Best practices for time-resolved serial synchrotron crystallography

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Best practices for time-resolved serial synchrotron crystallography. / Schulz, Eike C; Yorke, Briony A; Pearson, Arwen R; Mehrabi, Pedram.

in: ACTA CRYSTALLOGR D, Jahrgang 78, Nr. 1, 01.01.2022, S. 14-29.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ReviewForschung

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@article{bac4969432f24406bd910cec402f5f15,
title = "Best practices for time-resolved serial synchrotron crystallography",
abstract = "With recent developments in X-ray sources, instrumentation and data-analysis tools, time-resolved crystallographic experiments, which were originally the preserve of a few expert groups, are becoming simpler and can be carried out at more radiation sources, and are thus increasingly accessible to a growing user base. However, these experiments are just that: discrete experiments, not just `data collections'. As such, careful planning and consideration of potential pitfalls is required to enable a successful experiment. Here, some of the key factors that should be considered during the planning and execution of a time-resolved structural study are outlined, with a particular focus on synchrotron-based experiments.",
keywords = "Animals, Crystallography, X-Ray/instrumentation, Data Analysis, Enzymes/chemistry, Humans, Synchrotrons",
author = "Schulz, {Eike C} and Yorke, {Briony A} and Pearson, {Arwen R} and Pedram Mehrabi",
note = "open access.",
year = "2022",
month = jan,
day = "1",
doi = "10.1107/S2059798321011621",
language = "English",
volume = "78",
pages = "14--29",
journal = "ACTA CRYSTALLOGR D",
issn = "2059-7983",
publisher = "John Wiley and Sons Inc.",
number = "1",

}

RIS

TY - JOUR

T1 - Best practices for time-resolved serial synchrotron crystallography

AU - Schulz, Eike C

AU - Yorke, Briony A

AU - Pearson, Arwen R

AU - Mehrabi, Pedram

N1 - open access.

PY - 2022/1/1

Y1 - 2022/1/1

N2 - With recent developments in X-ray sources, instrumentation and data-analysis tools, time-resolved crystallographic experiments, which were originally the preserve of a few expert groups, are becoming simpler and can be carried out at more radiation sources, and are thus increasingly accessible to a growing user base. However, these experiments are just that: discrete experiments, not just `data collections'. As such, careful planning and consideration of potential pitfalls is required to enable a successful experiment. Here, some of the key factors that should be considered during the planning and execution of a time-resolved structural study are outlined, with a particular focus on synchrotron-based experiments.

AB - With recent developments in X-ray sources, instrumentation and data-analysis tools, time-resolved crystallographic experiments, which were originally the preserve of a few expert groups, are becoming simpler and can be carried out at more radiation sources, and are thus increasingly accessible to a growing user base. However, these experiments are just that: discrete experiments, not just `data collections'. As such, careful planning and consideration of potential pitfalls is required to enable a successful experiment. Here, some of the key factors that should be considered during the planning and execution of a time-resolved structural study are outlined, with a particular focus on synchrotron-based experiments.

KW - Animals

KW - Crystallography, X-Ray/instrumentation

KW - Data Analysis

KW - Enzymes/chemistry

KW - Humans

KW - Synchrotrons

U2 - 10.1107/S2059798321011621

DO - 10.1107/S2059798321011621

M3 - SCORING: Review article

C2 - 34981758

VL - 78

SP - 14

EP - 29

JO - ACTA CRYSTALLOGR D

JF - ACTA CRYSTALLOGR D

SN - 2059-7983

IS - 1

ER -