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Value of (18) F-FDG PET/MRI for the outcome of CT-guided facet block therapy in cervical facet syndrome: initial results

Standard

Value of (18) F-FDG PET/MRI for the outcome of CT-guided facet block therapy in cervical facet syndrome: initial results. / Sawicki, Lino M; Schaarschmidt, Benedikt M; Heusch, Philipp; Buchbender, Christian; Rosenbaum-Krumme, Sandra; Umutlu, Lale; Eicker, Sven O; Bockisch, Andreas; Antoch, Gerald; Floeth, Frank W.

In: J MED IMAG RADIAT ON, Vol. 61, No. 3, 06.2017, p. 327-333.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Sawicki, LM, Schaarschmidt, BM, Heusch, P, Buchbender, C, Rosenbaum-Krumme, S, Umutlu, L, Eicker, SO, Bockisch, A, Antoch, G & Floeth, FW 2017, 'Value of (18) F-FDG PET/MRI for the outcome of CT-guided facet block therapy in cervical facet syndrome: initial results', J MED IMAG RADIAT ON, vol. 61, no. 3, pp. 327-333. https://doi.org/10.1111/1754-9485.12565

APA

Sawicki, L. M., Schaarschmidt, B. M., Heusch, P., Buchbender, C., Rosenbaum-Krumme, S., Umutlu, L., Eicker, S. O., Bockisch, A., Antoch, G., & Floeth, F. W. (2017). Value of (18) F-FDG PET/MRI for the outcome of CT-guided facet block therapy in cervical facet syndrome: initial results. J MED IMAG RADIAT ON, 61(3), 327-333. https://doi.org/10.1111/1754-9485.12565

Vancouver

Sawicki LM, Schaarschmidt BM, Heusch P, Buchbender C, Rosenbaum-Krumme S, Umutlu L et al. Value of (18) F-FDG PET/MRI for the outcome of CT-guided facet block therapy in cervical facet syndrome: initial results. J MED IMAG RADIAT ON. 2017 Jun;61(3):327-333. https://doi.org/10.1111/1754-9485.12565

Bibtex

@article{6edf4095fcca402eaf77ba91e97b50ed,
title = "Value of (18) F-FDG PET/MRI for the outcome of CT-guided facet block therapy in cervical facet syndrome: initial results",
abstract = "INTRODUCTION: The aim of this study was to evaluate the ability of (18) F-fluorodeoxyglucose positron emission tomography/magnetic resonance imaging ((18) F-FDG PET/MRI) to detect PET-positive cervical facet arthropathy and identify patients who benefit from facet block therapy.METHODS: Ten patients with cervical facet syndrome (mean age: 65 ± 12 years) underwent (18) F-FDG PET/MRI of the neck. Focal (18) F-FDG uptake in PET-positive facet joints served as target for computed tomography (CT)-guided facet blocks. In PET-negative patients, the target joint for facet block therapy was selected by current clinical standards considering the level of maximum facet arthrosis and pain. Neck pain was measured on visual analogue scale (VAS) before and after therapy. Bone marrow signal intensity (SI) ratio on turbo inversion recovery magnitude (TIRM) images and maximum standard uptake values (SUVmax) was calculated for each facet joint. Pearson's correlation coefficient (r) was calculated between bone marrow SI ratios on TIRM and SUVmax.RESULTS: (18) F-FDG PET/MRI detected PET-positive facet arthropathy in six patients. Patients with PET-positive facet arthropathy had significantly less pain compared with the pretreatment pain 3 h (P = 0.002), 4 weeks (P = 0.002) and 3 months (P = 0.026) after facet block therapy. Pain did not change significantly in patients with PET-negative facet arthropathy. TIRM SI ratio was higher in PET-positive facet arthropathy than in PET-negative facet arthropathy (P < 0.001). Correlation was strong between bone marrow SI ratio on TIRM images and SUVmax (r = 0.7; P < 0.001).CONCLUSIONS: (18) F-FDG PET/MRI can detect PET-positive cervical facet arthropathy and help to identify patients benefitting from facet block therapy. Bone marrow TIRM SI ratio might be a surrogate for PET-positive facet arthropathy.",
author = "Sawicki, {Lino M} and Schaarschmidt, {Benedikt M} and Philipp Heusch and Christian Buchbender and Sandra Rosenbaum-Krumme and Lale Umutlu and Eicker, {Sven O} and Andreas Bockisch and Gerald Antoch and Floeth, {Frank W}",
note = "{\textcopyright} 2016 The Royal Australian and New Zealand College of Radiologists.",
year = "2017",
month = jun,
doi = "10.1111/1754-9485.12565",
language = "English",
volume = "61",
pages = "327--333",
journal = "J MED IMAG RADIAT ON",
issn = "1754-9477",
publisher = "Wiley-Blackwell",
number = "3",

}

RIS

TY - JOUR

T1 - Value of (18) F-FDG PET/MRI for the outcome of CT-guided facet block therapy in cervical facet syndrome: initial results

AU - Sawicki, Lino M

AU - Schaarschmidt, Benedikt M

AU - Heusch, Philipp

AU - Buchbender, Christian

AU - Rosenbaum-Krumme, Sandra

AU - Umutlu, Lale

AU - Eicker, Sven O

AU - Bockisch, Andreas

AU - Antoch, Gerald

AU - Floeth, Frank W

N1 - © 2016 The Royal Australian and New Zealand College of Radiologists.

