancer. As circulating cell-free tumor nucleic acids may reflect the characteristics of the primary tumor and even of micrometastatic cells, they may be excellent blood biomarkers for screening breast cancer. Assays that allow the repetitive monitoring of patients by using blood samples as liquid biopsy may be efficient in assessing cancer progression in patients whose tumor tissue is not available. This review evaluates the recent data on the potential use of circulating cell-free nucleic acids as biomarkers for breast cancer.",
author = "Heidi Schwarzenbach",
year = "2013",
month = jan,
day = "1",
doi = "10.1186/bcr3446",
language = "English",
volume = "15",
pages = "211",
journal = "BREAST CANCER RES",
issn = "1465-5411",
publisher = "BioMed Central Ltd.",
number = "5",

}

RIS

TY - JOUR

T1 - Circulating nucleic acids as biomarkers in breast cancer

AU - Schwarzenbach, Heidi

PY - 2013/1/1

Y1 - 2013/1/1

N2 - During tumor development, tumor cells release their nucleic acids into the blood circulation. This process occurs by apoptotic and necrotic cell deaths along with active cell secretion, resulting in high levels of circulating DNA, mRNA, and microRNA in the blood of patients with breast cancer. As circulating cell-free tumor nucleic acids may reflect the characteristics of the primary tumor and even of micrometastatic cells, they may be excellent blood biomarkers for screening breast cancer. Assays that allow the repetitive monitoring of patients by using blood samples as liquid biopsy may be efficient in assessing cancer progression in patients whose tumor tissue is not available. This review evaluates the recent data on the potential use of circulating cell-free nucleic acids as biomarkers for breast cancer.

AB - During tumor development, tumor cells release their nucleic acids into the blood circulation. This process occurs by apoptotic and necrotic cell deaths along with active cell secretion, resulting in high levels of circulating DNA, mRNA, and microRNA in the blood of patients with breast cancer. As circulating cell-free tumor nucleic acids may reflect the characteristics of the primary tumor and even of micrometastatic cells, they may be excellent blood biomarkers for screening breast cancer. Assays that allow the repetitive monitoring of patients by using blood samples as liquid biopsy may be efficient in assessing cancer progression in patients whose tumor tissue is not available. This review evaluates the recent data on the potential use of circulating cell-free nucleic acids as biomarkers for breast cancer.

U2 - 10.1186/bcr3446

DO - 10.1186/bcr3446

M3 - SCORING: Journal article

C2 - 24090167

VL - 15

SP - 211

JO - BREAST CANCER RES

JF - BREAST CANCER RES

SN - 1465-5411

IS - 5

ER -