Antibody prevalence to the 2009 pandemic influenza A (H1N1) virus in Germany: geographically variable immunity in winter 2010/2011

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Antibody prevalence to the 2009 pandemic influenza A (H1N1) virus in Germany: geographically variable immunity in winter 2010/2011. / Hackenberg, Anne; Arman-Kalcek, Gökhan; Hiller, Jens; Gabriel, Gülsah.

in: Medical microbiology and immunology, Jahrgang 202, Nr. 1, 01.02.2013, S. 87-94.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

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@article{9219499ec3134bf18a5c17d31dc43134,
title = "Antibody prevalence to the 2009 pandemic influenza A (H1N1) virus in Germany: geographically variable immunity in winter 2010/2011",
abstract = "Location- and age-specific prevalence of antibodies against 2009 pandemic influenza A (H1N1) virus were determined in sera of blood donors collected during winter 2010/2011 in Germany. Prevalence of antibodies at protective titres (HI ≥1:40) varied significantly between cities (24.13-83.67 %) throughout all age groups. However, high level antibodies (HI >1:80) were most prevalent among young individuals (18-29 and 30-39 years). Overall, this study demonstrates that older people (50-59 and 60-70 years) are no longer more likely to present protective antibody titres against 2009 pandemic influenza A (H1N1) virus than younger individuals. Furthermore, our data show a highly variable immunity among the German population in different major cities almost 2 years after the detection of first cases in Germany.",
keywords = "Adolescent, Adult, Age Factors, Aged, Antibodies, Viral, Female, Germany, Humans, Influenza A Virus, H1N1 Subtype, Influenza, Human, Male, Middle Aged, Seroepidemiologic Studies, Young Adult",
author = "Anne Hackenberg and G{\"o}khan Arman-Kalcek and Jens Hiller and G{\"u}lsah Gabriel",
year = "2013",
month = feb,
day = "1",
doi = "10.1007/s00430-012-0251-4",
language = "English",
volume = "202",
pages = "87--94",
journal = "MED MICROBIOL IMMUN",
issn = "0300-8584",
publisher = "Springer",
number = "1",

}

RIS

TY - JOUR

T1 - Antibody prevalence to the 2009 pandemic influenza A (H1N1) virus in Germany: geographically variable immunity in winter 2010/2011

AU - Hackenberg, Anne

AU - Arman-Kalcek, Gökhan

AU - Hiller, Jens

AU - Gabriel, Gülsah

PY - 2013/2/1

Y1 - 2013/2/1

N2 - Location- and age-specific prevalence of antibodies against 2009 pandemic influenza A (H1N1) virus were determined in sera of blood donors collected during winter 2010/2011 in Germany. Prevalence of antibodies at protective titres (HI ≥1:40) varied significantly between cities (24.13-83.67 %) throughout all age groups. However, high level antibodies (HI >1:80) were most prevalent among young individuals (18-29 and 30-39 years). Overall, this study demonstrates that older people (50-59 and 60-70 years) are no longer more likely to present protective antibody titres against 2009 pandemic influenza A (H1N1) virus than younger individuals. Furthermore, our data show a highly variable immunity among the German population in different major cities almost 2 years after the detection of first cases in Germany.

AB - Location- and age-specific prevalence of antibodies against 2009 pandemic influenza A (H1N1) virus were determined in sera of blood donors collected during winter 2010/2011 in Germany. Prevalence of antibodies at protective titres (HI ≥1:40) varied significantly between cities (24.13-83.67 %) throughout all age groups. However, high level antibodies (HI >1:80) were most prevalent among young individuals (18-29 and 30-39 years). Overall, this study demonstrates that older people (50-59 and 60-70 years) are no longer more likely to present protective antibody titres against 2009 pandemic influenza A (H1N1) virus than younger individuals. Furthermore, our data show a highly variable immunity among the German population in different major cities almost 2 years after the detection of first cases in Germany.

KW - Adolescent

KW - Adult

KW - Age Factors

KW - Aged

KW - Antibodies, Viral

KW - Female

KW - Germany

KW - Humans

KW - Influenza A Virus, H1N1 Subtype

KW - Influenza, Human

KW - Male

KW - Middle Aged

KW - Seroepidemiologic Studies

KW - Young Adult

U2 - 10.1007/s00430-012-0251-4

DO - 10.1007/s00430-012-0251-4

M3 - SCORING: Journal article

C2 - 22684725

VL - 202

SP - 87

EP - 94

JO - MED MICROBIOL IMMUN

JF - MED MICROBIOL IMMUN

SN - 0300-8584

IS - 1

ER -