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Activity modulation of the bacterial Rho GAP YopE: an inspiration for the investigation of mammalian Rho GAPs.

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Activity modulation of the bacterial Rho GAP YopE: an inspiration for the investigation of mammalian Rho GAPs. / Aepfelbacher, Martin; Roppenser, Bernhard; Hentschke, Moritz; Ruckdeschel, Klaus.

in: EUR J CELL BIOL, Jahrgang 90, Nr. 11, 11, 2011, S. 951-954.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Aepfelbacher, M, Roppenser, B, Hentschke, M & Ruckdeschel, K 2011, 'Activity modulation of the bacterial Rho GAP YopE: an inspiration for the investigation of mammalian Rho GAPs.', EUR J CELL BIOL, Jg. 90, Nr. 11, 11, S. 951-954. <http://www.ncbi.nlm.nih.gov/pubmed/21255863?dopt=Citation>

APA

Aepfelbacher, M., Roppenser, B., Hentschke, M., & Ruckdeschel, K. (2011). Activity modulation of the bacterial Rho GAP YopE: an inspiration for the investigation of mammalian Rho GAPs. EUR J CELL BIOL, 90(11), 951-954. [11]. http://www.ncbi.nlm.nih.gov/pubmed/21255863?dopt=Citation

Vancouver

Aepfelbacher M, Roppenser B, Hentschke M, Ruckdeschel K. Activity modulation of the bacterial Rho GAP YopE: an inspiration for the investigation of mammalian Rho GAPs. EUR J CELL BIOL. 2011;90(11):951-954. 11.

Bibtex

@article{9b7b081da99d438cba135ac915770a4c,
title = "Activity modulation of the bacterial Rho GAP YopE: an inspiration for the investigation of mammalian Rho GAPs.",
abstract = "The Yersinia enterocolitica Rho GTPase Activating Protein (Rho GAP) YopE belongs to a group of bacterial virulence factors that is translocated into infected target cells by a type three secretion system. Structurally and biochemically YopE resembles eukaryotic Rho GAPs which control various cellular functions by modulating the activity of Rho GTP binding proteins. Here we summarise the published information on cellular effects, Rho protein substrates, compartmentalisation and turnover of YopE. A fascinating picture evolves of how this virulence factor integrates in host cellular regulatory mechanisms to fine tune bacterial pathogenicity.",
keywords = "Animals, Humans, Ubiquitination, Bacterial Outer Membrane Proteins/chemistry/*metabolism, Bacterial Toxins/metabolism, GTPase-Activating Proteins/chemistry/*metabolism, Yersinia enterocolitica/*metabolism, rho GTP-Binding Proteins/*metabolism, Animals, Humans, Ubiquitination, Bacterial Outer Membrane Proteins/chemistry/*metabolism, Bacterial Toxins/metabolism, GTPase-Activating Proteins/chemistry/*metabolism, Yersinia enterocolitica/*metabolism, rho GTP-Binding Proteins/*metabolism",
author = "Martin Aepfelbacher and Bernhard Roppenser and Moritz Hentschke and Klaus Ruckdeschel",
year = "2011",
language = "English",
volume = "90",
pages = "951--954",
journal = "EUR J CELL BIOL",
issn = "0171-9335",
publisher = "Urban und Fischer Verlag GmbH und Co. KG",
number = "11",

}

RIS

TY - JOUR

T1 - Activity modulation of the bacterial Rho GAP YopE: an inspiration for the investigation of mammalian Rho GAPs.

AU - Aepfelbacher, Martin

AU - Roppenser, Bernhard

AU - Hentschke, Moritz

AU - Ruckdeschel, Klaus

PY - 2011

Y1 - 2011

N2 - The Yersinia enterocolitica Rho GTPase Activating Protein (Rho GAP) YopE belongs to a group of bacterial virulence factors that is translocated into infected target cells by a type three secretion system. Structurally and biochemically YopE resembles eukaryotic Rho GAPs which control various cellular functions by modulating the activity of Rho GTP binding proteins. Here we summarise the published information on cellular effects, Rho protein substrates, compartmentalisation and turnover of YopE. A fascinating picture evolves of how this virulence factor integrates in host cellular regulatory mechanisms to fine tune bacterial pathogenicity.

AB - The Yersinia enterocolitica Rho GTPase Activating Protein (Rho GAP) YopE belongs to a group of bacterial virulence factors that is translocated into infected target cells by a type three secretion system. Structurally and biochemically YopE resembles eukaryotic Rho GAPs which control various cellular functions by modulating the activity of Rho GTP binding proteins. Here we summarise the published information on cellular effects, Rho protein substrates, compartmentalisation and turnover of YopE. A fascinating picture evolves of how this virulence factor integrates in host cellular regulatory mechanisms to fine tune bacterial pathogenicity.

KW - Animals

KW - Humans

KW - Ubiquitination

KW - Bacterial Outer Membrane Proteins/chemistry/metabolism

KW - Bacterial Toxins/metabolism

KW - GTPase-Activating Proteins/chemistry/metabolism

KW - Yersinia enterocolitica/metabolism

KW - rho GTP-Binding Proteins/metabolism

KW - Animals

KW - Humans

KW - Ubiquitination

KW - Bacterial Outer Membrane Proteins/chemistry/metabolism

KW - Bacterial Toxins/metabolism

KW - GTPase-Activating Proteins/chemistry/metabolism

KW - Yersinia enterocolitica/metabolism

KW - rho GTP-Binding Proteins/metabolism

M3 - SCORING: Journal article

VL - 90

SP - 951

EP - 954

JO - EUR J CELL BIOL

JF - EUR J CELL BIOL

SN - 0171-9335

IS - 11

M1 - 11

ER -