Research ExplorerPublicationsThe use of HIV post-exposure prophylaxis in forensic medicin...

The use of HIV post-exposure prophylaxis in forensic medicine following incidents of sexual violence in Hamburg, Germany: a retrospective study

Standard

The use of HIV post-exposure prophylaxis in forensic medicine following incidents of sexual violence in Hamburg, Germany: a retrospective study. / Ebert, Julia; Sperhake, Jan Peter; Degen, Olaf; Schröder, Ann Sophie.

In: FORENSIC SCI MED PAT, Vol. 14, No. 3, 09.2018, p. 332-341.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Ebert, J, Sperhake, JP, Degen, O & Schröder, AS 2018, 'The use of HIV post-exposure prophylaxis in forensic medicine following incidents of sexual violence in Hamburg, Germany: a retrospective study', FORENSIC SCI MED PAT, vol. 14, no. 3, pp. 332-341. https://doi.org/10.1007/s12024-018-9985-7

APA

Ebert, J., Sperhake, J. P., Degen, O., & Schröder, A. S. (2018). The use of HIV post-exposure prophylaxis in forensic medicine following incidents of sexual violence in Hamburg, Germany: a retrospective study. FORENSIC SCI MED PAT, 14(3), 332-341. https://doi.org/10.1007/s12024-018-9985-7

Vancouver

Ebert J, Sperhake JP, Degen O, Schröder AS. The use of HIV post-exposure prophylaxis in forensic medicine following incidents of sexual violence in Hamburg, Germany: a retrospective study. FORENSIC SCI MED PAT. 2018 Sep;14(3):332-341. https://doi.org/10.1007/s12024-018-9985-7

Bibtex

@article{90a43cfa1b214622913fb5d5f7f239d4,
title = "The use of HIV post-exposure prophylaxis in forensic medicine following incidents of sexual violence in Hamburg, Germany: a retrospective study",
abstract = "In Hamburg, Germany, the initiation of HIV post-exposure prophylaxis (HIV PEP) in cases of sexual violence is often carried out by forensic medical specialists (FMS) using the city's unique Hamburg Model. FMS-provided three-day HIV PEP starter packs include a combination of raltegravir and emtricitabine/tenofovir. This study aimed to investigate the practice of offering HIV PEP, reasons for discontinuing treatment, patient compliance, and whether or not potential perpetrators were tested for HIV. We conducted a retrospective study of forensic clinical examinations carried out by the Hamburg Department of Legal Medicine following incidents of sexual violence from 2009 to 2016. One thousand two hundred eighteen incidents of sexual violence were reviewed. In 18% of these cases, HIV PEP was initially prescribed by the FMS. HIV PEP indication depended on the examination occurring within 24 h after the incident, no/unknown condom use, the occurrence of ejaculation, the presence of any injury, and the perpetrator being from population at high risk for HIV. Half of the HIV PEP recipients returned for a reevaluation of the HIV PEP indication by an infectious disease specialist, and just 16% completed the full month of treatment. Only 131 potential perpetrators were tested for HIV, with one found to be HIV positive. No HIV seroconversion was registered among the study sample. Provision of HIV PEP by an FMS after sexual assault ensures appropriate and prompt care for victims. However, patient compliance and completion rates are low. HIV testing of perpetrators must be carried out much more rigorously.",
keywords = "Adolescent, Adult, Aged, Aged, 80 and over, Anti-HIV Agents, Child, Child, Preschool, Emtricitabine, Female, Germany, HIV Infections, Humans, Male, Medication Adherence, Middle Aged, Post-Exposure Prophylaxis, Raltegravir Potassium, Retrospective Studies, Sex Offenses, Tenofovir, Young Adult, Journal Article",
author = "Julia Ebert and Sperhake, {Jan Peter} and Olaf Degen and Schr{\"o}der, {Ann Sophie}",
year = "2018",
month = sep,
doi = "10.1007/s12024-018-9985-7",
language = "English",
volume = "14",
pages = "332--341",
journal = "FORENSIC SCI MED PAT",
issn = "1547-769X",
publisher = "Humana Press",
number = "3",

