Update Breast Cancer 2017 - Implementation of Novel Therapies

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Update Breast Cancer 2017 - Implementation of Novel Therapies. / Lux, Michael P; Janni, Wolfgang; Hartkopf, Andreas D; Nabieva, Naiba; Taran, Florin-Andrei; Overkamp, Friedrich; Kolberg, Hans-Christian; Hadji, Peyman; Tesch, Hans; Ettl, Johannes; Huober, Jens B; Lüftner, Diana; Wallwiener, Markus; Müller, Volkmar; Beckmann, Matthias W; Belleville, Erik; Fehm, Tanja N; Wallwiener, Diethelm; Brucker, Sara Y; Schneeweiss, Andreas; Fasching, Peter A.

In: GEBURTSH FRAUENHEILK, Vol. 77, No. 12, 12.2017, p. 1281-1290.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

Harvard

Lux, MP, Janni, W, Hartkopf, AD, Nabieva, N, Taran, F-A, Overkamp, F, Kolberg, H-C, Hadji, P, Tesch, H, Ettl, J, Huober, JB, Lüftner, D, Wallwiener, M, Müller, V, Beckmann, MW, Belleville, E, Fehm, TN, Wallwiener, D, Brucker, SY, Schneeweiss, A & Fasching, PA 2017, 'Update Breast Cancer 2017 - Implementation of Novel Therapies', GEBURTSH FRAUENHEILK, vol. 77, no. 12, pp. 1281-1290. https://doi.org/10.1055/s-0043-122885

APA

Lux, M. P., Janni, W., Hartkopf, A. D., Nabieva, N., Taran, F-A., Overkamp, F., Kolberg, H-C., Hadji, P., Tesch, H., Ettl, J., Huober, J. B., Lüftner, D., Wallwiener, M., Müller, V., Beckmann, M. W., Belleville, E., Fehm, T. N., Wallwiener, D., Brucker, S. Y., ... Fasching, P. A. (2017). Update Breast Cancer 2017 - Implementation of Novel Therapies. GEBURTSH FRAUENHEILK, 77(12), 1281-1290. https://doi.org/10.1055/s-0043-122885

Vancouver

Lux MP, Janni W, Hartkopf AD, Nabieva N, Taran F-A, Overkamp F et al. Update Breast Cancer 2017 - Implementation of Novel Therapies. GEBURTSH FRAUENHEILK. 2017 Dec;77(12):1281-1290. https://doi.org/10.1055/s-0043-122885

Bibtex

@article{428b3021ca9543a58a64bdb7ac5461de,
title = "Update Breast Cancer 2017 - Implementation of Novel Therapies",
abstract = "In recent years, numerous new therapy options for patients with breast cancer have been developed in clinical studies, with some options already approved for routine treatment. As the speed at which innovations are introduced increases, the importance of conferences also increases, as conferences are where the data underpinning new therapies are usually presented for the first time. This review looks at publications of the ASCO (American Society of Clinical Oncology) and ESMO (European Society of Medical Oncology) conferences in 2017, summarizes them and evaluates them in the context of existing data. The focus is on new insights for neoadjuvant therapy and new treatment options in the metastatic setting, such as the use of CDK4/6 inhibitors or PARP inhibitors. The first results of treatments with checkpoint inhibitors are presented. With the patent expiry of trastuzumab, a number of study results for trastuzumab biosimilars have also been published. The digitization of patient care provides the first results on quality of life and prognosis of patients with advanced cancer. Digital communications between patients and physicians are being evaluated in several studies in Germany. As the discussion about patient-relevant endpoints for patients in the metastatic setting continues, overall survival rates from studies of big endocrine-based therapies are urgently needed. Preliminary analyses of small study cohorts offer initial insights. In the context of improving patient care, in the coming years, questions will center on which patients particularly benefit from certain therapies and which patients need particular protection from specific side effects. Questions about these predictors are raised in many scientific projects as attention increasingly focuses on this topic.",
keywords = "Journal Article",
author = "Lux, {Michael P} and Wolfgang Janni and Hartkopf, {Andreas D} and Naiba Nabieva and Florin-Andrei Taran and Friedrich Overkamp and Hans-Christian Kolberg and Peyman Hadji and Hans Tesch and Johannes Ettl and Huober, {Jens B} and Diana L{\"u}ftner and Markus Wallwiener and Volkmar M{\"u}ller and Beckmann, {Matthias W} and Erik Belleville and Fehm, {Tanja N} and Diethelm Wallwiener and Brucker, {Sara Y} and Andreas Schneeweiss and Fasching, {Peter A}",
year = "2017",
month = dec,
doi = "10.1055/s-0043-122885",
language = "English",
volume = "77",
pages = "1281--1290",
journal = "GEBURTSH FRAUENHEILK",
issn = "0016-5751",
publisher = "Georg Thieme Verlag KG",
number = "12",

