Therapeutic potential and limitations of new FAK inhibitors in the treatment of cancer.
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Therapeutic potential and limitations of new FAK inhibitors in the treatment of cancer. / Schultze, Alexander; Fiedler, Walter.
In: EXPERT OPIN INV DRUG, Vol. 19, No. 6, 6, 2010, p. 777-788.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Therapeutic potential and limitations of new FAK inhibitors in the treatment of cancer.
AU - Schultze, Alexander
AU - Fiedler, Walter
PY - 2010
Y1 - 2010
N2 - Activation of the non-receptor tyrosine kinase focal adhesion kinase (FAK) has been implicated in progression of multiple mesenchymal and epithelial malignant tumors. FAK plays an important role in regulation of proliferation, migration and apoptosis of neoplastic cells.
AB - Activation of the non-receptor tyrosine kinase focal adhesion kinase (FAK) has been implicated in progression of multiple mesenchymal and epithelial malignant tumors. FAK plays an important role in regulation of proliferation, migration and apoptosis of neoplastic cells.
M3 - SCORING: Zeitschriftenaufsatz
VL - 19
SP - 777
EP - 788
JO - EXPERT OPIN INV DRUG
JF - EXPERT OPIN INV DRUG
SN - 1354-3784
IS - 6
M1 - 6
ER -