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The Value of Circulating Biomarkers in Bicuspid Aortic Valve-Associated Aortopathy

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The Value of Circulating Biomarkers in Bicuspid Aortic Valve-Associated Aortopathy. / Naito, Shiho; Hillebrand, Mathias; Bernhardt, Alexander Martin Justus; Jagodzinski, Annika; Conradi, Lenard; Detter, Christian; Sydow, Karsten; Reichenspurner, Hermann; Kodolitsch, Yskert von; Girdauskas, Evaldas.

In: THORAC CARDIOV SURG, Vol. 66, No. 4, 06.2018, p. 278-286.

Research output: SCORING: Contribution to journal › SCORING: Review article › Research

Harvard

Naito, S, Hillebrand, M, Bernhardt, AMJ, Jagodzinski, A, Conradi, L, Detter, C, Sydow, K, Reichenspurner, H, Kodolitsch, YV & Girdauskas, E 2018, 'The Value of Circulating Biomarkers in Bicuspid Aortic Valve-Associated Aortopathy', THORAC CARDIOV SURG, vol. 66, no. 4, pp. 278-286. https://doi.org/10.1055/s-0036-1583525

APA

Naito, S., Hillebrand, M., Bernhardt, A. M. J., Jagodzinski, A., Conradi, L., Detter, C., Sydow, K., Reichenspurner, H., Kodolitsch, Y. V., & Girdauskas, E. (2018). The Value of Circulating Biomarkers in Bicuspid Aortic Valve-Associated Aortopathy. THORAC CARDIOV SURG, 66(4), 278-286. https://doi.org/10.1055/s-0036-1583525

Vancouver

Naito S, Hillebrand M, Bernhardt AMJ, Jagodzinski A, Conradi L, Detter C et al. The Value of Circulating Biomarkers in Bicuspid Aortic Valve-Associated Aortopathy. THORAC CARDIOV SURG. 2018 Jun;66(4):278-286. https://doi.org/10.1055/s-0036-1583525

Bibtex

@article{7f21873c1c12468db14d2e3eee002e8b,
title = "The Value of Circulating Biomarkers in Bicuspid Aortic Valve-Associated Aortopathy",
abstract = "Traditional risk stratification model of bicuspid aortic valve (BAV) aortopathy is based on measurement of maximal cross-sectional aortic diameter, definition of proximal aortic shape, and aortic stiffness/elasticity parameters. However, conventional imaging-based criteria are unable to provide reliable information regarding the risk stratification in BAV aortopathy, especially considering the heterogeneous nature of BAV disease. Given those limitations of conventional imaging, there is a growing clinical interest to use circulating biomarkers in the screening process for thoracic aortic aneurysms as well as in the risk-assessment algorithms. We aimed to systematically review currently available biomarkers, which may be of value to predict the natural evolution of aortopathy in individuals with BAV.",
keywords = "Aorta/diagnostic imaging, Aortic Aneurysm/blood, Aortic Valve/abnormalities, Bicuspid Aortic Valve Disease, Biomarkers/blood, Blood Vessel Prosthesis Implantation, Clinical Decision-Making, Dilatation, Pathologic, Heart Valve Diseases/complications, Heart Valve Prosthesis Implantation, Humans, Predictive Value of Tests, Prognosis, Risk Factors",
author = "Shiho Naito and Mathias Hillebrand and Bernhardt, {Alexander Martin Justus} and Annika Jagodzinski and Lenard Conradi and Christian Detter and Karsten Sydow and Hermann Reichenspurner and Kodolitsch, {Yskert von} and Evaldas Girdauskas",
note = "Georg Thieme Verlag KG Stuttgart · New York.",
year = "2018",
month = jun,
doi = "10.1055/s-0036-1583525",
language = "English",
volume = "66",
pages = "278--286",
journal = "THORAC CARDIOV SURG",
issn = "0171-6425",
publisher = "Georg Thieme Verlag KG",
number = "4",

}

RIS

TY - JOUR

T1 - The Value of Circulating Biomarkers in Bicuspid Aortic Valve-Associated Aortopathy

AU - Naito, Shiho

AU - Hillebrand, Mathias

AU - Bernhardt, Alexander Martin Justus

AU - Jagodzinski, Annika

AU - Conradi, Lenard

AU - Detter, Christian

AU - Sydow, Karsten

AU - Reichenspurner, Hermann

AU - Kodolitsch, Yskert von

AU - Girdauskas, Evaldas

N1 - Georg Thieme Verlag KG Stuttgart · New York.

PY - 2018/6

Y1 - 2018/6

N2 - Traditional risk stratification model of bicuspid aortic valve (BAV) aortopathy is based on measurement of maximal cross-sectional aortic diameter, definition of proximal aortic shape, and aortic stiffness/elasticity parameters. However, conventional imaging-based criteria are unable to provide reliable information regarding the risk stratification in BAV aortopathy, especially considering the heterogeneous nature of BAV disease. Given those limitations of conventional imaging, there is a growing clinical interest to use circulating biomarkers in the screening process for thoracic aortic aneurysms as well as in the risk-assessment algorithms. We aimed to systematically review currently available biomarkers, which may be of value to predict the natural evolution of aortopathy in individuals with BAV.

AB - Traditional risk stratification model of bicuspid aortic valve (BAV) aortopathy is based on measurement of maximal cross-sectional aortic diameter, definition of proximal aortic shape, and aortic stiffness/elasticity parameters. However, conventional imaging-based criteria are unable to provide reliable information regarding the risk stratification in BAV aortopathy, especially considering the heterogeneous nature of BAV disease. Given those limitations of conventional imaging, there is a growing clinical interest to use circulating biomarkers in the screening process for thoracic aortic aneurysms as well as in the risk-assessment algorithms. We aimed to systematically review currently available biomarkers, which may be of value to predict the natural evolution of aortopathy in individuals with BAV.

KW - Aorta/diagnostic imaging

KW - Aortic Aneurysm/blood

KW - Aortic Valve/abnormalities

KW - Bicuspid Aortic Valve Disease

KW - Biomarkers/blood

KW - Blood Vessel Prosthesis Implantation

KW - Clinical Decision-Making

KW - Dilatation, Pathologic

KW - Heart Valve Diseases/complications

KW - Heart Valve Prosthesis Implantation

KW - Humans

KW - Predictive Value of Tests

KW - Prognosis

KW - Risk Factors

U2 - 10.1055/s-0036-1583525

DO - 10.1055/s-0036-1583525

M3 - SCORING: Review article

C2 - 27148933

VL - 66

SP - 278

EP - 286

JO - THORAC CARDIOV SURG

JF - THORAC CARDIOV SURG

SN - 0171-6425

IS - 4

ER -