Tumour volume and high grade tumour volume are the best predictors of pathologic stage and biochemical recurrence after radical prostatectomy.

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Tumour volume and high grade tumour volume are the best predictors of pathologic stage and biochemical recurrence after radical prostatectomy. / Chun, Felix; Briganti, Alberto; Jeldres, Claudio; Gallina, Andrea; Erbersdobler, Andreas; Schlomm, Thorsten; Walz, Jochen; Eichelberg, Christian; Salomon, Georg; Haese, Alexander; Eichelberg, Eike; Ahyai, Sascha; Bénard, François; Huland, Hartwig; Graefen, Markus; Karakiewicz, Pierre I.

In: EUR J CANCER, Vol. 43, No. 3, 3, 2007, p. 536-543.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

Harvard

Chun, F, Briganti, A, Jeldres, C, Gallina, A, Erbersdobler, A, Schlomm, T, Walz, J, Eichelberg, C, Salomon, G, Haese, A, Eichelberg, E, Ahyai, S, Bénard, F, Huland, H, Graefen, M & Karakiewicz, PI 2007, 'Tumour volume and high grade tumour volume are the best predictors of pathologic stage and biochemical recurrence after radical prostatectomy.', EUR J CANCER, vol. 43, no. 3, 3, pp. 536-543. <http://www.ncbi.nlm.nih.gov/pubmed/17222546?dopt=Citation>

APA

Chun, F., Briganti, A., Jeldres, C., Gallina, A., Erbersdobler, A., Schlomm, T., Walz, J., Eichelberg, C., Salomon, G., Haese, A., Eichelberg, E., Ahyai, S., Bénard, F., Huland, H., Graefen, M., & Karakiewicz, P. I. (2007). Tumour volume and high grade tumour volume are the best predictors of pathologic stage and biochemical recurrence after radical prostatectomy. EUR J CANCER, 43(3), 536-543. [3]. http://www.ncbi.nlm.nih.gov/pubmed/17222546?dopt=Citation

Vancouver

Bibtex

@article{872acb6c4a68458082e5b632a6a29318,
title = "Tumour volume and high grade tumour volume are the best predictors of pathologic stage and biochemical recurrence after radical prostatectomy.",
abstract = "INTRODUCTION: Our goal was to examine to what extent tumour volume (TV) and percentage of high grade tumour volume (%HGTV) affect the rate of positive surgical margins and the rate of biochemical recurrence after radical prostatectomy. MATERIALS AND METHODS: TV and %HGTV were routinely planimetrically quantified in a cohort of 780 consecutive patients. Mean follow-up was 46.7 months. Multivariable regression models addressed two separate endpoints: positive surgical margins and biochemical recurrence. The increase in model predictive accuracy related to the addition of TV and %HGTV to radical prostatectomy stage and grade was assessed, after 200 bootstrap resamples to reduce overfit bias. RESULTS: In multivariable logistic regression models addressing positive surgical margins rate, predictive accuracy increased by 1.9% (p",
author = "Felix Chun and Alberto Briganti and Claudio Jeldres and Andrea Gallina and Andreas Erbersdobler and Thorsten Schlomm and Jochen Walz and Christian Eichelberg and Georg Salomon and Alexander Haese and Eike Eichelberg and Sascha Ahyai and Fran{\c c}ois B{\'e}nard and Hartwig Huland and Markus Graefen and Karakiewicz, {Pierre I}",
year = "2007",
language = "Deutsch",
volume = "43",
pages = "536--543",
journal = "EUR J CANCER",
issn = "0959-8049",
publisher = "Elsevier Limited",
number = "3",

}

RIS

TY - JOUR

T1 - Tumour volume and high grade tumour volume are the best predictors of pathologic stage and biochemical recurrence after radical prostatectomy.

AU - Chun, Felix

AU - Briganti, Alberto

AU - Jeldres, Claudio

AU - Gallina, Andrea

AU - Erbersdobler, Andreas

AU - Schlomm, Thorsten

AU - Walz, Jochen

AU - Eichelberg, Christian

AU - Salomon, Georg

AU - Haese, Alexander

AU - Eichelberg, Eike

AU - Ahyai, Sascha

AU - Bénard, François

AU - Huland, Hartwig

AU - Graefen, Markus

AU - Karakiewicz, Pierre I

PY - 2007

Y1 - 2007

N2 - INTRODUCTION: Our goal was to examine to what extent tumour volume (TV) and percentage of high grade tumour volume (%HGTV) affect the rate of positive surgical margins and the rate of biochemical recurrence after radical prostatectomy. MATERIALS AND METHODS: TV and %HGTV were routinely planimetrically quantified in a cohort of 780 consecutive patients. Mean follow-up was 46.7 months. Multivariable regression models addressed two separate endpoints: positive surgical margins and biochemical recurrence. The increase in model predictive accuracy related to the addition of TV and %HGTV to radical prostatectomy stage and grade was assessed, after 200 bootstrap resamples to reduce overfit bias. RESULTS: In multivariable logistic regression models addressing positive surgical margins rate, predictive accuracy increased by 1.9% (p

AB - INTRODUCTION: Our goal was to examine to what extent tumour volume (TV) and percentage of high grade tumour volume (%HGTV) affect the rate of positive surgical margins and the rate of biochemical recurrence after radical prostatectomy. MATERIALS AND METHODS: TV and %HGTV were routinely planimetrically quantified in a cohort of 780 consecutive patients. Mean follow-up was 46.7 months. Multivariable regression models addressed two separate endpoints: positive surgical margins and biochemical recurrence. The increase in model predictive accuracy related to the addition of TV and %HGTV to radical prostatectomy stage and grade was assessed, after 200 bootstrap resamples to reduce overfit bias. RESULTS: In multivariable logistic regression models addressing positive surgical margins rate, predictive accuracy increased by 1.9% (p

M3 - SCORING: Zeitschriftenaufsatz

VL - 43

SP - 536

EP - 543

JO - EUR J CANCER

JF - EUR J CANCER

SN - 0959-8049

IS - 3

M1 - 3

ER -