A novel workflow for three-dimensional analysis of tumour cell migration
Beteiligte Einrichtungen
Abstract
The limitations of two-dimensional analysis in three-dimensional (3D) cellular imaging impair the accuracy of research findings in biological studies. Here, we report a novel 3D approach to acquisition, analysis and interpretation of tumour spheroid images. Our research interest in mesenchymal-amoeboid transition led to the development of a workflow incorporating the generation and analysis of 3D data with instant structured illumination microscopy and a new ImageJ plugin.
Bibliografische Daten
Originalsprache | Englisch |
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ISSN | 2042-8898 |
DOIs | |
Status | Veröffentlicht - 06.04.2020 |
PubMed | 32194931 |
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