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Understanding Mortality of Femoral Fractures Following Low-Impact Trauma in Persons With and Without Care Need

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Understanding Mortality of Femoral Fractures Following Low-Impact Trauma in Persons With and Without Care Need. / Bluhmki, Tobias; Peter, Raphael Simon; Rapp, Kilian; König, Hans-Helmut; Becker, Clemens; Lindlbauer, Ivonne; Rothenbacher, Dietrich; Beyersmann, Jan; Büchele, Gisela.

In: J AM MED DIR ASSOC, Vol. 18, No. 3, 01.03.2017, p. 221-226.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Bluhmki, T, Peter, RS, Rapp, K, König, H-H, Becker, C, Lindlbauer, I, Rothenbacher, D, Beyersmann, J & Büchele, G 2017, 'Understanding Mortality of Femoral Fractures Following Low-Impact Trauma in Persons With and Without Care Need', J AM MED DIR ASSOC, vol. 18, no. 3, pp. 221-226. https://doi.org/10.1016/j.jamda.2016.08.022

APA

Bluhmki, T., Peter, R. S., Rapp, K., König, H-H., Becker, C., Lindlbauer, I., Rothenbacher, D., Beyersmann, J., & Büchele, G. (2017). Understanding Mortality of Femoral Fractures Following Low-Impact Trauma in Persons With and Without Care Need. J AM MED DIR ASSOC, 18(3), 221-226. https://doi.org/10.1016/j.jamda.2016.08.022

Vancouver

Bluhmki T, Peter RS, Rapp K, König H-H, Becker C, Lindlbauer I et al. Understanding Mortality of Femoral Fractures Following Low-Impact Trauma in Persons With and Without Care Need. J AM MED DIR ASSOC. 2017 Mar 1;18(3):221-226. https://doi.org/10.1016/j.jamda.2016.08.022

Bibtex

@article{b1276ff6395e4edeba56c3e0aa6f28e4,
title = "Understanding Mortality of Femoral Fractures Following Low-Impact Trauma in Persons With and Without Care Need",
abstract = "OBJECTIVES: Persons with osteoporotic fracture history are subject to an increased risk for subsequent fractures and mortality. The aim of this retrospective study was to investigate the impact of a previous osteoporotic low-impact (fragility) index fracture (eg, forearm, lower leg) on mortality of a subsequent femoral fracture.DESIGN: Retrospective cohort study.PARTICIPANTS/MEASUREMENTS: Claims data of a German health insurance agency including >1.2 million insurants aged 65 years or older and observed between 2004 and 2009.METHODS: A multistate model was developed handling index fractures and care need as time-dependent exposures, while age was chosen as the underlying time scale. Excess risks were expressed as differences in cause-specific hazards. Nelson-Aalen estimates were used for their nonparametric estimation. Time-simultaneous statistical inference was based on confidence bands provided by wild bootstrap resampling.RESULTS: Excess femoral fracture risk increased with progressive age and was highest in persons with care need. It was observed starting from an age of 79 years in women and 85 years in men onward. A prior index fracture increased mortality after a femoral fracture by increasing femoral fracture risk, while leaving the hazard of death after a subsequent femoral fracture unchanged.CONCLUSIONS: The results indicated that increased mortality of a subsequent femoral fracture is not triggered by an intrinsically increased mortality hazard but an increased femoral fracture incidence.",
author = "Tobias Bluhmki and Peter, {Raphael Simon} and Kilian Rapp and Hans-Helmut K{\"o}nig and Clemens Becker and Ivonne Lindlbauer and Dietrich Rothenbacher and Jan Beyersmann and Gisela B{\"u}chele",
note = "Copyright {\textcopyright} 2016 AMDA – The Society for Post-Acute and Long-Term Care Medicine. Published by Elsevier Inc. All rights reserved.",
year = "2017",
month = mar,
day = "1",
doi = "10.1016/j.jamda.2016.08.022",
language = "English",
volume = "18",
pages = "221--226",
journal = "J AM MED DIR ASSOC",
issn = "1525-8610",
publisher = "Elsevier Inc.",
number = "3",

