Treatment of advanced heart failure in adults with congenital heart disease: a narrative review and clinical cases
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Treatment of advanced heart failure in adults with congenital heart disease: a narrative review and clinical cases. / Sinning, Christoph; Huntgeburth, Michael; Fukushima, Norihide; Tompkins, Rose; Huh, June; Tataneo, Shigeru; Diller, Gerhard-Paul; Chen, Yih-Sharng; Zengin, Elvin; Magnussen, Christina; Kaemmerer, Ann-Sophie; Cho, Yang Hyun; Blankenberg, Stefan; Rickers, Carsten; Harig, Frank; Weyand, Michael; Hübler, Michael; von Kodolitsch, Yskert; Oto, Öztekin; Zuckermann, Andreas; Kirchhof, Paulus; Baumgartner, Helmut; Reichenspurner, Hermann; Kobashigawa, Jon; Kaemmerer, Harald; Niwa, Koichiro.
In: CARDIOVASC DIAGN THE, Vol. 12, No. 5, 10.2022, p. 727-743.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
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TY - JOUR
T1 - Treatment of advanced heart failure in adults with congenital heart disease: a narrative review and clinical cases
AU - Sinning, Christoph
AU - Huntgeburth, Michael
AU - Fukushima, Norihide
AU - Tompkins, Rose
AU - Huh, June
AU - Tataneo, Shigeru
AU - Diller, Gerhard-Paul
AU - Chen, Yih-Sharng
AU - Zengin, Elvin
AU - Magnussen, Christina
AU - Kaemmerer, Ann-Sophie
AU - Cho, Yang Hyun
AU - Blankenberg, Stefan
AU - Rickers, Carsten
AU - Harig, Frank
AU - Weyand, Michael
AU - Hübler, Michael
AU - von Kodolitsch, Yskert
AU - Oto, Öztekin
AU - Zuckermann, Andreas
AU - Kirchhof, Paulus
AU - Baumgartner, Helmut
AU - Reichenspurner, Hermann
AU - Kobashigawa, Jon
AU - Kaemmerer, Harald
AU - Niwa, Koichiro
N1 - 2022 Cardiovascular Diagnosis and Therapy. All rights reserved.
PY - 2022/10
Y1 - 2022/10
N2 - BACKGROUND AND OBJECTIVE: The number of adults with congenital heart disease (ACHD) is increasing worldwide. Almost all congenital cardiac lesions can be successfully treated due to the progress in neonatal surgery and pediatric cardiology with a high likelihood of surviving until adulthood. However, ACHD frequently develop sequelae related to the initial cardiac anomaly. Heart failure (HF) is one of the most common complications associated with a high morbidity and mortality.METHODS: The authors did search the PubMed database regarding relevant content covering publications up to March 2022. Relevant manuscripts were classified according to the impact factor of the journal, being a guideline manuscript, a position paper by a society or a comprehensive review of the current literature.KEY CONTENT AND FINDINGS: Optimal HF treatment remains an unmet need in ACHD. In particular, advanced HF therapy with cardiac resynchronization therapy, ventricular assist devices or organ transplantation is still very different and more specific in ACHD compared to non-ACHD. This review aims to compile international views and evidence from the literatures on the treatment of advanced HF in ACHD. Current challenges, but also the success of different treatment strategies in ACHD are illustrated by clinical cases.CONCLUSIONS: The main finding of the review is that data is still scarce regarding ACHD with advanced HF and international efforts to collect data regarding these patients needed to improve the current standard of care.
AB - BACKGROUND AND OBJECTIVE: The number of adults with congenital heart disease (ACHD) is increasing worldwide. Almost all congenital cardiac lesions can be successfully treated due to the progress in neonatal surgery and pediatric cardiology with a high likelihood of surviving until adulthood. However, ACHD frequently develop sequelae related to the initial cardiac anomaly. Heart failure (HF) is one of the most common complications associated with a high morbidity and mortality.METHODS: The authors did search the PubMed database regarding relevant content covering publications up to March 2022. Relevant manuscripts were classified according to the impact factor of the journal, being a guideline manuscript, a position paper by a society or a comprehensive review of the current literature.KEY CONTENT AND FINDINGS: Optimal HF treatment remains an unmet need in ACHD. In particular, advanced HF therapy with cardiac resynchronization therapy, ventricular assist devices or organ transplantation is still very different and more specific in ACHD compared to non-ACHD. This review aims to compile international views and evidence from the literatures on the treatment of advanced HF in ACHD. Current challenges, but also the success of different treatment strategies in ACHD are illustrated by clinical cases.CONCLUSIONS: The main finding of the review is that data is still scarce regarding ACHD with advanced HF and international efforts to collect data regarding these patients needed to improve the current standard of care.
U2 - 10.21037/cdt-22-230
DO - 10.21037/cdt-22-230
M3 - SCORING: Review article
C2 - 36329959
VL - 12
SP - 727
EP - 743
JO - CARDIOVASC DIAGN THE
JF - CARDIOVASC DIAGN THE
SN - 2223-3652
IS - 5
ER -
