Two Cases of Lassa Fever Successfully Treated with Ribavirin and Adjunct Dexamethasone for Concomitant Infections
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Two Cases of Lassa Fever Successfully Treated with Ribavirin and Adjunct Dexamethasone for Concomitant Infections. / Okogbenin, Sylvanus; Erameh, Cyril; Okoeguale, Joseph; Edeawe, Osahogie; Ekuaze, Esele; Iraoyah, Kelly; Agho, John; Groger, Mirjam; Kreuels, Benno; Oestereich, Lisa; Babatunde, Femi O; Akhideno, Peter; Günther, Stephan; Ramharter, Michael; Omansen, Till.
In: EMERG INFECT DIS, Vol. 28, No. 10, 10.2022, p. 2060-2063.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Two Cases of Lassa Fever Successfully Treated with Ribavirin and Adjunct Dexamethasone for Concomitant Infections
AU - Okogbenin, Sylvanus
AU - Erameh, Cyril
AU - Okoeguale, Joseph
AU - Edeawe, Osahogie
AU - Ekuaze, Esele
AU - Iraoyah, Kelly
AU - Agho, John
AU - Groger, Mirjam
AU - Kreuels, Benno
AU - Oestereich, Lisa
AU - Babatunde, Femi O
AU - Akhideno, Peter
AU - Günther, Stephan
AU - Ramharter, Michael
AU - Omansen, Till
PY - 2022/10
Y1 - 2022/10
N2 - Lassa fever is a viral hemorrhagic fever treated with supportive care and the broad-spectrum antiviral drug ribavirin. The pathophysiology, especially the role of hyperinflammation, of this disease is unknown. We report successful remission of complicated Lassa fever in 2 patients in Nigeria who received the antiinflammatory agent dexamethasone and standard ribavirin.
AB - Lassa fever is a viral hemorrhagic fever treated with supportive care and the broad-spectrum antiviral drug ribavirin. The pathophysiology, especially the role of hyperinflammation, of this disease is unknown. We report successful remission of complicated Lassa fever in 2 patients in Nigeria who received the antiinflammatory agent dexamethasone and standard ribavirin.
KW - Antiviral Agents/therapeutic use
KW - Dexamethasone/therapeutic use
KW - Humans
KW - Lassa Fever/diagnosis
KW - Lassa virus/genetics
KW - Ribavirin/therapeutic use
U2 - 10.3201/eid2810.220625
DO - 10.3201/eid2810.220625
M3 - SCORING: Journal article
C2 - 36148915
VL - 28
SP - 2060
EP - 2063
JO - EMERG INFECT DIS
JF - EMERG INFECT DIS
SN - 1080-6040
IS - 10
ER -