Active cortical dendrites modulate perception

Naoya Takahashi; Thomas G Oertner; Peter Hegemann; Matthew E Larkum

doi:10.1126/science.aah6066

Active cortical dendrites modulate perception

Standard

Active cortical dendrites modulate perception. / Takahashi, Naoya; Oertner, Thomas G; Hegemann, Peter; Larkum, Matthew E.

in: SCIENCE, Jahrgang 354, Nr. 6319, 23.12.2016, S. 1587-1590.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Takahashi, N, Oertner, TG, Hegemann, P & Larkum, ME 2016, 'Active cortical dendrites modulate perception', SCIENCE, Jg. 354, Nr. 6319, S. 1587-1590. https://doi.org/10.1126/science.aah6066

APA

Takahashi, N., Oertner, T. G., Hegemann, P., & Larkum, M. E. (2016). Active cortical dendrites modulate perception. SCIENCE, 354(6319), 1587-1590. https://doi.org/10.1126/science.aah6066

Vancouver

Takahashi N, Oertner TG, Hegemann P, Larkum ME. Active cortical dendrites modulate perception. SCIENCE. 2016 Dez 23;354(6319):1587-1590. https://doi.org/10.1126/science.aah6066

Bibtex

@article{287c16ca673d41d9ba57c05df5446fd6,

title = "Active cortical dendrites modulate perception",

abstract = "There is as yet no consensus concerning the neural basis of perception and how it operates at a mechanistic level. We found that Ca(2+) activity in the apical dendrites of a subset of layer 5 (L5) pyramidal neurons in primary somatosensory cortex (S1) in mice is correlated with the threshold for perceptual detection of whisker deflections. Manipulating the activity of apical dendrites shifted the perceptual threshold, demonstrating that an active dendritic mechanism is causally linked to perceptual detection.",

author = "Naoya Takahashi and Oertner, {Thomas G} and Peter Hegemann and Larkum, {Matthew E}",

note = "Copyright {\textcopyright} 2016, American Association for the Advancement of Science.",

year = "2016",

month = dec,

day = "23",

doi = "10.1126/science.aah6066",

language = "English",

volume = "354",

pages = "1587--1590",

journal = "SCIENCE",

issn = "0036-8075",

publisher = "American Association for the Advancement of Science",

number = "6319",

}

RIS

TY - JOUR

T1 - Active cortical dendrites modulate perception

AU - Takahashi, Naoya

AU - Oertner, Thomas G

AU - Hegemann, Peter

AU - Larkum, Matthew E

PY - 2016/12/23

Y1 - 2016/12/23

N2 - There is as yet no consensus concerning the neural basis of perception and how it operates at a mechanistic level. We found that Ca(2+) activity in the apical dendrites of a subset of layer 5 (L5) pyramidal neurons in primary somatosensory cortex (S1) in mice is correlated with the threshold for perceptual detection of whisker deflections. Manipulating the activity of apical dendrites shifted the perceptual threshold, demonstrating that an active dendritic mechanism is causally linked to perceptual detection.

AB - There is as yet no consensus concerning the neural basis of perception and how it operates at a mechanistic level. We found that Ca(2+) activity in the apical dendrites of a subset of layer 5 (L5) pyramidal neurons in primary somatosensory cortex (S1) in mice is correlated with the threshold for perceptual detection of whisker deflections. Manipulating the activity of apical dendrites shifted the perceptual threshold, demonstrating that an active dendritic mechanism is causally linked to perceptual detection.

U2 - 10.1126/science.aah6066

DO - 10.1126/science.aah6066

M3 - SCORING: Journal article

C2 - 28008068

VL - 354

SP - 1587

EP - 1590

JO - SCIENCE

JF - SCIENCE

SN - 0036-8075

IS - 6319

ER -