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Tissue microarrays.

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Tissue microarrays. / Simon, Ronald; Mirlacher, Martina; Sauter, Guido.

In: Methods Mol Med, Vol. 114, 2005, p. 257-268.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Simon, R, Mirlacher, M & Sauter, G 2005, 'Tissue microarrays.', Methods Mol Med, vol. 114, pp. 257-268. <http://www.ncbi.nlm.nih.gov/pubmed/16156109?dopt=Citation>

APA

Simon, R., Mirlacher, M., & Sauter, G. (2005). Tissue microarrays. Methods Mol Med, 114, 257-268. http://www.ncbi.nlm.nih.gov/pubmed/16156109?dopt=Citation

Vancouver

Simon R, Mirlacher M, Sauter G. Tissue microarrays. Methods Mol Med. 2005;114:257-268.

Bibtex

@article{176c5626aeb64881becf2d952a666789,
title = "Tissue microarrays.",
abstract = "New high-throughput screening technologies have led to the identification of hundreds of genes with potential roles in cancer or other diseases. For evaluation of promising candidate genes, however, in-situ analysis of high numbers of clinical tissue samples is mandatory. The tissue microarray (TMA) technology greatly facilitates such analysis. In this method minute tissue samples (0.6 mm in diameter) from up to 1000 different tissues can be analyzed on one microscope glass slide. All in-situ methods suitable for histological studies can be applied to TMAs without major changes in protocols, including immunohistochemistry, fluorescence in-situ hybridization, or RNA in-situ hybridization. Because all tissues are analyzed simultaneously with the same batch of reagents, TMA studies provide an unprecedented degree of standardization, speed, and cost efficiency.",
author = "Ronald Simon and Martina Mirlacher and Guido Sauter",
year = "2005",
language = "Deutsch",
volume = "114",
pages = "257--268",

}

RIS

TY - JOUR

T1 - Tissue microarrays.

AU - Simon, Ronald

AU - Mirlacher, Martina

AU - Sauter, Guido

PY - 2005

Y1 - 2005

N2 - New high-throughput screening technologies have led to the identification of hundreds of genes with potential roles in cancer or other diseases. For evaluation of promising candidate genes, however, in-situ analysis of high numbers of clinical tissue samples is mandatory. The tissue microarray (TMA) technology greatly facilitates such analysis. In this method minute tissue samples (0.6 mm in diameter) from up to 1000 different tissues can be analyzed on one microscope glass slide. All in-situ methods suitable for histological studies can be applied to TMAs without major changes in protocols, including immunohistochemistry, fluorescence in-situ hybridization, or RNA in-situ hybridization. Because all tissues are analyzed simultaneously with the same batch of reagents, TMA studies provide an unprecedented degree of standardization, speed, and cost efficiency.

AB - New high-throughput screening technologies have led to the identification of hundreds of genes with potential roles in cancer or other diseases. For evaluation of promising candidate genes, however, in-situ analysis of high numbers of clinical tissue samples is mandatory. The tissue microarray (TMA) technology greatly facilitates such analysis. In this method minute tissue samples (0.6 mm in diameter) from up to 1000 different tissues can be analyzed on one microscope glass slide. All in-situ methods suitable for histological studies can be applied to TMAs without major changes in protocols, including immunohistochemistry, fluorescence in-situ hybridization, or RNA in-situ hybridization. Because all tissues are analyzed simultaneously with the same batch of reagents, TMA studies provide an unprecedented degree of standardization, speed, and cost efficiency.

M3 - SCORING: Zeitschriftenaufsatz

VL - 114

SP - 257

EP - 268

ER -