Research ExplorerPublications[Tumors of the urinary system. Current and old problems]

[Tumors of the urinary system. Current and old problems]

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[Tumors of the urinary system. Current and old problems]. / Minner, Sarah Jane Pauline; Sauter, Guido.

In: PATHOLOGE, Vol. 30, No. 2, 2, 2009, p. 179-184.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Minner, SJP & Sauter, G 2009, '[Tumors of the urinary system. Current and old problems]', PATHOLOGE, vol. 30, no. 2, 2, pp. 179-184. <http://www.ncbi.nlm.nih.gov/pubmed/19960299?dopt=Citation>

APA

Minner, S. J. P., & Sauter, G. (2009). [Tumors of the urinary system. Current and old problems]. PATHOLOGE, 30(2), 179-184. [2]. http://www.ncbi.nlm.nih.gov/pubmed/19960299?dopt=Citation

Vancouver

Minner SJP, Sauter G. [Tumors of the urinary system. Current and old problems]. PATHOLOGE. 2009;30(2):179-184. 2.

Bibtex

@article{42c1a2c9f44e42d7a821670a7ad7c61f,
title = "[Tumors of the urinary system. Current and old problems]",
abstract = "Principally there are two different types of bladder cancer. Non-invasive papillary low grade tumors (pTa G1-G2) are genetically stable, recur frequently but show a low risk of progression. On the other hand there are high grade tumors (pT1-4, carcinoma in situ), which are genetically unstable, show biologically aggressive behaviour and progress. The distinction between non-invasive (pTa) and minimal-invasive (pT1) is one of the most challenging areas in bladder pathology. Due to the lack of appropriate auxiliary analysis the diagnosis is based entirely on histopathology. P53 immunohistochemistry can be helpful in the assessment of recurring high grade neoplasia. Targeted therapy in bladder cancer is particularly interesting, since a high number of oncogenes are activated and overexpressed (e.g. HER2 and EGFR).",
author = "Minner, {Sarah Jane Pauline} and Guido Sauter",
year = "2009",
language = "Deutsch",
volume = "30",
pages = "179--184",
journal = "PATHOLOGE",
issn = "0172-8113",
publisher = "Springer",
number = "2",

}

RIS

TY - JOUR

T1 - [Tumors of the urinary system. Current and old problems]

AU - Minner, Sarah Jane Pauline

AU - Sauter, Guido

PY - 2009

Y1 - 2009

N2 - Principally there are two different types of bladder cancer. Non-invasive papillary low grade tumors (pTa G1-G2) are genetically stable, recur frequently but show a low risk of progression. On the other hand there are high grade tumors (pT1-4, carcinoma in situ), which are genetically unstable, show biologically aggressive behaviour and progress. The distinction between non-invasive (pTa) and minimal-invasive (pT1) is one of the most challenging areas in bladder pathology. Due to the lack of appropriate auxiliary analysis the diagnosis is based entirely on histopathology. P53 immunohistochemistry can be helpful in the assessment of recurring high grade neoplasia. Targeted therapy in bladder cancer is particularly interesting, since a high number of oncogenes are activated and overexpressed (e.g. HER2 and EGFR).

AB - Principally there are two different types of bladder cancer. Non-invasive papillary low grade tumors (pTa G1-G2) are genetically stable, recur frequently but show a low risk of progression. On the other hand there are high grade tumors (pT1-4, carcinoma in situ), which are genetically unstable, show biologically aggressive behaviour and progress. The distinction between non-invasive (pTa) and minimal-invasive (pT1) is one of the most challenging areas in bladder pathology. Due to the lack of appropriate auxiliary analysis the diagnosis is based entirely on histopathology. P53 immunohistochemistry can be helpful in the assessment of recurring high grade neoplasia. Targeted therapy in bladder cancer is particularly interesting, since a high number of oncogenes are activated and overexpressed (e.g. HER2 and EGFR).

M3 - SCORING: Zeitschriftenaufsatz

VL - 30

SP - 179

EP - 184

JO - PATHOLOGE

JF - PATHOLOGE

SN - 0172-8113

IS - 2

M1 - 2

ER -