Transperineal reanastomosis for treatment of highly recurrent anastomotic strictures after radical retropubic prostatectomy: extended follow-up

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Transperineal reanastomosis for treatment of highly recurrent anastomotic strictures after radical retropubic prostatectomy: extended follow-up. / Schüttfort, Victor; Dahlem, Roland; Kluth, Luis Alex; Pfalzgraf, Daniel; Rosenbaum, Clemens; Ludwig, Tim Alexander; Fisch, Margit; Reiß, Christoph-Philip.

In: WORLD J UROL, Vol. 35, No. 12, 12.2017, p. 1885-1890.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

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@article{16798edc7f534306b75a9799341b3a92,
title = "Transperineal reanastomosis for treatment of highly recurrent anastomotic strictures after radical retropubic prostatectomy: extended follow-up",
abstract = "OBJECTIVES:To re-evaluate safety and efficacy of transperineal reanastomosis (TPRA) as a viable therapeutic option in highly recurrent anastomotic strictures (AS) after radical retropubic prostatectomy (RRP).METHODS:Retrospective analysis by standardized questionnaire inquiring for recurrence of stricture, stress urinary incontinence (SUI), sexual function, satisfaction, and changes in quality of life (QoL) was performed in all patients undergoing TPRA. Validated questionnaires (ICIQ-UI, EQ-5D, and IPSS) were included.RESULTS:Median follow-up was 45.0 months. The average number of prior operations was 4.69. Success rate was 87% (20/23). Three recurrences were successfully treated via endoscopic means. All patients had urinary incontinence pre-op and post-op. Implantation of an artificial urinary sphincter (AUS) has been performed successfully in 73.9% (17/23). Rate of complications was low (8.7%; 2/23, Clavien-Dindo Grade II + III). EQ-5D-VAS showed a good general state of health (73.5/100). An improvement in QoL was noted in 63.6% (14/22) and patient satisfaction was high (72.7%; 16/22).CONCLUSIONS:This extended follow-up confirms the initial results for TPRA as an excellent treatment option for highly recurrent AS after RRP. Postoperative SUI as a consequence of transsphincteric urethral mobilization can be satisfactorily treated by the implantation of AUS. In case of AS recalcitrant to endoscopic treatment, the described procedure-even though technically challenging-represents a valuable treatment option.",
keywords = "Aftercare, Aged, Anastomosis, Surgical, Constriction, Pathologic, Endoscopy, Germany, Humans, Male, Middle Aged, Postoperative Complications, Prostatectomy, Prostatic Neoplasms, Quality of Life, Reconstructive Surgical Procedures, Recurrence, Reoperation, Surveys and Questionnaires, Journal Article",
author = "Victor Sch{\"u}ttfort and Roland Dahlem and Kluth, {Luis Alex} and Daniel Pfalzgraf and Clemens Rosenbaum and Ludwig, {Tim Alexander} and Margit Fisch and Christoph-Philip Rei{\ss}",
year = "2017",
month = dec,
doi = "10.1007/s00345-017-2067-8",
language = "English",
volume = "35",
pages = "1885--1890",
journal = "WORLD J UROL",
issn = "0724-4983",
publisher = "Springer",
number = "12",

}

RIS

TY - JOUR

T1 - Transperineal reanastomosis for treatment of highly recurrent anastomotic strictures after radical retropubic prostatectomy: extended follow-up

AU - Schüttfort, Victor

AU - Dahlem, Roland

AU - Kluth, Luis Alex

AU - Pfalzgraf, Daniel

AU - Rosenbaum, Clemens

AU - Ludwig, Tim Alexander

AU - Fisch, Margit

AU - Reiß, Christoph-Philip

PY - 2017/12

Y1 - 2017/12

N2 - OBJECTIVES:To re-evaluate safety and efficacy of transperineal reanastomosis (TPRA) as a viable therapeutic option in highly recurrent anastomotic strictures (AS) after radical retropubic prostatectomy (RRP).METHODS:Retrospective analysis by standardized questionnaire inquiring for recurrence of stricture, stress urinary incontinence (SUI), sexual function, satisfaction, and changes in quality of life (QoL) was performed in all patients undergoing TPRA. Validated questionnaires (ICIQ-UI, EQ-5D, and IPSS) were included.RESULTS:Median follow-up was 45.0 months. The average number of prior operations was 4.69. Success rate was 87% (20/23). Three recurrences were successfully treated via endoscopic means. All patients had urinary incontinence pre-op and post-op. Implantation of an artificial urinary sphincter (AUS) has been performed successfully in 73.9% (17/23). Rate of complications was low (8.7%; 2/23, Clavien-Dindo Grade II + III). EQ-5D-VAS showed a good general state of health (73.5/100). An improvement in QoL was noted in 63.6% (14/22) and patient satisfaction was high (72.7%; 16/22).CONCLUSIONS:This extended follow-up confirms the initial results for TPRA as an excellent treatment option for highly recurrent AS after RRP. Postoperative SUI as a consequence of transsphincteric urethral mobilization can be satisfactorily treated by the implantation of AUS. In case of AS recalcitrant to endoscopic treatment, the described procedure-even though technically challenging-represents a valuable treatment option.

AB - OBJECTIVES:To re-evaluate safety and efficacy of transperineal reanastomosis (TPRA) as a viable therapeutic option in highly recurrent anastomotic strictures (AS) after radical retropubic prostatectomy (RRP).METHODS:Retrospective analysis by standardized questionnaire inquiring for recurrence of stricture, stress urinary incontinence (SUI), sexual function, satisfaction, and changes in quality of life (QoL) was performed in all patients undergoing TPRA. Validated questionnaires (ICIQ-UI, EQ-5D, and IPSS) were included.RESULTS:Median follow-up was 45.0 months. The average number of prior operations was 4.69. Success rate was 87% (20/23). Three recurrences were successfully treated via endoscopic means. All patients had urinary incontinence pre-op and post-op. Implantation of an artificial urinary sphincter (AUS) has been performed successfully in 73.9% (17/23). Rate of complications was low (8.7%; 2/23, Clavien-Dindo Grade II + III). EQ-5D-VAS showed a good general state of health (73.5/100). An improvement in QoL was noted in 63.6% (14/22) and patient satisfaction was high (72.7%; 16/22).CONCLUSIONS:This extended follow-up confirms the initial results for TPRA as an excellent treatment option for highly recurrent AS after RRP. Postoperative SUI as a consequence of transsphincteric urethral mobilization can be satisfactorily treated by the implantation of AUS. In case of AS recalcitrant to endoscopic treatment, the described procedure-even though technically challenging-represents a valuable treatment option.

KW - Aftercare

KW - Aged

KW - Anastomosis, Surgical

KW - Constriction, Pathologic

KW - Endoscopy

KW - Germany

KW - Humans

KW - Male

KW - Middle Aged

KW - Postoperative Complications

KW - Prostatectomy

KW - Prostatic Neoplasms

KW - Quality of Life

KW - Reconstructive Surgical Procedures

KW - Recurrence

KW - Reoperation

KW - Surveys and Questionnaires

KW - Journal Article

U2 - 10.1007/s00345-017-2067-8

DO - 10.1007/s00345-017-2067-8

M3 - SCORING: Journal article

C2 - 28674908

VL - 35

SP - 1885

EP - 1890

JO - WORLD J UROL

JF - WORLD J UROL

SN - 0724-4983

IS - 12

ER -