[Therapy of patients with myeloid leukemia with small doses of cytosine arabinoside]
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[Therapy of patients with myeloid leukemia with small doses of cytosine arabinoside]. / Patterson, D; Kravtsova, V M; Petrova, E M; Zabelina, Tatjana; Balaian, L N.
In: TERAPEVT ARKH, Vol. 59, No. 12, 12, 1987, p. 81-86.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - [Therapy of patients with myeloid leukemia with small doses of cytosine arabinoside]
AU - Patterson, D
AU - Kravtsova, V M
AU - Petrova, E M
AU - Zabelina, Tatjana
AU - Balaian, L N
PY - 1987
Y1 - 1987
N2 - A total of 45 patients were given cytosar and daunorubicin therapy at small doses. Of them 23 patients were with acute nonlymphoblastic leukemia, 12--with hemopoietic dysplasia, and 10--with chronic myeloid leukemia. Cytosar was injected subcutaneously every 12 h at a dose of 10 mg/m2 for 10-25 days, daunorubicin was injected intravenously by drop infusion at a dose of 5 mg/m2. Clinicohematological remission was obtained in 13 patients, clinicohematological improvement in 16. Thus, a positive effect was achieved in 29 patients (64%). The authors provided some data on the influence of small doses of cytosar and daunorubicin on cell maturation in vitro.
AB - A total of 45 patients were given cytosar and daunorubicin therapy at small doses. Of them 23 patients were with acute nonlymphoblastic leukemia, 12--with hemopoietic dysplasia, and 10--with chronic myeloid leukemia. Cytosar was injected subcutaneously every 12 h at a dose of 10 mg/m2 for 10-25 days, daunorubicin was injected intravenously by drop infusion at a dose of 5 mg/m2. Clinicohematological remission was obtained in 13 patients, clinicohematological improvement in 16. Thus, a positive effect was achieved in 29 patients (64%). The authors provided some data on the influence of small doses of cytosar and daunorubicin on cell maturation in vitro.
M3 - SCORING: Zeitschriftenaufsatz
VL - 59
SP - 81
EP - 86
JO - TERAPEVT ARKH
JF - TERAPEVT ARKH
SN - 0040-3660
IS - 12
M1 - 12
ER -