Travel-associated Coxiella burnetii infections: three cases of Q fever with different clinical manifestation.
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Travel-associated Coxiella burnetii infections: three cases of Q fever with different clinical manifestation. / Kobbe, Robin; Kramme, Stefanie; Gocht, Andreas; Werner, Mathias; Lippert, Ute; May, Jürgen; Burchard, Gerd-Dieter.
In: TRAVEL MED INFECT DI, Vol. 5, No. 6, 6, 01.11.2007, p. 374-379.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Travel-associated Coxiella burnetii infections: three cases of Q fever with different clinical manifestation.
AU - Kobbe, Robin
AU - Kramme, Stefanie
AU - Gocht, Andreas
AU - Werner, Mathias
AU - Lippert, Ute
AU - May, Jürgen
AU - Burchard, Gerd-Dieter
PY - 2007/11/1
Y1 - 2007/11/1
N2 - BACKGROUND: Certain activities expose travellers to Coxiella burnetii, the causative agent of acute human Q fever. Awareness of Q fever must be improved, also as a potential imported disease, but delayed seroconversion and serological cross-reactivity complicate the diagnosis. Granulomatous inflammation of liver and bone marrow can be typical histopathological findings. CASE PRESENTATIONS: We present three imported cases of Q fever with different clinical presentations, in which the travel history identified the sources of infection. CONCLUSIONS: Q fever should be suspected in any imported febrile disease of unknown origin. Clinical manifestations are variable and repeated serological testing is mandatory. In some cases diagnostic biopsies might help to establish early diagnosis.
AB - BACKGROUND: Certain activities expose travellers to Coxiella burnetii, the causative agent of acute human Q fever. Awareness of Q fever must be improved, also as a potential imported disease, but delayed seroconversion and serological cross-reactivity complicate the diagnosis. Granulomatous inflammation of liver and bone marrow can be typical histopathological findings. CASE PRESENTATIONS: We present three imported cases of Q fever with different clinical presentations, in which the travel history identified the sources of infection. CONCLUSIONS: Q fever should be suspected in any imported febrile disease of unknown origin. Clinical manifestations are variable and repeated serological testing is mandatory. In some cases diagnostic biopsies might help to establish early diagnosis.
KW - Adult
KW - Animals
KW - Camels
KW - Cattle
KW - Coxiella burnetii
KW - Fever
KW - Humans
KW - Male
KW - Middle Aged
KW - Q Fever
KW - Travel
KW - Zoonoses
U2 - 10.1016/j.tmaid.2007.07.005
DO - 10.1016/j.tmaid.2007.07.005
M3 - SCORING: Journal article
C2 - 17983976
VL - 5
SP - 374
EP - 379
JO - TRAVEL MED INFECT DI
JF - TRAVEL MED INFECT DI
SN - 1477-8939
IS - 6
M1 - 6
ER -