}

RIS

TY - JOUR

T1 - Update Breast Cancer 2017 - Implementation of Novel Therapies

AU - Lux, Michael P

AU - Janni, Wolfgang

AU - Hartkopf, Andreas D

AU - Nabieva, Naiba

AU - Taran, Florin-Andrei

AU - Overkamp, Friedrich

AU - Kolberg, Hans-Christian

AU - Hadji, Peyman

AU - Tesch, Hans

AU - Ettl, Johannes

AU - Huober, Jens B

AU - Lüftner, Diana

AU - Wallwiener, Markus

AU - Müller, Volkmar

AU - Beckmann, Matthias W

AU - Belleville, Erik

AU - Fehm, Tanja N

AU - Wallwiener, Diethelm

AU - Brucker, Sara Y

AU - Schneeweiss, Andreas

AU - Fasching, Peter A

PY - 2017/12

Y1 - 2017/12

N2 - In recent years, numerous new therapy options for patients with breast cancer have been developed in clinical studies, with some options already approved for routine treatment. As the speed at which innovations are introduced increases, the importance of conferences also increases, as conferences are where the data underpinning new therapies are usually presented for the first time. This review looks at publications of the ASCO (American Society of Clinical Oncology) and ESMO (European Society of Medical Oncology) conferences in 2017, summarizes them and evaluates them in the context of existing data. The focus is on new insights for neoadjuvant therapy and new treatment options in the metastatic setting, such as the use of CDK4/6 inhibitors or PARP inhibitors. The first results of treatments with checkpoint inhibitors are presented. With the patent expiry of trastuzumab, a number of study results for trastuzumab biosimilars have also been published. The digitization of patient care provides the first results on quality of life and prognosis of patients with advanced cancer. Digital communications between patients and physicians are being evaluated in several studies in Germany. As the discussion about patient-relevant endpoints for patients in the metastatic setting continues, overall survival rates from studies of big endocrine-based therapies are urgently needed. Preliminary analyses of small study cohorts offer initial insights. In the context of improving patient care, in the coming years, questions will center on which patients particularly benefit from certain therapies and which patients need particular protection from specific side effects. Questions about these predictors are raised in many scientific projects as attention increasingly focuses on this topic.

AB - In recent years, numerous new therapy options for patients with breast cancer have been developed in clinical studies, with some options already approved for routine treatment. As the speed at which innovations are introduced increases, the importance of conferences also increases, as conferences are where the data underpinning new therapies are usually presented for the first time. This review looks at publications of the ASCO (American Society of Clinical Oncology) and ESMO (European Society of Medical Oncology) conferences in 2017, summarizes them and evaluates them in the context of existing data. The focus is on new insights for neoadjuvant therapy and new treatment options in the metastatic setting, such as the use of CDK4/6 inhibitors or PARP inhibitors. The first results of treatments with checkpoint inhibitors are presented. With the patent expiry of trastuzumab, a number of study results for trastuzumab biosimilars have also been published. The digitization of patient care provides the first results on quality of life and prognosis of patients with advanced cancer. Digital communications between patients and physicians are being evaluated in several studies in Germany. As the discussion about patient-relevant endpoints for patients in the metastatic setting continues, overall survival rates from studies of big endocrine-based therapies are urgently needed. Preliminary analyses of small study cohorts offer initial insights. In the context of improving patient care, in the coming years, questions will center on which patients particularly benefit from certain therapies and which patients need particular protection from specific side effects. Questions about these predictors are raised in many scientific projects as attention increasingly focuses on this topic.

KW - Journal Article

U2 - 10.1055/s-0043-122885

DO - 10.1055/s-0043-122885

M3 - SCORING: Journal article

C2 - 29269955

VL - 77

SP - 1281

EP - 1290

JO - GEBURTSH FRAUENHEILK

JF - GEBURTSH FRAUENHEILK

SN - 0016-5751

IS - 12

ER -