Alcoholic ingredients in skin disinfectants increase biofilm expression of Staphylococcus epidermidis.

Standard

Alcoholic ingredients in skin disinfectants increase biofilm expression of Staphylococcus epidermidis. / Knobloch, Johannes K-M; Horstkotte, Matthias A; Rohde, Holger; Kaulfers, Paul-Michael; Mack, Dietrich.

in: J ANTIMICROB CHEMOTH, Jahrgang 49, Nr. 4, 4, 2002, S. 683-687.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

Harvard

APA

Vancouver

Bibtex

@article{b469c9dc7c29412e9b006f6bfea3c708,
title = "Alcoholic ingredients in skin disinfectants increase biofilm expression of Staphylococcus epidermidis.",
abstract = "The pathogenesis of Staphylococcus epidermidis is correlated with biofilm formation. We investigated the effect of three common alcoholic skin disinfectants, ethanol, n-propanol and isopropanol, on the biofilm formation of 37 clinical, icaADBC-positive S. epidermidis isolates. In alcohol-supplemented media 18 strains displayed increased biofilm expression. Sixteen of 19 strains were generally incapable of biofilm formation. In three representative isolates, the increase in biofilm formation was paralleled by increased polysaccharide intercellular adhesin synthesis. Regarding the widespread use of alcoholic skin disinfectants, it is possible that the alcohol-inducible biofilm phenotype of S. epidermidis could add to the development of foreign body-related infections.",
author = "Knobloch, {Johannes K-M} and Horstkotte, {Matthias A} and Holger Rohde and Paul-Michael Kaulfers and Dietrich Mack",
year = "2002",
doi = "10.1093/jac/49.4.683",
language = "Deutsch",
volume = "49",
pages = "683--687",
journal = "J ANTIMICROB CHEMOTH",
issn = "0305-7453",
publisher = "Oxford University Press",
number = "4",

}

RIS

TY - JOUR

T1 - Alcoholic ingredients in skin disinfectants increase biofilm expression of Staphylococcus epidermidis.

AU - Knobloch, Johannes K-M

AU - Horstkotte, Matthias A

AU - Rohde, Holger

AU - Kaulfers, Paul-Michael

AU - Mack, Dietrich

PY - 2002

Y1 - 2002

N2 - The pathogenesis of Staphylococcus epidermidis is correlated with biofilm formation. We investigated the effect of three common alcoholic skin disinfectants, ethanol, n-propanol and isopropanol, on the biofilm formation of 37 clinical, icaADBC-positive S. epidermidis isolates. In alcohol-supplemented media 18 strains displayed increased biofilm expression. Sixteen of 19 strains were generally incapable of biofilm formation. In three representative isolates, the increase in biofilm formation was paralleled by increased polysaccharide intercellular adhesin synthesis. Regarding the widespread use of alcoholic skin disinfectants, it is possible that the alcohol-inducible biofilm phenotype of S. epidermidis could add to the development of foreign body-related infections.

AB - The pathogenesis of Staphylococcus epidermidis is correlated with biofilm formation. We investigated the effect of three common alcoholic skin disinfectants, ethanol, n-propanol and isopropanol, on the biofilm formation of 37 clinical, icaADBC-positive S. epidermidis isolates. In alcohol-supplemented media 18 strains displayed increased biofilm expression. Sixteen of 19 strains were generally incapable of biofilm formation. In three representative isolates, the increase in biofilm formation was paralleled by increased polysaccharide intercellular adhesin synthesis. Regarding the widespread use of alcoholic skin disinfectants, it is possible that the alcohol-inducible biofilm phenotype of S. epidermidis could add to the development of foreign body-related infections.

U2 - 10.1093/jac/49.4.683

DO - 10.1093/jac/49.4.683

M3 - SCORING: Zeitschriftenaufsatz

VL - 49

SP - 683

EP - 687

JO - J ANTIMICROB CHEMOTH

JF - J ANTIMICROB CHEMOTH

SN - 0305-7453

IS - 4

M1 - 4

ER -