}

RIS

TY - JOUR

T1 - The use of HIV post-exposure prophylaxis in forensic medicine following incidents of sexual violence in Hamburg, Germany: a retrospective study

AU - Ebert, Julia

AU - Sperhake, Jan Peter

AU - Degen, Olaf

AU - Schröder, Ann Sophie

PY - 2018/9

Y1 - 2018/9

N2 - In Hamburg, Germany, the initiation of HIV post-exposure prophylaxis (HIV PEP) in cases of sexual violence is often carried out by forensic medical specialists (FMS) using the city's unique Hamburg Model. FMS-provided three-day HIV PEP starter packs include a combination of raltegravir and emtricitabine/tenofovir. This study aimed to investigate the practice of offering HIV PEP, reasons for discontinuing treatment, patient compliance, and whether or not potential perpetrators were tested for HIV. We conducted a retrospective study of forensic clinical examinations carried out by the Hamburg Department of Legal Medicine following incidents of sexual violence from 2009 to 2016. One thousand two hundred eighteen incidents of sexual violence were reviewed. In 18% of these cases, HIV PEP was initially prescribed by the FMS. HIV PEP indication depended on the examination occurring within 24 h after the incident, no/unknown condom use, the occurrence of ejaculation, the presence of any injury, and the perpetrator being from population at high risk for HIV. Half of the HIV PEP recipients returned for a reevaluation of the HIV PEP indication by an infectious disease specialist, and just 16% completed the full month of treatment. Only 131 potential perpetrators were tested for HIV, with one found to be HIV positive. No HIV seroconversion was registered among the study sample. Provision of HIV PEP by an FMS after sexual assault ensures appropriate and prompt care for victims. However, patient compliance and completion rates are low. HIV testing of perpetrators must be carried out much more rigorously.

AB - In Hamburg, Germany, the initiation of HIV post-exposure prophylaxis (HIV PEP) in cases of sexual violence is often carried out by forensic medical specialists (FMS) using the city's unique Hamburg Model. FMS-provided three-day HIV PEP starter packs include a combination of raltegravir and emtricitabine/tenofovir. This study aimed to investigate the practice of offering HIV PEP, reasons for discontinuing treatment, patient compliance, and whether or not potential perpetrators were tested for HIV. We conducted a retrospective study of forensic clinical examinations carried out by the Hamburg Department of Legal Medicine following incidents of sexual violence from 2009 to 2016. One thousand two hundred eighteen incidents of sexual violence were reviewed. In 18% of these cases, HIV PEP was initially prescribed by the FMS. HIV PEP indication depended on the examination occurring within 24 h after the incident, no/unknown condom use, the occurrence of ejaculation, the presence of any injury, and the perpetrator being from population at high risk for HIV. Half of the HIV PEP recipients returned for a reevaluation of the HIV PEP indication by an infectious disease specialist, and just 16% completed the full month of treatment. Only 131 potential perpetrators were tested for HIV, with one found to be HIV positive. No HIV seroconversion was registered among the study sample. Provision of HIV PEP by an FMS after sexual assault ensures appropriate and prompt care for victims. However, patient compliance and completion rates are low. HIV testing of perpetrators must be carried out much more rigorously.

KW - Adolescent

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - Anti-HIV Agents

KW - Child

KW - Child, Preschool

KW - Emtricitabine

KW - Female

KW - Germany

KW - HIV Infections

KW - Humans

KW - Male

KW - Medication Adherence

KW - Middle Aged

KW - Post-Exposure Prophylaxis

KW - Raltegravir Potassium

KW - Retrospective Studies

KW - Sex Offenses

KW - Tenofovir

KW - Young Adult

KW - Journal Article

U2 - 10.1007/s12024-018-9985-7

DO - 10.1007/s12024-018-9985-7

M3 - SCORING: Journal article

C2 - 29777425

VL - 14

SP - 332

EP - 341

JO - FORENSIC SCI MED PAT

JF - FORENSIC SCI MED PAT

SN - 1547-769X

IS - 3

ER -