PortalPublikationenAnalysis of pralidoxime in serum, brain and CSF of rats.

Analysis of pralidoxime in serum, brain and CSF of rats.

Standard

Analysis of pralidoxime in serum, brain and CSF of rats. / Kalász, Huba; Szöko, Eva; Tábi, Tamás; Petroianu, Georg A; Lorke, Dietrich; Omar, Abdulrab; Alafifi, Salem; Jasem, Almerri; Tekes, Kornélia.

in: MED CHEM, Jahrgang 5, Nr. 3, 3, 2009, S. 237-241.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Kalász, H, Szöko, E, Tábi, T, Petroianu, GA, Lorke, D, Omar, A, Alafifi, S, Jasem, A & Tekes, K 2009, 'Analysis of pralidoxime in serum, brain and CSF of rats.', MED CHEM, Jg. 5, Nr. 3, 3, S. 237-241. <http://www.ncbi.nlm.nih.gov/pubmed/19442213?dopt=Citation>

APA

Kalász, H., Szöko, E., Tábi, T., Petroianu, G. A., Lorke, D., Omar, A., Alafifi, S., Jasem, A., & Tekes, K. (2009). Analysis of pralidoxime in serum, brain and CSF of rats. MED CHEM, 5(3), 237-241. [3]. http://www.ncbi.nlm.nih.gov/pubmed/19442213?dopt=Citation

Vancouver

Kalász H, Szöko E, Tábi T, Petroianu GA, Lorke D, Omar A et al. Analysis of pralidoxime in serum, brain and CSF of rats. MED CHEM. 2009;5(3):237-241. 3.

Bibtex

@article{8108c412ea504233a406f134b31e7e6c,
title = "Analysis of pralidoxime in serum, brain and CSF of rats.",
abstract = "After administration of various amounts of pralidoxime to rats, the levels in serum, brain and cerebrospinal fluid (CSF) were measured using capillary zone electrophoresis (CZE). The calibration curves were established using spiked samples. The calibration covers the ranges from 0.3 - 200 microg/mL, 0.3 - 7 microg/mL and 0.1 - 7 microg/mL for serum, brain and CSF, respectively. The CZE measurement opens the way to the fast and reliable determination of pyridinium aldoxime concentrations in serum, cerebrospinal fluid and brain, thereby monitoring blood-brain and blood-CSF penetration of pyridinium aldoxime-type antidotes clinically used in organophosphate poisoning.",
author = "Huba Kal{\'a}sz and Eva Sz{\"o}ko and Tam{\'a}s T{\'a}bi and Petroianu, {Georg A} and Dietrich Lorke and Abdulrab Omar and Salem Alafifi and Almerri Jasem and Korn{\'e}lia Tekes",
year = "2009",
language = "Deutsch",
volume = "5",
pages = "237--241",
journal = "MED CHEM",
issn = "1573-4064",
publisher = "Bentham Science Publishers B.V.",
number = "3",

}

RIS

TY - JOUR

T1 - Analysis of pralidoxime in serum, brain and CSF of rats.

AU - Kalász, Huba

AU - Szöko, Eva

AU - Tábi, Tamás

AU - Petroianu, Georg A

AU - Lorke, Dietrich

AU - Omar, Abdulrab

AU - Alafifi, Salem

AU - Jasem, Almerri

AU - Tekes, Kornélia

PY - 2009

Y1 - 2009

N2 - After administration of various amounts of pralidoxime to rats, the levels in serum, brain and cerebrospinal fluid (CSF) were measured using capillary zone electrophoresis (CZE). The calibration curves were established using spiked samples. The calibration covers the ranges from 0.3 - 200 microg/mL, 0.3 - 7 microg/mL and 0.1 - 7 microg/mL for serum, brain and CSF, respectively. The CZE measurement opens the way to the fast and reliable determination of pyridinium aldoxime concentrations in serum, cerebrospinal fluid and brain, thereby monitoring blood-brain and blood-CSF penetration of pyridinium aldoxime-type antidotes clinically used in organophosphate poisoning.

AB - After administration of various amounts of pralidoxime to rats, the levels in serum, brain and cerebrospinal fluid (CSF) were measured using capillary zone electrophoresis (CZE). The calibration curves were established using spiked samples. The calibration covers the ranges from 0.3 - 200 microg/mL, 0.3 - 7 microg/mL and 0.1 - 7 microg/mL for serum, brain and CSF, respectively. The CZE measurement opens the way to the fast and reliable determination of pyridinium aldoxime concentrations in serum, cerebrospinal fluid and brain, thereby monitoring blood-brain and blood-CSF penetration of pyridinium aldoxime-type antidotes clinically used in organophosphate poisoning.

M3 - SCORING: Zeitschriftenaufsatz

VL - 5

SP - 237

EP - 241

JO - MED CHEM

JF - MED CHEM

SN - 1573-4064

IS - 3

M1 - 3

ER -