Trastornos conductuales en el deterioro cognitivo leve
Standard
Trastornos conductuales en el deterioro cognitivo leve. / Demey, Ignacio; Zimerman, Máximo; Allegri, Ricardo F; Serrano, Cecilia M; Taragano, Fernando E.
In: Vertex, Vol. 18, No. 74, 74, 2008, p. 252-257.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Trastornos conductuales en el deterioro cognitivo leve
AU - Demey, Ignacio
AU - Zimerman, Máximo
AU - Allegri, Ricardo F
AU - Serrano, Cecilia M
AU - Taragano, Fernando E
PY - 2008
Y1 - 2008
N2 - The mild cognitive impairment (MCI), has emerged as an identifiable condition and in many cases is an intermediate state preceding diagnosable Alzheimer disease (AD) characterized by acquired cognitive deficits, without significant decline in functional activities of daily living. The aim of this study was to determine both the presence and type of neuropsychiatric manifestations in MCI patients and to compare them with both those suffering from mild AD and normal controls. METHODS: 86 subjects were assessed, 27 were classified as having MCI, 39 as having presumable mild AD, and 20 normal controls matched by age and education. The Neuropsychiatric inventory (NPI-Q) was used to assess the neuropsychiatric manifestations. RESULTS: The most common symptoms in the MCI group were irritability (55%), dysphoria (44%), apathy (37%), and anxiety (37%). Statistically significant differences were observed between the MCI and control groups regarding the above mentioned symptoms (p0.05). However, the differences between the MCI and mild AD groups were not found to be statistically significant. CONCLUSION: MCI is associated with a high rate of neuropsychiatric symptoms (irritability, depression, anxiety and apathy). These symptoms have serious adverse consequences and should be considered in diagnosis criteria.
AB - The mild cognitive impairment (MCI), has emerged as an identifiable condition and in many cases is an intermediate state preceding diagnosable Alzheimer disease (AD) characterized by acquired cognitive deficits, without significant decline in functional activities of daily living. The aim of this study was to determine both the presence and type of neuropsychiatric manifestations in MCI patients and to compare them with both those suffering from mild AD and normal controls. METHODS: 86 subjects were assessed, 27 were classified as having MCI, 39 as having presumable mild AD, and 20 normal controls matched by age and education. The Neuropsychiatric inventory (NPI-Q) was used to assess the neuropsychiatric manifestations. RESULTS: The most common symptoms in the MCI group were irritability (55%), dysphoria (44%), apathy (37%), and anxiety (37%). Statistically significant differences were observed between the MCI and control groups regarding the above mentioned symptoms (p0.05). However, the differences between the MCI and mild AD groups were not found to be statistically significant. CONCLUSION: MCI is associated with a high rate of neuropsychiatric symptoms (irritability, depression, anxiety and apathy). These symptoms have serious adverse consequences and should be considered in diagnosis criteria.
KW - Aged
KW - Cognition Disorders
KW - Female
KW - Humans
KW - Male
KW - Mental Disorders
KW - Severity of Illness Index
M3 - SCORING: Zeitschriftenaufsatz
C2 - 18219397
VL - 18
SP - 252
EP - 257
IS - 74
M1 - 74
ER -
