Understanding spermatogenesis is a prerequisite for treatment.
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Understanding spermatogenesis is a prerequisite for treatment. / Holstein, Adolf-Friedrich; Schulze, Wolfgang; Davidoff, Michail.
In: REPROD BIOL ENDOCRIN, Vol. 1, 2003, p. 107.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Understanding spermatogenesis is a prerequisite for treatment.
AU - Holstein, Adolf-Friedrich
AU - Schulze, Wolfgang
AU - Davidoff, Michail
PY - 2003
Y1 - 2003
N2 - Throughout spermatogenesis multiplication, maturation and differentiation of germ cells results in the formation of the male gamete. The understanding of spermatogenesis needs detailed informations about the organization of the germinal epithelium, the structure and function of different types of germ cells, endocrine and paracrine cells and mechanisms, intratesticular and extratesticular regulation of spermatogenesis. Normal germ cells must be discriminated from malformed, apoptotic and degenerating germ cells and tumor cells. Identification of the border line between normal and disturbed spermatogenesis substantiate the diagnosis of impaired male fertility. The profound knowledge of the complicate process of spermatogenesis and all cells or cell systems involved with is the prerequisite to develop concepts for therapy of male infertility or to handle germ cells in the management of assisted reproduction.
AB - Throughout spermatogenesis multiplication, maturation and differentiation of germ cells results in the formation of the male gamete. The understanding of spermatogenesis needs detailed informations about the organization of the germinal epithelium, the structure and function of different types of germ cells, endocrine and paracrine cells and mechanisms, intratesticular and extratesticular regulation of spermatogenesis. Normal germ cells must be discriminated from malformed, apoptotic and degenerating germ cells and tumor cells. Identification of the border line between normal and disturbed spermatogenesis substantiate the diagnosis of impaired male fertility. The profound knowledge of the complicate process of spermatogenesis and all cells or cell systems involved with is the prerequisite to develop concepts for therapy of male infertility or to handle germ cells in the management of assisted reproduction.
U2 - 10.1186/1477-7827-1-107
DO - 10.1186/1477-7827-1-107
M3 - SCORING: Zeitschriftenaufsatz
VL - 1
SP - 107
ER -
