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Three-year efficacy and safety of tenofovir disoproxil fumarate treatment for chronic hepatitis B.

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Three-year efficacy and safety of tenofovir disoproxil fumarate treatment for chronic hepatitis B. / Heathcote, E Jenny; Marcellin, Patrick; Buti, Maria; Gane, Edward; Man, De; Robert, A; Krastev, Zahary; Germanidis, George; Lee, Samuel S; Flisiak, Robert; Kaita, Kelly; Manns, Michael; Kotzev, Iskren; Buggisch, Peter; Buggisch, Peter; Weilert, Frank; Kurdas, Oya Ovunc; Shiffman, Mitchell L; Trinh, Huy; Gurel, Selim; Snow-Lampart, Andrea; Borroto-Esoda, Katyna; Mondou, Elsa; Anderson, Jane; Sorbel, Jeff; Rousseau, Franck.

In: GASTROENTEROLOGY, Vol. 140, No. 1, 1, 2011, p. 132-143.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Heathcote, EJ, Marcellin, P, Buti, M, Gane, E, Man, D, Robert, A, Krastev, Z, Germanidis, G, Lee, SS, Flisiak, R, Kaita, K, Manns, M, Kotzev, I, Buggisch, P, Buggisch, P, Weilert, F, Kurdas, OO, Shiffman, ML, Trinh, H, Gurel, S, Snow-Lampart, A, Borroto-Esoda, K, Mondou, E, Anderson, J, Sorbel, J & Rousseau, F 2011, 'Three-year efficacy and safety of tenofovir disoproxil fumarate treatment for chronic hepatitis B.', GASTROENTEROLOGY, vol. 140, no. 1, 1, pp. 132-143. <http://www.ncbi.nlm.nih.gov/pubmed/20955704?dopt=Citation>

APA

Heathcote, E. J., Marcellin, P., Buti, M., Gane, E., Man, D., Robert, A., Krastev, Z., Germanidis, G., Lee, S. S., Flisiak, R., Kaita, K., Manns, M., Kotzev, I., Buggisch, P., Buggisch, P., Weilert, F., Kurdas, O. O., Shiffman, M. L., Trinh, H., ... Rousseau, F. (2011). Three-year efficacy and safety of tenofovir disoproxil fumarate treatment for chronic hepatitis B. GASTROENTEROLOGY, 140(1), 132-143. [1]. http://www.ncbi.nlm.nih.gov/pubmed/20955704?dopt=Citation

Vancouver

Heathcote EJ, Marcellin P, Buti M, Gane E, Man D, Robert A et al. Three-year efficacy and safety of tenofovir disoproxil fumarate treatment for chronic hepatitis B. GASTROENTEROLOGY. 2011;140(1):132-143. 1.

Bibtex

@article{59d31a07a4164949ba1f3519d5b22b79,
title = "Three-year efficacy and safety of tenofovir disoproxil fumarate treatment for chronic hepatitis B.",
abstract = "Tenofovir disoproxil fumarate (TDF), a nucleotide analogue and potent inhibitor of hepatitis B virus (HBV) polymerase, showed superior efficacy to adefovir dipivoxil in treatment of chronic hepatitis B through 48 weeks. We evaluated long-term efficacy and safety of TDF monotherapy in patients with chronic hepatitis B who were positive or negative for hepatitis B e antigen (HBeAg(+) or HBeAg(-)).",
keywords = "Adult, Biopsy, Humans, Male, Female, Middle Aged, Adolescent, Young Adult, Randomized Controlled Trials as Topic, Treatment Outcome, Follow-Up Studies, Antiviral Agents/*therapeutic use, Alanine Transaminase/blood, Adenine/*analogs & derivatives/therapeutic use, DNA, Viral/drug effects, Drug Resistance, Viral/drug effects, Hepatitis B e Antigens/analysis, Hepatitis B virus/drug effects, Hepatitis B, Chronic/*drug therapy/virology, Phosphonic Acids/*therapeutic use, Virus Replication/drug effects, Adult, Biopsy, Humans, Male, Female, Middle Aged, Adolescent, Young Adult, Randomized Controlled Trials as Topic, Treatment Outcome, Follow-Up Studies, Antiviral Agents/*therapeutic use, Alanine Transaminase/blood, Adenine/*analogs & derivatives/therapeutic use, DNA, Viral/drug effects, Drug Resistance, Viral/drug effects, Hepatitis B e Antigens/analysis, Hepatitis B virus/drug effects, Hepatitis B, Chronic/*drug therapy/virology, Phosphonic Acids/*therapeutic use, Virus Replication/drug effects",
author = "Heathcote, {E Jenny} and Patrick Marcellin and Maria Buti and Edward Gane and De Man and A Robert and Zahary Krastev and George Germanidis and Lee, {Samuel S} and Robert Flisiak and Kelly Kaita and Michael Manns and Iskren Kotzev and Peter Buggisch and Peter Buggisch and Frank Weilert and Kurdas, {Oya Ovunc} and Shiffman, {Mitchell L} and Huy Trinh and Selim Gurel and Andrea Snow-Lampart and Katyna Borroto-Esoda and Elsa Mondou and Jane Anderson and Jeff Sorbel and Franck Rousseau",
year = "2011",
language = "English",
volume = "140",
pages = "132--143",
journal = "GASTROENTEROLOGY",
issn = "0016-5085",
publisher = "W.B. Saunders Ltd",
number = "1",

