PortalPublikationenA new type of MAML2 fusion in mucoepidermoid carcinoma.

A new type of MAML2 fusion in mucoepidermoid carcinoma.

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A new type of MAML2 fusion in mucoepidermoid carcinoma. / Fehr, André; Röser, Kerstin; Heidorn, Klaus; Hallas, Cora; Löning, Thomas; Bullerdiek, Jörn.

in: GENE CHROMOSOME CANC, Jahrgang 47, Nr. 3, 3, 2008, S. 203-206.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Fehr, A, Röser, K, Heidorn, K, Hallas, C, Löning, T & Bullerdiek, J 2008, 'A new type of MAML2 fusion in mucoepidermoid carcinoma.', GENE CHROMOSOME CANC, Jg. 47, Nr. 3, 3, S. 203-206. <http://www.ncbi.nlm.nih.gov/pubmed/18050304?dopt=Citation>

APA

Fehr, A., Röser, K., Heidorn, K., Hallas, C., Löning, T., & Bullerdiek, J. (2008). A new type of MAML2 fusion in mucoepidermoid carcinoma. GENE CHROMOSOME CANC, 47(3), 203-206. [3]. http://www.ncbi.nlm.nih.gov/pubmed/18050304?dopt=Citation

Vancouver

Fehr A, Röser K, Heidorn K, Hallas C, Löning T, Bullerdiek J. A new type of MAML2 fusion in mucoepidermoid carcinoma. GENE CHROMOSOME CANC. 2008;47(3):203-206. 3.

Bibtex

@article{6730e15297ed4f64adae8ffc7a783c8a,
title = "A new type of MAML2 fusion in mucoepidermoid carcinoma.",
abstract = "The present study reports for the first time a CRTC3-MAML2 fusion gene in a mucoepidermoid carcinoma, as determined by RT-PCR and sequencing. We screened a total of 67 formalin-fixed, paraffin-embedded mucoepidermoid carcinomas for the presence of chimeric genes. In one of these samples, a CRTC3-MAML2 fusion gene was detected. Thus, this report demonstrates the existence of a fusion of MAML2 with CREB regulated transcriptional coactivator CRTC3 additional to the already known fusion of MAML2 and CRTC1. Both gene fusions seem to result in an identical tumor phenotype and the fusion genes CRTC1-MAML2 and CRTC3-MAML2 may play a similar role in the development of mucoepidermoid carcinomas.",
author = "Andr{\'e} Fehr and Kerstin R{\"o}ser and Klaus Heidorn and Cora Hallas and Thomas L{\"o}ning and J{\"o}rn Bullerdiek",
year = "2008",
language = "Deutsch",
volume = "47",
pages = "203--206",
journal = "GENE CHROMOSOME CANC",
issn = "1045-2257",
publisher = "Wiley-Liss Inc.",
number = "3",

}

RIS

TY - JOUR

T1 - A new type of MAML2 fusion in mucoepidermoid carcinoma.

AU - Fehr, André

AU - Röser, Kerstin

AU - Heidorn, Klaus

AU - Hallas, Cora

AU - Löning, Thomas

AU - Bullerdiek, Jörn

PY - 2008

Y1 - 2008

N2 - The present study reports for the first time a CRTC3-MAML2 fusion gene in a mucoepidermoid carcinoma, as determined by RT-PCR and sequencing. We screened a total of 67 formalin-fixed, paraffin-embedded mucoepidermoid carcinomas for the presence of chimeric genes. In one of these samples, a CRTC3-MAML2 fusion gene was detected. Thus, this report demonstrates the existence of a fusion of MAML2 with CREB regulated transcriptional coactivator CRTC3 additional to the already known fusion of MAML2 and CRTC1. Both gene fusions seem to result in an identical tumor phenotype and the fusion genes CRTC1-MAML2 and CRTC3-MAML2 may play a similar role in the development of mucoepidermoid carcinomas.

AB - The present study reports for the first time a CRTC3-MAML2 fusion gene in a mucoepidermoid carcinoma, as determined by RT-PCR and sequencing. We screened a total of 67 formalin-fixed, paraffin-embedded mucoepidermoid carcinomas for the presence of chimeric genes. In one of these samples, a CRTC3-MAML2 fusion gene was detected. Thus, this report demonstrates the existence of a fusion of MAML2 with CREB regulated transcriptional coactivator CRTC3 additional to the already known fusion of MAML2 and CRTC1. Both gene fusions seem to result in an identical tumor phenotype and the fusion genes CRTC1-MAML2 and CRTC3-MAML2 may play a similar role in the development of mucoepidermoid carcinomas.

M3 - SCORING: Zeitschriftenaufsatz

VL - 47

SP - 203

EP - 206

JO - GENE CHROMOSOME CANC

JF - GENE CHROMOSOME CANC

SN - 1045-2257

IS - 3

M1 - 3

ER -