}

RIS

TY - JOUR

T1 - Understanding Mortality of Femoral Fractures Following Low-Impact Trauma in Persons With and Without Care Need

AU - Bluhmki, Tobias

AU - Peter, Raphael Simon

AU - Rapp, Kilian

AU - König, Hans-Helmut

AU - Becker, Clemens

AU - Lindlbauer, Ivonne

AU - Rothenbacher, Dietrich

AU - Beyersmann, Jan

AU - Büchele, Gisela

N1 - Copyright © 2016 AMDA – The Society for Post-Acute and Long-Term Care Medicine. Published by Elsevier Inc. All rights reserved.

PY - 2017/3/1

Y1 - 2017/3/1

N2 - OBJECTIVES: Persons with osteoporotic fracture history are subject to an increased risk for subsequent fractures and mortality. The aim of this retrospective study was to investigate the impact of a previous osteoporotic low-impact (fragility) index fracture (eg, forearm, lower leg) on mortality of a subsequent femoral fracture.DESIGN: Retrospective cohort study.PARTICIPANTS/MEASUREMENTS: Claims data of a German health insurance agency including >1.2 million insurants aged 65 years or older and observed between 2004 and 2009.METHODS: A multistate model was developed handling index fractures and care need as time-dependent exposures, while age was chosen as the underlying time scale. Excess risks were expressed as differences in cause-specific hazards. Nelson-Aalen estimates were used for their nonparametric estimation. Time-simultaneous statistical inference was based on confidence bands provided by wild bootstrap resampling.RESULTS: Excess femoral fracture risk increased with progressive age and was highest in persons with care need. It was observed starting from an age of 79 years in women and 85 years in men onward. A prior index fracture increased mortality after a femoral fracture by increasing femoral fracture risk, while leaving the hazard of death after a subsequent femoral fracture unchanged.CONCLUSIONS: The results indicated that increased mortality of a subsequent femoral fracture is not triggered by an intrinsically increased mortality hazard but an increased femoral fracture incidence.

AB - OBJECTIVES: Persons with osteoporotic fracture history are subject to an increased risk for subsequent fractures and mortality. The aim of this retrospective study was to investigate the impact of a previous osteoporotic low-impact (fragility) index fracture (eg, forearm, lower leg) on mortality of a subsequent femoral fracture.DESIGN: Retrospective cohort study.PARTICIPANTS/MEASUREMENTS: Claims data of a German health insurance agency including >1.2 million insurants aged 65 years or older and observed between 2004 and 2009.METHODS: A multistate model was developed handling index fractures and care need as time-dependent exposures, while age was chosen as the underlying time scale. Excess risks were expressed as differences in cause-specific hazards. Nelson-Aalen estimates were used for their nonparametric estimation. Time-simultaneous statistical inference was based on confidence bands provided by wild bootstrap resampling.RESULTS: Excess femoral fracture risk increased with progressive age and was highest in persons with care need. It was observed starting from an age of 79 years in women and 85 years in men onward. A prior index fracture increased mortality after a femoral fracture by increasing femoral fracture risk, while leaving the hazard of death after a subsequent femoral fracture unchanged.CONCLUSIONS: The results indicated that increased mortality of a subsequent femoral fracture is not triggered by an intrinsically increased mortality hazard but an increased femoral fracture incidence.

U2 - 10.1016/j.jamda.2016.08.022

DO - 10.1016/j.jamda.2016.08.022

M3 - SCORING: Journal article

C2 - 27776984

VL - 18

SP - 221

EP - 226

JO - J AM MED DIR ASSOC

JF - J AM MED DIR ASSOC

SN - 1525-8610

IS - 3

ER -