}

RIS

TY - JOUR

T1 - Three-year efficacy and safety of tenofovir disoproxil fumarate treatment for chronic hepatitis B.

AU - Heathcote, E Jenny

AU - Marcellin, Patrick

AU - Buti, Maria

AU - Gane, Edward

AU - Man, De

AU - Robert, A

AU - Krastev, Zahary

AU - Germanidis, George

AU - Lee, Samuel S

AU - Flisiak, Robert

AU - Kaita, Kelly

AU - Manns, Michael

AU - Kotzev, Iskren

AU - Buggisch, Peter

AU - Buggisch, Peter

AU - Weilert, Frank

AU - Kurdas, Oya Ovunc

AU - Shiffman, Mitchell L

AU - Trinh, Huy

AU - Gurel, Selim

AU - Snow-Lampart, Andrea

AU - Borroto-Esoda, Katyna

AU - Mondou, Elsa

AU - Anderson, Jane

AU - Sorbel, Jeff

AU - Rousseau, Franck

PY - 2011

Y1 - 2011

N2 - Tenofovir disoproxil fumarate (TDF), a nucleotide analogue and potent inhibitor of hepatitis B virus (HBV) polymerase, showed superior efficacy to adefovir dipivoxil in treatment of chronic hepatitis B through 48 weeks. We evaluated long-term efficacy and safety of TDF monotherapy in patients with chronic hepatitis B who were positive or negative for hepatitis B e antigen (HBeAg(+) or HBeAg(-)).

AB - Tenofovir disoproxil fumarate (TDF), a nucleotide analogue and potent inhibitor of hepatitis B virus (HBV) polymerase, showed superior efficacy to adefovir dipivoxil in treatment of chronic hepatitis B through 48 weeks. We evaluated long-term efficacy and safety of TDF monotherapy in patients with chronic hepatitis B who were positive or negative for hepatitis B e antigen (HBeAg(+) or HBeAg(-)).

KW - Adult

KW - Biopsy

KW - Humans

KW - Male

KW - Female

KW - Middle Aged

KW - Adolescent

KW - Young Adult

KW - Randomized Controlled Trials as Topic

KW - Treatment Outcome

KW - Follow-Up Studies

KW - Antiviral Agents/therapeutic use

KW - Alanine Transaminase/blood

KW - Adenine/analogs & derivatives/therapeutic use

KW - DNA, Viral/drug effects

KW - Drug Resistance, Viral/drug effects

KW - Hepatitis B e Antigens/analysis

KW - Hepatitis B virus/drug effects

KW - Hepatitis B, Chronic/drug therapy/virology

KW - Phosphonic Acids/therapeutic use

KW - Virus Replication/drug effects

KW - Adult

KW - Biopsy

KW - Humans

KW - Male

KW - Female

KW - Middle Aged

KW - Adolescent

KW - Young Adult

KW - Randomized Controlled Trials as Topic

KW - Treatment Outcome

KW - Follow-Up Studies

KW - Antiviral Agents/therapeutic use

KW - Alanine Transaminase/blood

KW - Adenine/analogs & derivatives/therapeutic use

KW - DNA, Viral/drug effects

KW - Drug Resistance, Viral/drug effects

KW - Hepatitis B e Antigens/analysis

KW - Hepatitis B virus/drug effects

KW - Hepatitis B, Chronic/drug therapy/virology

KW - Phosphonic Acids/therapeutic use

KW - Virus Replication/drug effects

M3 - SCORING: Journal article

VL - 140

SP - 132

EP - 143

JO - GASTROENTEROLOGY

JF - GASTROENTEROLOGY

SN - 0016-5085

IS - 1

M1 - 1

ER -