PY - 2017/6

Y1 - 2017/6

N2 - INTRODUCTION: The aim of this study was to evaluate the ability of (18) F-fluorodeoxyglucose positron emission tomography/magnetic resonance imaging ((18) F-FDG PET/MRI) to detect PET-positive cervical facet arthropathy and identify patients who benefit from facet block therapy.METHODS: Ten patients with cervical facet syndrome (mean age: 65 ± 12 years) underwent (18) F-FDG PET/MRI of the neck. Focal (18) F-FDG uptake in PET-positive facet joints served as target for computed tomography (CT)-guided facet blocks. In PET-negative patients, the target joint for facet block therapy was selected by current clinical standards considering the level of maximum facet arthrosis and pain. Neck pain was measured on visual analogue scale (VAS) before and after therapy. Bone marrow signal intensity (SI) ratio on turbo inversion recovery magnitude (TIRM) images and maximum standard uptake values (SUVmax) was calculated for each facet joint. Pearson's correlation coefficient (r) was calculated between bone marrow SI ratios on TIRM and SUVmax.RESULTS: (18) F-FDG PET/MRI detected PET-positive facet arthropathy in six patients. Patients with PET-positive facet arthropathy had significantly less pain compared with the pretreatment pain 3 h (P = 0.002), 4 weeks (P = 0.002) and 3 months (P = 0.026) after facet block therapy. Pain did not change significantly in patients with PET-negative facet arthropathy. TIRM SI ratio was higher in PET-positive facet arthropathy than in PET-negative facet arthropathy (P < 0.001). Correlation was strong between bone marrow SI ratio on TIRM images and SUVmax (r = 0.7; P < 0.001).CONCLUSIONS: (18) F-FDG PET/MRI can detect PET-positive cervical facet arthropathy and help to identify patients benefitting from facet block therapy. Bone marrow TIRM SI ratio might be a surrogate for PET-positive facet arthropathy.

AB - INTRODUCTION: The aim of this study was to evaluate the ability of (18) F-fluorodeoxyglucose positron emission tomography/magnetic resonance imaging ((18) F-FDG PET/MRI) to detect PET-positive cervical facet arthropathy and identify patients who benefit from facet block therapy.METHODS: Ten patients with cervical facet syndrome (mean age: 65 ± 12 years) underwent (18) F-FDG PET/MRI of the neck. Focal (18) F-FDG uptake in PET-positive facet joints served as target for computed tomography (CT)-guided facet blocks. In PET-negative patients, the target joint for facet block therapy was selected by current clinical standards considering the level of maximum facet arthrosis and pain. Neck pain was measured on visual analogue scale (VAS) before and after therapy. Bone marrow signal intensity (SI) ratio on turbo inversion recovery magnitude (TIRM) images and maximum standard uptake values (SUVmax) was calculated for each facet joint. Pearson's correlation coefficient (r) was calculated between bone marrow SI ratios on TIRM and SUVmax.RESULTS: (18) F-FDG PET/MRI detected PET-positive facet arthropathy in six patients. Patients with PET-positive facet arthropathy had significantly less pain compared with the pretreatment pain 3 h (P = 0.002), 4 weeks (P = 0.002) and 3 months (P = 0.026) after facet block therapy. Pain did not change significantly in patients with PET-negative facet arthropathy. TIRM SI ratio was higher in PET-positive facet arthropathy than in PET-negative facet arthropathy (P < 0.001). Correlation was strong between bone marrow SI ratio on TIRM images and SUVmax (r = 0.7; P < 0.001).CONCLUSIONS: (18) F-FDG PET/MRI can detect PET-positive cervical facet arthropathy and help to identify patients benefitting from facet block therapy. Bone marrow TIRM SI ratio might be a surrogate for PET-positive facet arthropathy.

U2 - 10.1111/1754-9485.12565

DO - 10.1111/1754-9485.12565

M3 - SCORING: Journal article

C2 - 27885810

VL - 61

SP - 327

EP - 333

JO - J MED IMAG RADIAT ON

JF - J MED IMAG RADIAT ON

SN - 1754-9477

IS - 3

ER -