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A track of the clones: new developments in cellular barcoding

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A track of the clones: new developments in cellular barcoding. / Lyne, Anne-Marie; Kent, David G; Laurenti, Elisa; Cornils, Kerstin; Glauche, Ingmar; Perié, Leïla.

in: EXP HEMATOL, Jahrgang 68, 12.2018, S. 15-20.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Review › Forschung

Harvard

Lyne, A-M, Kent, DG, Laurenti, E, Cornils, K, Glauche, I & Perié, L 2018, 'A track of the clones: new developments in cellular barcoding', EXP HEMATOL, Jg. 68, S. 15-20. https://doi.org/10.1016/j.exphem.2018.11.005

APA

Lyne, A-M., Kent, D. G., Laurenti, E., Cornils, K., Glauche, I., & Perié, L. (2018). A track of the clones: new developments in cellular barcoding. EXP HEMATOL, 68, 15-20. https://doi.org/10.1016/j.exphem.2018.11.005

Vancouver

Lyne A-M, Kent DG, Laurenti E, Cornils K, Glauche I, Perié L. A track of the clones: new developments in cellular barcoding. EXP HEMATOL. 2018 Dez;68:15-20. https://doi.org/10.1016/j.exphem.2018.11.005

Bibtex

@article{10d4ad1fc31c458b823d481964357f7c,
title = "A track of the clones: new developments in cellular barcoding",
abstract = "International experts from multiple disciplines gathered at Homerton College in Cambridge, UK from September 12-14, 2018 to consider recent advances and emerging opportunities in the clonal tracking of hematopoiesis in one of a series of StemCellMathLab workshops. The group included 35 participants with experience in the fields of theoretical and experimental aspects of clonal tracking, and ranged from doctoral students to senior professors. Data from a variety of model systems and from clinical gene therapy trials were discussed, along with strategies for data analysis and sharing and challenges arising due to underlying assumptions in data interpretation and communication. Recognizing the power of this technology underpinned a group consensus of a need for improved mechanisms for sharing data and analytical protocols to maintain reproducibility and rigor in its application to complex tissues.",
keywords = "Journal Article, Review, Genetic Therapy, DNA Barcoding, Taxonomic/methods, Guidelines as Topic, Reproducibility of Results, Clinical Trials as Topic, Data Display/standards, Genetic Markers, Forecasting, DNA Transposable Elements, Virus Integration/genetics, Cell Lineage, Clone Cells/cytology, Hematopoiesis, Models, Biological, Cell Tracking/methods, Mosaicism, Cell Separation/methods, Research Design, Stem Cells/cytology",
author = "Anne-Marie Lyne and Kent, {David G} and Elisa Laurenti and Kerstin Cornils and Ingmar Glauche and Le{\"i}la Peri{\'e}",
note = "Copyright {\textcopyright} 2018. Published by Elsevier Inc.",
year = "2018",
month = dec,
doi = "10.1016/j.exphem.2018.11.005",
language = "English",
volume = "68",
pages = "15--20",
journal = "EXP HEMATOL",
issn = "0301-472X",
publisher = "Elsevier Inc.",

}

RIS

TY - JOUR

T1 - A track of the clones: new developments in cellular barcoding

AU - Lyne, Anne-Marie

AU - Kent, David G

AU - Laurenti, Elisa

AU - Cornils, Kerstin

AU - Glauche, Ingmar

AU - Perié, Leïla

N1 - Copyright © 2018. Published by Elsevier Inc.

PY - 2018/12

Y1 - 2018/12

N2 - International experts from multiple disciplines gathered at Homerton College in Cambridge, UK from September 12-14, 2018 to consider recent advances and emerging opportunities in the clonal tracking of hematopoiesis in one of a series of StemCellMathLab workshops. The group included 35 participants with experience in the fields of theoretical and experimental aspects of clonal tracking, and ranged from doctoral students to senior professors. Data from a variety of model systems and from clinical gene therapy trials were discussed, along with strategies for data analysis and sharing and challenges arising due to underlying assumptions in data interpretation and communication. Recognizing the power of this technology underpinned a group consensus of a need for improved mechanisms for sharing data and analytical protocols to maintain reproducibility and rigor in its application to complex tissues.

AB - International experts from multiple disciplines gathered at Homerton College in Cambridge, UK from September 12-14, 2018 to consider recent advances and emerging opportunities in the clonal tracking of hematopoiesis in one of a series of StemCellMathLab workshops. The group included 35 participants with experience in the fields of theoretical and experimental aspects of clonal tracking, and ranged from doctoral students to senior professors. Data from a variety of model systems and from clinical gene therapy trials were discussed, along with strategies for data analysis and sharing and challenges arising due to underlying assumptions in data interpretation and communication. Recognizing the power of this technology underpinned a group consensus of a need for improved mechanisms for sharing data and analytical protocols to maintain reproducibility and rigor in its application to complex tissues.

KW - Journal Article

KW - Review

KW - Genetic Therapy

KW - DNA Barcoding, Taxonomic/methods

KW - Guidelines as Topic

KW - Reproducibility of Results

KW - Clinical Trials as Topic

KW - Data Display/standards

KW - Genetic Markers

KW - Forecasting

KW - DNA Transposable Elements

KW - Virus Integration/genetics

KW - Cell Lineage

KW - Clone Cells/cytology

KW - Hematopoiesis

KW - Models, Biological

KW - Cell Tracking/methods

KW - Mosaicism

KW - Cell Separation/methods

KW - Research Design

KW - Stem Cells/cytology

U2 - 10.1016/j.exphem.2018.11.005

DO - 10.1016/j.exphem.2018.11.005

M3 - SCORING: Review article

C2 - 30448259

VL - 68

SP - 15

EP - 20

JO - EXP HEMATOL

JF - EXP HEMATOL

SN - 0301-472X

ER -