Therapie des abdominalen Aortenaneurysmas
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Therapie des abdominalen Aortenaneurysmas. / Debus, E S; Carpenter, S W; Tsilimparis, N; Larena-Avellaneda, A; Kölbel, T.
In: INTERNIST, Vol. 54, No. 5, 05.2013, p. 543-551.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Therapie des abdominalen Aortenaneurysmas
AU - Debus, E S
AU - Carpenter, S W
AU - Tsilimparis, N
AU - Larena-Avellaneda, A
AU - Kölbel, T
PY - 2013/5
Y1 - 2013/5
N2 - The treatment of abdominal aortic aneurysms (AAA) has changed significantly since the introduction of endovascular aortic repair (EVAR). In terms of perioperative morbidity and mortality, randomized multicenter trials revealed results in favour of EVAR compared to open reconstruction. However, EVAR is associated with possible late complications caused by endoleaks, stent migration, kinking and/or overstenting of side branches, making life-long follow-up necessary. Since the majority of patients requiring therapy are elderly and exhibit attendant comorbidities, EVAR has become the procedure of choice in those patients with favourable anatomy. Medicamentous and conservative treatment may be relevant in patients with small to medium-sized aneurysms. Since smoking is one of the major risk factors for the development of AAA, all patients should be advised to stop smoking. Studies on long-term statin therapy in patients following surgical AAA repair showed a reduction in both overall and cardiovascular mortality; AAA patients should therefore receive statins for secondary prevention.
AB - The treatment of abdominal aortic aneurysms (AAA) has changed significantly since the introduction of endovascular aortic repair (EVAR). In terms of perioperative morbidity and mortality, randomized multicenter trials revealed results in favour of EVAR compared to open reconstruction. However, EVAR is associated with possible late complications caused by endoleaks, stent migration, kinking and/or overstenting of side branches, making life-long follow-up necessary. Since the majority of patients requiring therapy are elderly and exhibit attendant comorbidities, EVAR has become the procedure of choice in those patients with favourable anatomy. Medicamentous and conservative treatment may be relevant in patients with small to medium-sized aneurysms. Since smoking is one of the major risk factors for the development of AAA, all patients should be advised to stop smoking. Studies on long-term statin therapy in patients following surgical AAA repair showed a reduction in both overall and cardiovascular mortality; AAA patients should therefore receive statins for secondary prevention.
KW - Aortic Aneurysm, Abdominal/diagnosis
KW - Endovascular Procedures/instrumentation
KW - Humans
KW - Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use
U2 - 10.1007/s00108-012-3218-z
DO - 10.1007/s00108-012-3218-z
M3 - SCORING: Zeitschriftenaufsatz
C2 - 23591937
VL - 54
SP - 543
EP - 551
JO - INTERNIST
JF - INTERNIST
SN - 0020-9554
IS - 5
ER -