Vorhofflimmern: Wie wichtig ist der Erhalt des Sinusrhythmus?

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Vorhofflimmern: Wie wichtig ist der Erhalt des Sinusrhythmus? / Meyer, Christian; Metzner, Andreas; Kirchhof, Paulus.

In: DEUT MED WOCHENSCHR, Vol. 145, No. 8, 04.2020, p. 543-549.

Research output: SCORING: Contribution to journalSCORING: Review articleResearch

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@article{7bb22f107d8949089559d9975a20be72,
title = "Vorhofflimmern: Wie wichtig ist der Erhalt des Sinusrhythmus?",
abstract = "Rhythm control therapy, comprising antiarrhythmic drugs, cardioversion, and AF ablation, is an important component in the management of patients with atrial fibrillation (AF). Catheter ablation for AF, mainly targeting isolation of the pulmonary veins (AF ablation), has markedly improved the effectiveness of rhythm control therapy. Rhythm control improves symptoms and quality of life in patients with symptomatic AF. AF ablation maintains sinus rhythm more effectively than antiarrhythmic drug therapy. Antiarrhythmic drugs remain effective after AF ablation, underpinning the synergistic mechanisms of action of AF ablation and antiarrhythmic drugs. Different lifestyle interventions might additionally improve symptoms and rhythm stability in patients with AF. AF ablation appears to improve left ventricular function in a subset of patients. Summarized, rhythm control therapy in patients with symptomatic AF is safe and improves quality of life, including elderly patients with stroke risk factors. Further studies are needed to determine whether rhythm control therapy reduces AF-related complications while improving patient outcome with regard to prognosis.",
keywords = "Anti-Arrhythmia Agents/therapeutic use, Atrial Fibrillation/complications, Catheter Ablation, Electric Countershock, Humans, Quality of Life, Stroke/etiology, Ventricular Function, Left/physiology",
author = "Christian Meyer and Andreas Metzner and Paulus Kirchhof",
note = "{\textcopyright} Georg Thieme Verlag KG Stuttgart · New York.",
year = "2020",
month = apr,
doi = "10.1055/a-0969-6352",
language = "Deutsch",
volume = "145",
pages = "543--549",
journal = "DEUT MED WOCHENSCHR",
issn = "0012-0472",
publisher = "Georg Thieme Verlag KG",
number = "8",

}

RIS

TY - JOUR

T1 - Vorhofflimmern: Wie wichtig ist der Erhalt des Sinusrhythmus?

AU - Meyer, Christian

AU - Metzner, Andreas

AU - Kirchhof, Paulus

N1 - © Georg Thieme Verlag KG Stuttgart · New York.

PY - 2020/4

Y1 - 2020/4

N2 - Rhythm control therapy, comprising antiarrhythmic drugs, cardioversion, and AF ablation, is an important component in the management of patients with atrial fibrillation (AF). Catheter ablation for AF, mainly targeting isolation of the pulmonary veins (AF ablation), has markedly improved the effectiveness of rhythm control therapy. Rhythm control improves symptoms and quality of life in patients with symptomatic AF. AF ablation maintains sinus rhythm more effectively than antiarrhythmic drug therapy. Antiarrhythmic drugs remain effective after AF ablation, underpinning the synergistic mechanisms of action of AF ablation and antiarrhythmic drugs. Different lifestyle interventions might additionally improve symptoms and rhythm stability in patients with AF. AF ablation appears to improve left ventricular function in a subset of patients. Summarized, rhythm control therapy in patients with symptomatic AF is safe and improves quality of life, including elderly patients with stroke risk factors. Further studies are needed to determine whether rhythm control therapy reduces AF-related complications while improving patient outcome with regard to prognosis.

AB - Rhythm control therapy, comprising antiarrhythmic drugs, cardioversion, and AF ablation, is an important component in the management of patients with atrial fibrillation (AF). Catheter ablation for AF, mainly targeting isolation of the pulmonary veins (AF ablation), has markedly improved the effectiveness of rhythm control therapy. Rhythm control improves symptoms and quality of life in patients with symptomatic AF. AF ablation maintains sinus rhythm more effectively than antiarrhythmic drug therapy. Antiarrhythmic drugs remain effective after AF ablation, underpinning the synergistic mechanisms of action of AF ablation and antiarrhythmic drugs. Different lifestyle interventions might additionally improve symptoms and rhythm stability in patients with AF. AF ablation appears to improve left ventricular function in a subset of patients. Summarized, rhythm control therapy in patients with symptomatic AF is safe and improves quality of life, including elderly patients with stroke risk factors. Further studies are needed to determine whether rhythm control therapy reduces AF-related complications while improving patient outcome with regard to prognosis.

KW - Anti-Arrhythmia Agents/therapeutic use

KW - Atrial Fibrillation/complications

KW - Catheter Ablation

KW - Electric Countershock

KW - Humans

KW - Quality of Life

KW - Stroke/etiology

KW - Ventricular Function, Left/physiology

U2 - 10.1055/a-0969-6352

DO - 10.1055/a-0969-6352

M3 - SCORING: Review

C2 - 32294780

VL - 145

SP - 543

EP - 549

JO - DEUT MED WOCHENSCHR

JF - DEUT MED WOCHENSCHR

SN - 0012-0472

IS - 8

ER -