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Cell-free nucleic acids as biomarkers in cancer patients.

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Cell-free nucleic acids as biomarkers in cancer patients. / Schwarzenbach, Heidi; Hoon, Dave S B; Pantel, Klaus.

in: NAT REV CANCER, Jahrgang 11, Nr. 6, 6, 2011, S. 426-437.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Schwarzenbach, H, Hoon, DSB & Pantel, K 2011, 'Cell-free nucleic acids as biomarkers in cancer patients.', NAT REV CANCER, Jg. 11, Nr. 6, 6, S. 426-437. <http://www.ncbi.nlm.nih.gov/pubmed/21562580?dopt=Citation>

APA

Schwarzenbach, H., Hoon, D. S. B., & Pantel, K. (2011). Cell-free nucleic acids as biomarkers in cancer patients. NAT REV CANCER, 11(6), 426-437. [6]. http://www.ncbi.nlm.nih.gov/pubmed/21562580?dopt=Citation

Vancouver

Schwarzenbach H, Hoon DSB, Pantel K. Cell-free nucleic acids as biomarkers in cancer patients. NAT REV CANCER. 2011;11(6):426-437. 6.

Bibtex

@article{d8f45cb172234850b36884df31c68c2e,
title = "Cell-free nucleic acids as biomarkers in cancer patients.",
abstract = "DNA, mRNA and microRNA are released and circulate in the blood of cancer patients. Changes in the levels of circulating nucleic acids have been associated with tumour burden and malignant progression. In the past decade a wealth of information indicating the potential use of circulating nucleic acids for cancer screening, prognosis and monitoring of the efficacy of anticancer therapies has emerged. In this Review, we discuss these findings with a specific focus on the clinical utility of cell-free nucleic acids as blood biomarkers.",
keywords = "Humans, Mutation, Apoptosis, DNA/*blood, DNA, Viral/blood, MicroRNAs/*blood, Neoplasms/*blood/genetics, RNA, Messenger/*blood, Tumor Markers, Biological/*blood, Humans, Mutation, Apoptosis, DNA/*blood, DNA, Viral/blood, MicroRNAs/*blood, Neoplasms/*blood/genetics, RNA, Messenger/*blood, Tumor Markers, Biological/*blood",
author = "Heidi Schwarzenbach and Hoon, {Dave S B} and Klaus Pantel",
year = "2011",
language = "English",
volume = "11",
pages = "426--437",
journal = "NAT REV CANCER",
issn = "1474-175X",
publisher = "NATURE PUBLISHING GROUP",
number = "6",

}

RIS

TY - JOUR

T1 - Cell-free nucleic acids as biomarkers in cancer patients.

AU - Schwarzenbach, Heidi

AU - Hoon, Dave S B

AU - Pantel, Klaus

PY - 2011

Y1 - 2011

N2 - DNA, mRNA and microRNA are released and circulate in the blood of cancer patients. Changes in the levels of circulating nucleic acids have been associated with tumour burden and malignant progression. In the past decade a wealth of information indicating the potential use of circulating nucleic acids for cancer screening, prognosis and monitoring of the efficacy of anticancer therapies has emerged. In this Review, we discuss these findings with a specific focus on the clinical utility of cell-free nucleic acids as blood biomarkers.

AB - DNA, mRNA and microRNA are released and circulate in the blood of cancer patients. Changes in the levels of circulating nucleic acids have been associated with tumour burden and malignant progression. In the past decade a wealth of information indicating the potential use of circulating nucleic acids for cancer screening, prognosis and monitoring of the efficacy of anticancer therapies has emerged. In this Review, we discuss these findings with a specific focus on the clinical utility of cell-free nucleic acids as blood biomarkers.

KW - Humans

KW - Mutation

KW - Apoptosis

KW - DNA/blood

KW - DNA, Viral/blood

KW - MicroRNAs/blood

KW - Neoplasms/blood/genetics

KW - RNA, Messenger/blood

KW - Tumor Markers, Biological/blood

KW - Humans

KW - Mutation

KW - Apoptosis

KW - DNA/blood

KW - DNA, Viral/blood

KW - MicroRNAs/blood

KW - Neoplasms/blood/genetics

KW - RNA, Messenger/blood

KW - Tumor Markers, Biological/blood

M3 - SCORING: Journal article

VL - 11

SP - 426

EP - 437

JO - NAT REV CANCER

JF - NAT REV CANCER

SN - 1474-175X

IS - 6

M1 - 6

ER -