Therapie des metastasierten Prostatakarzinoms im Wandel – neue Daten und offene Fragen
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Therapie des metastasierten Prostatakarzinoms im Wandel – neue Daten und offene Fragen. / Albers, P; Bögemann, M; Machtens, S; Merseburger, A S; Schostak, M; Steuber, T; Wülfing, C; De Santis, M.
In: UROLOGE, Vol. 59, No. 3, 03.2020, p. 307-317.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Therapie des metastasierten Prostatakarzinoms im Wandel – neue Daten und offene Fragen
AU - Albers, P
AU - Bögemann, M
AU - Machtens, S
AU - Merseburger, A S
AU - Schostak, M
AU - Steuber, T
AU - Wülfing, C
AU - De Santis, M
PY - 2020/3
Y1 - 2020/3
N2 - The availability of taxane-based chemotherapy and androgen-receptor-targeted agents (ARTAs) have significantly broadened the therapeutic options for patients with metastatic prostate cancer and may also result in longer patient survival. The therapeutic sequence of ARTAs and taxanes may influence outcome and therefore decisions should be made on an individual basis. This article provides guidance for therapeutic decision-making in daily clinical practice by working out criteria that can be used to support individual therapeutic decisions. The focus is on metastatic castration-naive prostate cancer, oligometastatic disease as well as non-metastatic and metastatic castration-resistant prostate cancer.
AB - The availability of taxane-based chemotherapy and androgen-receptor-targeted agents (ARTAs) have significantly broadened the therapeutic options for patients with metastatic prostate cancer and may also result in longer patient survival. The therapeutic sequence of ARTAs and taxanes may influence outcome and therefore decisions should be made on an individual basis. This article provides guidance for therapeutic decision-making in daily clinical practice by working out criteria that can be used to support individual therapeutic decisions. The focus is on metastatic castration-naive prostate cancer, oligometastatic disease as well as non-metastatic and metastatic castration-resistant prostate cancer.
KW - Androgen Antagonists
KW - Antineoplastic Agents, Hormonal/therapeutic use
KW - Hormone Replacement Therapy
KW - Humans
KW - Male
KW - Molecular Targeted Therapy
KW - Prostate-Specific Antigen/blood
KW - Prostatectomy/methods
KW - Prostatic Neoplasms, Castration-Resistant/blood
KW - Treatment Outcome
U2 - 10.1007/s00120-019-01072-0
DO - 10.1007/s00120-019-01072-0
M3 - SCORING: Zeitschriftenaufsatz
C2 - 31781782
VL - 59
SP - 307
EP - 317
JO - UROLOGE
JF - UROLOGE
SN - 0340-2592
IS - 3
ER -