Actomyosin Contractility in the Generation and Plasticity of Axons and Dendritic Spines

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Actomyosin Contractility in the Generation and Plasticity of Axons and Dendritic Spines. / Mikhaylova, Marina; Rentsch, Jakob; Ewers, Helge.

in: CELLS-BASEL, Jahrgang 9, Nr. 9, 01.09.2020.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ReviewForschung

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@article{247a2229157743058dc9776d75c2560a,
title = "Actomyosin Contractility in the Generation and Plasticity of Axons and Dendritic Spines",
abstract = "Actin and non-muscle myosins have long been known to play important roles in growth cone steering and neurite outgrowth. More recently, novel functions for non-muscle myosin have been described in axons and dendritic spines. Consequently, possible roles of actomyosin contraction in organizing and maintaining structural properties of dendritic spines, the size and location of axon initial segment and axonal diameter are emerging research topics. In this review, we aim to summarize recent findings involving myosin localization and function in these compartments and to discuss possible roles for actomyosin in their function and the signaling pathways that control them.",
author = "Marina Mikhaylova and Jakob Rentsch and Helge Ewers",
year = "2020",
month = sep,
day = "1",
doi = "10.3390/cells9092006",
language = "English",
volume = "9",
journal = "CELLS-BASEL",
issn = "2073-4409",
publisher = "MDPI Multidisciplinary Digital Publishing Institute",
number = "9",

}

RIS

TY - JOUR

T1 - Actomyosin Contractility in the Generation and Plasticity of Axons and Dendritic Spines

AU - Mikhaylova, Marina

AU - Rentsch, Jakob

AU - Ewers, Helge

PY - 2020/9/1

Y1 - 2020/9/1

N2 - Actin and non-muscle myosins have long been known to play important roles in growth cone steering and neurite outgrowth. More recently, novel functions for non-muscle myosin have been described in axons and dendritic spines. Consequently, possible roles of actomyosin contraction in organizing and maintaining structural properties of dendritic spines, the size and location of axon initial segment and axonal diameter are emerging research topics. In this review, we aim to summarize recent findings involving myosin localization and function in these compartments and to discuss possible roles for actomyosin in their function and the signaling pathways that control them.

AB - Actin and non-muscle myosins have long been known to play important roles in growth cone steering and neurite outgrowth. More recently, novel functions for non-muscle myosin have been described in axons and dendritic spines. Consequently, possible roles of actomyosin contraction in organizing and maintaining structural properties of dendritic spines, the size and location of axon initial segment and axonal diameter are emerging research topics. In this review, we aim to summarize recent findings involving myosin localization and function in these compartments and to discuss possible roles for actomyosin in their function and the signaling pathways that control them.

U2 - 10.3390/cells9092006

DO - 10.3390/cells9092006

M3 - SCORING: Review article

C2 - 32882840

VL - 9

JO - CELLS-BASEL

JF - CELLS-BASEL

SN - 2073-4409

IS - 9

ER -