Thrombus embolization into IVC filters during catheter-directed thrombolysis for proximal deep venous thrombosis
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Thrombus embolization into IVC filters during catheter-directed thrombolysis for proximal deep venous thrombosis. / Kölbel, Tilo; Alhadad, Alaa; Acosta, Stefan; Lindh, Mats; Ivancev, Krasnodar; Gottsäter, Anders.
In: J ENDOVASC THER, Vol. 15, No. 5, 10.2008, p. 605-613.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Thrombus embolization into IVC filters during catheter-directed thrombolysis for proximal deep venous thrombosis
AU - Kölbel, Tilo
AU - Alhadad, Alaa
AU - Acosta, Stefan
AU - Lindh, Mats
AU - Ivancev, Krasnodar
AU - Gottsäter, Anders
PY - 2008/10
Y1 - 2008/10
N2 - PURPOSE: To assess the frequency of embolization into retrievable inferior vena cava (IVC) filters during catheter-directed thrombolysis (CDT) and stent placement for acute iliocaval deep venous thrombosis (DVT).METHODS: Serial phlebograms from 40 patients (28 women; median age 32 years) consecutively treated with CDT for DVT during a 12-year period were retrospectively evaluated for visible emboli in the IVC filter. Clinical and procedural data extracted from a prospectively maintained database were evaluated to identify predictors for embolization into the filter.RESULTS: Visible emboli were found in 18 (45%) patients. Visible embolization to the IVC filter was less frequent in patients with a hypercoagulable disorder (n = 29, 31%) than in patients without a hypercoagulable disorder (n = 11, 69%; OR 0.1, 95% CI 0.02 to 0.56, p = 0.006). No patient developed clinical symptomatic pulmonary embolism or a complication related to the placement or retrieval of the IVC filter.CONCLUSION: Thrombus embolization during CDT is a common phenomenon in patients with proximal DVT. Placement of a retrievable IVC filter during thrombolytic therapy can prevent silent and symptomatic pulmonary embolism.
AB - PURPOSE: To assess the frequency of embolization into retrievable inferior vena cava (IVC) filters during catheter-directed thrombolysis (CDT) and stent placement for acute iliocaval deep venous thrombosis (DVT).METHODS: Serial phlebograms from 40 patients (28 women; median age 32 years) consecutively treated with CDT for DVT during a 12-year period were retrospectively evaluated for visible emboli in the IVC filter. Clinical and procedural data extracted from a prospectively maintained database were evaluated to identify predictors for embolization into the filter.RESULTS: Visible emboli were found in 18 (45%) patients. Visible embolization to the IVC filter was less frequent in patients with a hypercoagulable disorder (n = 29, 31%) than in patients without a hypercoagulable disorder (n = 11, 69%; OR 0.1, 95% CI 0.02 to 0.56, p = 0.006). No patient developed clinical symptomatic pulmonary embolism or a complication related to the placement or retrieval of the IVC filter.CONCLUSION: Thrombus embolization during CDT is a common phenomenon in patients with proximal DVT. Placement of a retrievable IVC filter during thrombolytic therapy can prevent silent and symptomatic pulmonary embolism.
KW - Adult
KW - Catheterization
KW - Embolization, Therapeutic
KW - Female
KW - Humans
KW - Iliac Vein
KW - Male
KW - Retrospective Studies
KW - Stents
KW - Thrombolytic Therapy
KW - Vena Cava Filters
KW - Vena Cava, Inferior
KW - Venous Thrombosis/therapy
KW - Young Adult
U2 - 10.1583/08-2462.1
DO - 10.1583/08-2462.1
M3 - SCORING: Journal article
C2 - 18840047
VL - 15
SP - 605
EP - 613
JO - J ENDOVASC THER
JF - J ENDOVASC THER
SN - 1526-6028
IS - 5
ER -
