Tumorreduktion plexiformer Neurofibrome im kraniofazialen und Halsbereich
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Tumorreduktion plexiformer Neurofibrome im kraniofazialen und Halsbereich. / Friedrich, R E; Gehrke, G; Giese, M; Mautner, V F; Schmelzle, R.
In: Mund Kiefer Gesichtschir, Vol. 2 Suppl 1, 01.05.1998, p. S86-90.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Tumorreduktion plexiformer Neurofibrome im kraniofazialen und Halsbereich
AU - Friedrich, R E
AU - Gehrke, G
AU - Giese, M
AU - Mautner, V F
AU - Schmelzle, R
PY - 1998/5/1
Y1 - 1998/5/1
N2 - Neurofibromatosis type 1 (NF1) is an autosomal dominant hereditary disease of high penetrance and variable expression. Epidemiologic data on craniofacial manifestations are still lacking. Up until now 74 patients with NF1 have been treated at the Department of Oral and Maxillofacial Surgery of the University of Hamburg. Forty-two patients presented periorbital and orbital neurofibromas varying in extension and in the severity of findings of the affected site. Surgical therapy is mainly based on tumour reduction, frequently combined with face-lifting. In our experience neurofibromas of the neck tend to be pseudo-encapsulated, facilitating the preparation of the tumour. On the other hand, identification and preparation of diffuse infiltrating neurofibromas in the trigeminal nerve region are difficult and local recurrence must be expected.
AB - Neurofibromatosis type 1 (NF1) is an autosomal dominant hereditary disease of high penetrance and variable expression. Epidemiologic data on craniofacial manifestations are still lacking. Up until now 74 patients with NF1 have been treated at the Department of Oral and Maxillofacial Surgery of the University of Hamburg. Forty-two patients presented periorbital and orbital neurofibromas varying in extension and in the severity of findings of the affected site. Surgical therapy is mainly based on tumour reduction, frequently combined with face-lifting. In our experience neurofibromas of the neck tend to be pseudo-encapsulated, facilitating the preparation of the tumour. On the other hand, identification and preparation of diffuse infiltrating neurofibromas in the trigeminal nerve region are difficult and local recurrence must be expected.
KW - Adult
KW - Child, Preschool
KW - Craniotomy
KW - Female
KW - Follow-Up Studies
KW - Head and Neck Neoplasms
KW - Humans
KW - Male
KW - Neurofibroma, Plexiform
KW - Neurofibromatosis 1
KW - Orbital Neoplasms
KW - Reoperation
KW - Rhytidoplasty
KW - Treatment Outcome
M3 - SCORING: Zeitschriftenaufsatz
C2 - 9658829
VL - 2 Suppl 1
SP - S86-90
ER -