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Topical treatment of tinea pedis using 6% coriander oil in unguentum leniens: a randomized, controlled, comparative pilot study

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Topical treatment of tinea pedis using 6% coriander oil in unguentum leniens: a randomized, controlled, comparative pilot study. / Beikert, F C; Anastasiadou, Z; Fritzen, B; Frank, U; Augustin, M.

In: DERMATOLOGY, Vol. 226, No. 1, 01.01.2013, p. 47-51.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Beikert, FC, Anastasiadou, Z, Fritzen, B, Frank, U & Augustin, M 2013, 'Topical treatment of tinea pedis using 6% coriander oil in unguentum leniens: a randomized, controlled, comparative pilot study', DERMATOLOGY, vol. 226, no. 1, pp. 47-51. https://doi.org/10.1159/000346641

APA

Beikert, F. C., Anastasiadou, Z., Fritzen, B., Frank, U., & Augustin, M. (2013). Topical treatment of tinea pedis using 6% coriander oil in unguentum leniens: a randomized, controlled, comparative pilot study. DERMATOLOGY, 226(1), 47-51. https://doi.org/10.1159/000346641

Vancouver

Beikert FC, Anastasiadou Z, Fritzen B, Frank U, Augustin M. Topical treatment of tinea pedis using 6% coriander oil in unguentum leniens: a randomized, controlled, comparative pilot study. DERMATOLOGY. 2013 Jan 1;226(1):47-51. https://doi.org/10.1159/000346641

Bibtex

@article{6a2b236e8b3f4bc49cf2ce8e4baa779f,
title = "Topical treatment of tinea pedis using 6% coriander oil in unguentum leniens: a randomized, controlled, comparative pilot study",
abstract = "BACKGROUND: The antifungal activity of coriander oil has already been demonstrated in vitro.OBJECTIVE: Evaluation of the efficacy and tolerability of 6% coriander oil in unguentum leniens in the treatment of interdigital tinea pedis. Methods: Half-side comparative pilot study on subjects with symmetric, bilateral interdigital tinea pedis. Active drug and placebo control were applied twice daily on the affected areas, and follow-up visits were performed on days 14 and 28.RESULTS: 40 participants (mean age 52.5 years, 60% male) were included in the study. For 6% coriander oil in unguentum leniens, a highly significant improvement of the clinical signs (p < 0.0001) was observed during the entire observation period; the number of positive fungal cultures also tended to decrease (p = 0.0654). The tolerability of the tested substances was good.CONCLUSION: Coriander oil is effective and well tolerated in the treatment of interdigital tinea pedis.",
keywords = "Administration, Topical, Adult, Aged, Aged, 80 and over, Antifungal Agents, Candida, Coriandrum, Female, Humans, Male, Middle Aged, Ointments, Phytotherapy, Pilot Projects, Plant Oils, Tinea Pedis, Treatment Outcome, Trichophyton, Young Adult",
author = "Beikert, {F C} and Z Anastasiadou and B Fritzen and U Frank and M Augustin",
note = "Copyright {\textcopyright} 2013 S. Karger AG, Basel.",
year = "2013",
month = jan,
day = "1",
doi = "10.1159/000346641",
language = "English",
volume = "226",
pages = "47--51",
journal = "DERMATOLOGY",
issn = "1018-8665",
publisher = "S. Karger AG",
number = "1",

}

RIS

TY - JOUR

T1 - Topical treatment of tinea pedis using 6% coriander oil in unguentum leniens: a randomized, controlled, comparative pilot study

AU - Beikert, F C

AU - Anastasiadou, Z

AU - Fritzen, B

AU - Frank, U

AU - Augustin, M

N1 - Copyright © 2013 S. Karger AG, Basel.

PY - 2013/1/1

Y1 - 2013/1/1

N2 - BACKGROUND: The antifungal activity of coriander oil has already been demonstrated in vitro.OBJECTIVE: Evaluation of the efficacy and tolerability of 6% coriander oil in unguentum leniens in the treatment of interdigital tinea pedis. Methods: Half-side comparative pilot study on subjects with symmetric, bilateral interdigital tinea pedis. Active drug and placebo control were applied twice daily on the affected areas, and follow-up visits were performed on days 14 and 28.RESULTS: 40 participants (mean age 52.5 years, 60% male) were included in the study. For 6% coriander oil in unguentum leniens, a highly significant improvement of the clinical signs (p < 0.0001) was observed during the entire observation period; the number of positive fungal cultures also tended to decrease (p = 0.0654). The tolerability of the tested substances was good.CONCLUSION: Coriander oil is effective and well tolerated in the treatment of interdigital tinea pedis.

AB - BACKGROUND: The antifungal activity of coriander oil has already been demonstrated in vitro.OBJECTIVE: Evaluation of the efficacy and tolerability of 6% coriander oil in unguentum leniens in the treatment of interdigital tinea pedis. Methods: Half-side comparative pilot study on subjects with symmetric, bilateral interdigital tinea pedis. Active drug and placebo control were applied twice daily on the affected areas, and follow-up visits were performed on days 14 and 28.RESULTS: 40 participants (mean age 52.5 years, 60% male) were included in the study. For 6% coriander oil in unguentum leniens, a highly significant improvement of the clinical signs (p < 0.0001) was observed during the entire observation period; the number of positive fungal cultures also tended to decrease (p = 0.0654). The tolerability of the tested substances was good.CONCLUSION: Coriander oil is effective and well tolerated in the treatment of interdigital tinea pedis.

KW - Administration, Topical

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - Antifungal Agents

KW - Candida

KW - Coriandrum

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Ointments

KW - Phytotherapy

KW - Pilot Projects

KW - Plant Oils

KW - Tinea Pedis

KW - Treatment Outcome

KW - Trichophyton

KW - Young Adult

U2 - 10.1159/000346641

DO - 10.1159/000346641

M3 - SCORING: Journal article

C2 - 23466353

VL - 226

SP - 47

EP - 51

JO - DERMATOLOGY

JF - DERMATOLOGY

SN - 1018-8665

IS - 1

ER -