Update Breast Cancer 2023 Part 2 - Advanced-Stage Breast Cancer
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Update Breast Cancer 2023 Part 2 - Advanced-Stage Breast Cancer. / Lux, Michael P; Hartkopf, Andreas D; Fehm, Tanja N; Welslau, Manfred; Müller, Volkmar; Schütz, Florian; Fasching, Peter A; Janni, Wolfgang; Witzel, Isabell; Thomssen, Christoph; Beierlein, Milena; Belleville, Erik; Untch, Michael; Thill, Marc; Tesch, Hans; Ditsch, Nina; Aktas, Bahriye; Banys-Paluchowski, Maggie; Kolberg-Liedtke, Cornelia; Wöckel, Achim; Kolberg, Hans-Christian; Harbeck, Nadia; Bartsch, Rupert; Schneeweiss, Andreas; Ettl, Johannes; Würstlein, Rachel; Krug, David; Taran, Florin-Andrei; Lüftner, Diana; Stickeler, Elmar.
In: GEBURTSH FRAUENHEILK, Vol. 83, No. 6, 06.2023, p. 664-672.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Update Breast Cancer 2023 Part 2 - Advanced-Stage Breast Cancer
AU - Lux, Michael P
AU - Hartkopf, Andreas D
AU - Fehm, Tanja N
AU - Welslau, Manfred
AU - Müller, Volkmar
AU - Schütz, Florian
AU - Fasching, Peter A
AU - Janni, Wolfgang
AU - Witzel, Isabell
AU - Thomssen, Christoph
AU - Beierlein, Milena
AU - Belleville, Erik
AU - Untch, Michael
AU - Thill, Marc
AU - Tesch, Hans
AU - Ditsch, Nina
AU - Aktas, Bahriye
AU - Banys-Paluchowski, Maggie
AU - Kolberg-Liedtke, Cornelia
AU - Wöckel, Achim
AU - Kolberg, Hans-Christian
AU - Harbeck, Nadia
AU - Bartsch, Rupert
AU - Schneeweiss, Andreas
AU - Ettl, Johannes
AU - Würstlein, Rachel
AU - Krug, David
AU - Taran, Florin-Andrei
AU - Lüftner, Diana
AU - Stickeler, Elmar
N1 - The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).
PY - 2023/6
Y1 - 2023/6
N2 - In recent years, a number of new therapies have led to advances in the treatment of patients with advanced breast carcinoma. These substances are mainly CDK4/6 inhibitors and other substances that can overcome endocrine resistance, oral selective estrogen receptor degraders, antibody drug conjugates (ADCs), and PARP inhibitors. This review summarizes and evaluates the latest study results that have been published in recent months. This includes the overall survival data of the Destiny-Breast03 study, the first analysis of the CAPItello-291 study, the comparison of CDK4/6 inhibitor treatment with chemotherapy in the first line of therapy (RIGHT Choice study), the first analysis of the Destiny-Breast02 study in the treatment setting after T-DM1 treatment, and the first analysis of the Serena-2 study. Most of these studies have the potential to significantly change the therapeutic landscape for patients with advanced breast carcinoma and show that the continued rapid development of new therapies is always producing new results.
AB - In recent years, a number of new therapies have led to advances in the treatment of patients with advanced breast carcinoma. These substances are mainly CDK4/6 inhibitors and other substances that can overcome endocrine resistance, oral selective estrogen receptor degraders, antibody drug conjugates (ADCs), and PARP inhibitors. This review summarizes and evaluates the latest study results that have been published in recent months. This includes the overall survival data of the Destiny-Breast03 study, the first analysis of the CAPItello-291 study, the comparison of CDK4/6 inhibitor treatment with chemotherapy in the first line of therapy (RIGHT Choice study), the first analysis of the Destiny-Breast02 study in the treatment setting after T-DM1 treatment, and the first analysis of the Serena-2 study. Most of these studies have the potential to significantly change the therapeutic landscape for patients with advanced breast carcinoma and show that the continued rapid development of new therapies is always producing new results.
U2 - 10.1055/a-2074-0125
DO - 10.1055/a-2074-0125
M3 - SCORING: Journal article
C2 - 37916184
VL - 83
SP - 664
EP - 672
JO - GEBURTSH FRAUENHEILK
JF - GEBURTSH FRAUENHEILK
SN - 0016-5751
IS - 6
ER -