Update Breast Cancer 2020 Part 2 - Advanced Breast Cancer

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Update Breast Cancer 2020 Part 2 - Advanced Breast Cancer : New Treatments and Implementation of Therapies with Companion Diagnostics. / Lüftner, Diana; Schneeweiss, Andreas; Hartkopf, Andreas D; Müller, Volkmar; Wöckel, Achim; Janni, Wolfgang; Ettl, Johannes; Belleville, Erik; Schütz, Florian; Thill, Marc; Huober, Jens; Fasching, Peter A; Kolberg, Hans-Christian; Pöschke, Patrik; Welslau, Manfred; Overkamp, Friedrich; Tesch, Hans; Fehm, Tanja N; Lux, Michael P.

In: GEBURTSH FRAUENHEILK, Vol. 80, No. 4, 04.2020, p. 391-398.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

Harvard

Lüftner, D, Schneeweiss, A, Hartkopf, AD, Müller, V, Wöckel, A, Janni, W, Ettl, J, Belleville, E, Schütz, F, Thill, M, Huober, J, Fasching, PA, Kolberg, H-C, Pöschke, P, Welslau, M, Overkamp, F, Tesch, H, Fehm, TN & Lux, MP 2020, 'Update Breast Cancer 2020 Part 2 - Advanced Breast Cancer: New Treatments and Implementation of Therapies with Companion Diagnostics', GEBURTSH FRAUENHEILK, vol. 80, no. 4, pp. 391-398. https://doi.org/10.1055/a-1111-8775

APA

Lüftner, D., Schneeweiss, A., Hartkopf, A. D., Müller, V., Wöckel, A., Janni, W., Ettl, J., Belleville, E., Schütz, F., Thill, M., Huober, J., Fasching, P. A., Kolberg, H-C., Pöschke, P., Welslau, M., Overkamp, F., Tesch, H., Fehm, T. N., & Lux, M. P. (2020). Update Breast Cancer 2020 Part 2 - Advanced Breast Cancer: New Treatments and Implementation of Therapies with Companion Diagnostics. GEBURTSH FRAUENHEILK, 80(4), 391-398. https://doi.org/10.1055/a-1111-8775

Vancouver

Bibtex

@article{c1df8c9bf090416dafe4344d0feeee9d,
title = "Update Breast Cancer 2020 Part 2 - Advanced Breast Cancer: New Treatments and Implementation of Therapies with Companion Diagnostics",
abstract = "For patients with locally advanced or metastatic breast cancer, new and effective therapies such as CDK4/6 inhibitors, PARP inhibitors and a PD-L1 inhibitor have been introduced in recent years. This review presents an update on the available studies with their data. In addition, two innovative anti-HER2 therapies are presented (trastuzumab-deruxtecan and tucatinib) for which the results from new studies have been reported. Molecular tests offer the possibility of defining patient populations or also monitoring courses of therapy. This can help identify patients with specific characteristics in order to provide them with individually targeted therapy within the framework of studies. In a large study, the benefit of such a biomarker study was able to be described for the first time.",
author = "Diana L{\"u}ftner and Andreas Schneeweiss and Hartkopf, {Andreas D} and Volkmar M{\"u}ller and Achim W{\"o}ckel and Wolfgang Janni and Johannes Ettl and Erik Belleville and Florian Sch{\"u}tz and Marc Thill and Jens Huober and Fasching, {Peter A} and Hans-Christian Kolberg and Patrik P{\"o}schke and Manfred Welslau and Friedrich Overkamp and Hans Tesch and Fehm, {Tanja N} and Lux, {Michael P}",
year = "2020",
month = apr,
doi = "10.1055/a-1111-8775",
language = "English",
volume = "80",
pages = "391--398",
journal = "GEBURTSH FRAUENHEILK",
issn = "0016-5751",
publisher = "Georg Thieme Verlag KG",
number = "4",

}

RIS

TY - JOUR

T1 - Update Breast Cancer 2020 Part 2 - Advanced Breast Cancer

T2 - New Treatments and Implementation of Therapies with Companion Diagnostics

AU - Lüftner, Diana

AU - Schneeweiss, Andreas

AU - Hartkopf, Andreas D

AU - Müller, Volkmar

AU - Wöckel, Achim

AU - Janni, Wolfgang

AU - Ettl, Johannes

AU - Belleville, Erik

AU - Schütz, Florian

AU - Thill, Marc

AU - Huober, Jens

AU - Fasching, Peter A

AU - Kolberg, Hans-Christian

AU - Pöschke, Patrik

AU - Welslau, Manfred

AU - Overkamp, Friedrich

AU - Tesch, Hans

AU - Fehm, Tanja N

AU - Lux, Michael P

PY - 2020/4

Y1 - 2020/4

N2 - For patients with locally advanced or metastatic breast cancer, new and effective therapies such as CDK4/6 inhibitors, PARP inhibitors and a PD-L1 inhibitor have been introduced in recent years. This review presents an update on the available studies with their data. In addition, two innovative anti-HER2 therapies are presented (trastuzumab-deruxtecan and tucatinib) for which the results from new studies have been reported. Molecular tests offer the possibility of defining patient populations or also monitoring courses of therapy. This can help identify patients with specific characteristics in order to provide them with individually targeted therapy within the framework of studies. In a large study, the benefit of such a biomarker study was able to be described for the first time.

AB - For patients with locally advanced or metastatic breast cancer, new and effective therapies such as CDK4/6 inhibitors, PARP inhibitors and a PD-L1 inhibitor have been introduced in recent years. This review presents an update on the available studies with their data. In addition, two innovative anti-HER2 therapies are presented (trastuzumab-deruxtecan and tucatinib) for which the results from new studies have been reported. Molecular tests offer the possibility of defining patient populations or also monitoring courses of therapy. This can help identify patients with specific characteristics in order to provide them with individually targeted therapy within the framework of studies. In a large study, the benefit of such a biomarker study was able to be described for the first time.

U2 - 10.1055/a-1111-8775

DO - 10.1055/a-1111-8775

M3 - SCORING: Journal article

C2 - 32322108

VL - 80

SP - 391

EP - 398

JO - GEBURTSH FRAUENHEILK

JF - GEBURTSH FRAUENHEILK

SN - 0016-5751

IS - 4

ER -