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The use of extracorporeal carbon dioxide removal to avoid intubation in patients failing non-invasive ventilation--a cost analysis

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The use of extracorporeal carbon dioxide removal to avoid intubation in patients failing non-invasive ventilation--a cost analysis. / Braune, Stephan; Burchardi, Hilmar; Engel, Markus; Nierhaus, Axel; Ebelt, Henning; Metschke, Maria; Rosseau, Simone; Kluge, Stefan.

In: BMC ANESTHESIOL, Vol. 15, 2015, p. 160.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Braune, S, Burchardi, H, Engel, M, Nierhaus, A, Ebelt, H, Metschke, M, Rosseau, S & Kluge, S 2015, 'The use of extracorporeal carbon dioxide removal to avoid intubation in patients failing non-invasive ventilation--a cost analysis', BMC ANESTHESIOL, vol. 15, pp. 160. https://doi.org/10.1186/s12871-015-0139-0

APA

Braune, S., Burchardi, H., Engel, M., Nierhaus, A., Ebelt, H., Metschke, M., Rosseau, S., & Kluge, S. (2015). The use of extracorporeal carbon dioxide removal to avoid intubation in patients failing non-invasive ventilation--a cost analysis. BMC ANESTHESIOL, 15, 160. https://doi.org/10.1186/s12871-015-0139-0

Vancouver

Braune S, Burchardi H, Engel M, Nierhaus A, Ebelt H, Metschke M et al. The use of extracorporeal carbon dioxide removal to avoid intubation in patients failing non-invasive ventilation--a cost analysis. BMC ANESTHESIOL. 2015;15:160. https://doi.org/10.1186/s12871-015-0139-0

Bibtex

@article{d6a007dea59247828482c9f5fc7f5919,
title = "The use of extracorporeal carbon dioxide removal to avoid intubation in patients failing non-invasive ventilation--a cost analysis",
abstract = "BACKGROUND: To evaluate the economic implications of the pre-emptive use of extracorporeal carbon dioxide removal (ECCO2R) to avoid invasive mechanical ventilation (IMV) in patients with hypercapnic ventilatory insufficiency failing non-invasive ventilation (NIV).METHODS: Retrospective ancillary cost analysis of data extracted from a recently published multicentre case-control-study (n = 42) on the use of arterio-venous ECCO2R to avoid IMV in patients with acute on chronic ventilatory failure. Cost calculations were based on average daily treatment costs for intensive care unit (ICU) and normal medical wards as well as on the specific costs of the ECCO2R system.RESULTS: In the group treated with ECCO2R IMV was avoided in 90 % of cases and mean hospital length of stay (LOS) was shorter than in the matched control group treated with IMV (23.0 vs. 42.0 days). The overall average hospital treatment costs did not differ between the two groups (41.134 vs. 39.366 €, p = 0.8). A subgroup analysis of patients with chronic obstructive pulmonary disease (COPD) revealed significantly lower median ICU length of stay (11.0 vs. 35.0 days), hospital length of stay (17.5 vs. 51.5 days) and treatment costs for the ECCO2R group (19.610 vs. 46.552 €, p = 0.01).CONCLUSIONS: Additional costs for the use of arterio-venous ECCO2R to avoid IMV in patients with acute-on-chronic ventilatory insufficiency failing NIV may be offset by a cost reducing effect of a shorter length of ICU and hospital stay.",
author = "Stephan Braune and Hilmar Burchardi and Markus Engel and Axel Nierhaus and Henning Ebelt and Maria Metschke and Simone Rosseau and Stefan Kluge",
year = "2015",
doi = "10.1186/s12871-015-0139-0",
language = "English",
volume = "15",
pages = "160",
journal = "BMC ANESTHESIOL",
issn = "1471-2253",
publisher = "BioMed Central Ltd.",

}

RIS

TY - JOUR

T1 - The use of extracorporeal carbon dioxide removal to avoid intubation in patients failing non-invasive ventilation--a cost analysis

AU - Braune, Stephan

AU - Burchardi, Hilmar

AU - Engel, Markus

AU - Nierhaus, Axel

AU - Ebelt, Henning

AU - Metschke, Maria

AU - Rosseau, Simone

AU - Kluge, Stefan

PY - 2015

Y1 - 2015

N2 - BACKGROUND: To evaluate the economic implications of the pre-emptive use of extracorporeal carbon dioxide removal (ECCO2R) to avoid invasive mechanical ventilation (IMV) in patients with hypercapnic ventilatory insufficiency failing non-invasive ventilation (NIV).METHODS: Retrospective ancillary cost analysis of data extracted from a recently published multicentre case-control-study (n = 42) on the use of arterio-venous ECCO2R to avoid IMV in patients with acute on chronic ventilatory failure. Cost calculations were based on average daily treatment costs for intensive care unit (ICU) and normal medical wards as well as on the specific costs of the ECCO2R system.RESULTS: In the group treated with ECCO2R IMV was avoided in 90 % of cases and mean hospital length of stay (LOS) was shorter than in the matched control group treated with IMV (23.0 vs. 42.0 days). The overall average hospital treatment costs did not differ between the two groups (41.134 vs. 39.366 €, p = 0.8). A subgroup analysis of patients with chronic obstructive pulmonary disease (COPD) revealed significantly lower median ICU length of stay (11.0 vs. 35.0 days), hospital length of stay (17.5 vs. 51.5 days) and treatment costs for the ECCO2R group (19.610 vs. 46.552 €, p = 0.01).CONCLUSIONS: Additional costs for the use of arterio-venous ECCO2R to avoid IMV in patients with acute-on-chronic ventilatory insufficiency failing NIV may be offset by a cost reducing effect of a shorter length of ICU and hospital stay.

AB - BACKGROUND: To evaluate the economic implications of the pre-emptive use of extracorporeal carbon dioxide removal (ECCO2R) to avoid invasive mechanical ventilation (IMV) in patients with hypercapnic ventilatory insufficiency failing non-invasive ventilation (NIV).METHODS: Retrospective ancillary cost analysis of data extracted from a recently published multicentre case-control-study (n = 42) on the use of arterio-venous ECCO2R to avoid IMV in patients with acute on chronic ventilatory failure. Cost calculations were based on average daily treatment costs for intensive care unit (ICU) and normal medical wards as well as on the specific costs of the ECCO2R system.RESULTS: In the group treated with ECCO2R IMV was avoided in 90 % of cases and mean hospital length of stay (LOS) was shorter than in the matched control group treated with IMV (23.0 vs. 42.0 days). The overall average hospital treatment costs did not differ between the two groups (41.134 vs. 39.366 €, p = 0.8). A subgroup analysis of patients with chronic obstructive pulmonary disease (COPD) revealed significantly lower median ICU length of stay (11.0 vs. 35.0 days), hospital length of stay (17.5 vs. 51.5 days) and treatment costs for the ECCO2R group (19.610 vs. 46.552 €, p = 0.01).CONCLUSIONS: Additional costs for the use of arterio-venous ECCO2R to avoid IMV in patients with acute-on-chronic ventilatory insufficiency failing NIV may be offset by a cost reducing effect of a shorter length of ICU and hospital stay.

U2 - 10.1186/s12871-015-0139-0

DO - 10.1186/s12871-015-0139-0

M3 - SCORING: Journal article

C2 - 26537233

VL - 15

SP - 160

JO - BMC ANESTHESIOL

JF - BMC ANESTHESIOL

SN - 1471-2253

ER -