Wachstumsfaktoren zur Vermeidung von Amputation bei gestörter Wundheilung
Standard
Wachstumsfaktoren zur Vermeidung von Amputation bei gestörter Wundheilung. / Debus, E S; Schmidt, K; Geiger, D; Dietz, U A; Thiede, A.
In: Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress, Vol. 118, 2001, p. 829-833.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Wachstumsfaktoren zur Vermeidung von Amputation bei gestörter Wundheilung
AU - Debus, E S
AU - Schmidt, K
AU - Geiger, D
AU - Dietz, U A
AU - Thiede, A
PY - 2001
Y1 - 2001
N2 - Growth factors are mediators with essential importance for undisturbed repair process after wounding. The coordinated concert of these substances is necessary for healing with complete restoration of function and morphology. These complex mechanisms are disturbed during secondary and delayed repair. Local and systemic application of these growth factors seems to add important instruments for therapeutic use in the treatment of chronic wounds. Knowledge from experimental research is encouraging, although the exact mechanisms of synergistic action are not completely understood. However, the results from clinical use in controlled studies do not meet these expectations by far. Leading results from experimental and clinical studies are summarized in detail. Further intensive research however is required for the rational use of growth factors in the clinical setting.
AB - Growth factors are mediators with essential importance for undisturbed repair process after wounding. The coordinated concert of these substances is necessary for healing with complete restoration of function and morphology. These complex mechanisms are disturbed during secondary and delayed repair. Local and systemic application of these growth factors seems to add important instruments for therapeutic use in the treatment of chronic wounds. Knowledge from experimental research is encouraging, although the exact mechanisms of synergistic action are not completely understood. However, the results from clinical use in controlled studies do not meet these expectations by far. Leading results from experimental and clinical studies are summarized in detail. Further intensive research however is required for the rational use of growth factors in the clinical setting.
KW - Amputation
KW - Animals
KW - Complex Mixtures
KW - Growth Substances/therapeutic use
KW - Humans
KW - Randomized Controlled Trials as Topic
KW - Treatment Outcome
KW - Wound Healing/drug effects
M3 - SCORING: Zeitschriftenaufsatz
C2 - 11824370
VL - 118
SP - 829
EP - 833
ER -
