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The significance of ST-elevation in aVL in anterolateral myocardial infarction: An assessment by cardiac magnetic resonance imaging

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The significance of ST-elevation in aVL in anterolateral myocardial infarction: An assessment by cardiac magnetic resonance imaging. / Allencherril, Joseph; Fakhri, Yama; Engblom, Henrik; Heiberg, Einar; Carlsson, Marcus; Dubois-Rande, Jean-Luc; Halvorsen, Sigrun; Hall, Trygve S; Larsen, Alf-Inge; Jensen, Svend Eggert; Arheden, Hakan; Atar, Dan; Clemmensen, Peter; Ripa, Maria Sejersten; Birnbaum, Yochai.

In: ANN NONINVAS ELECTRO, Vol. 23, No. 6, 11.2018, p. e12580.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Allencherril, J, Fakhri, Y, Engblom, H, Heiberg, E, Carlsson, M, Dubois-Rande, J-L, Halvorsen, S, Hall, TS, Larsen, A-I, Jensen, SE, Arheden, H, Atar, D, Clemmensen, P, Ripa, MS & Birnbaum, Y 2018, 'The significance of ST-elevation in aVL in anterolateral myocardial infarction: An assessment by cardiac magnetic resonance imaging', ANN NONINVAS ELECTRO, vol. 23, no. 6, pp. e12580. https://doi.org/10.1111/anec.12580

APA

Allencherril, J., Fakhri, Y., Engblom, H., Heiberg, E., Carlsson, M., Dubois-Rande, J-L., Halvorsen, S., Hall, T. S., Larsen, A-I., Jensen, S. E., Arheden, H., Atar, D., Clemmensen, P., Ripa, M. S., & Birnbaum, Y. (2018). The significance of ST-elevation in aVL in anterolateral myocardial infarction: An assessment by cardiac magnetic resonance imaging. ANN NONINVAS ELECTRO, 23(6), e12580. https://doi.org/10.1111/anec.12580

Vancouver

Allencherril J, Fakhri Y, Engblom H, Heiberg E, Carlsson M, Dubois-Rande J-L et al. The significance of ST-elevation in aVL in anterolateral myocardial infarction: An assessment by cardiac magnetic resonance imaging. ANN NONINVAS ELECTRO. 2018 Nov;23(6):e12580. https://doi.org/10.1111/anec.12580

Bibtex

@article{124f8c37b17a4fa0b9efcd49888f13d8,
title = "The significance of ST-elevation in aVL in anterolateral myocardial infarction: An assessment by cardiac magnetic resonance imaging",
abstract = "BACKGROUND: Anterolateral myocardial infarction (MI) is traditionally defined on the electrocardiogram by ST-elevation (STE) in I, aVL, and the precordial leads. Traditional literature holds STE in lead aVL to be associated with occlusion proximal to the first diagonal branch of the left anterior descending coronary artery. However, concomitant ischemia of the inferior myocardium may theoretically lead to attenuation of STE in aVL. We compared segmental distribution of myocardial area at risk (MaR) in patients with and without STE in aVL.METHODS: We identified patients in the MITOCARE study presenting with a first acute MI and new STE in two contiguous anterior leads from V1 to V6 , with or without aVL STE. Patients underwent cardiac magnetic resonance imaging 3-5 days after acute infarction for quantitative assessment of MaR.RESULTS: A total of 32 patients met inclusion criteria; 13 patients with and 19 without STE in lead aVL. MaR > 20% at the basal anterior segment was seen in 54% of patients with aVL STE, and 11% of those without (p = 0.011). MaR > 20% at the apical inferior segment was seen in 62% and 95% of patients with and without aVL STE, respectively (p = 0.029). The total MaR was not different between groups (44% ± 10% and 39% ± 8.3% respectively, p = 0.15).CONCLUSION: Patients with anterior STEMI and concomitant STE in aVL have less MaR in the apical inferior segment and more MaR in the basal anterior segment.",
keywords = "Aged, Anterior Wall Myocardial Infarction/diagnostic imaging, Coronary Stenosis/complications, Denmark, Double-Blind Method, Electrocardiography/methods, Female, Gadolinium, Humans, Magnetic Resonance Imaging, Cine/methods, Male, Middle Aged, Prognosis, Radiographic Image Enhancement, ST Elevation Myocardial Infarction/diagnostic imaging, Sensitivity and Specificity, Severity of Illness Index, Survival Analysis",
author = "Joseph Allencherril and Yama Fakhri and Henrik Engblom and Einar Heiberg and Marcus Carlsson and Jean-Luc Dubois-Rande and Sigrun Halvorsen and Hall, {Trygve S} and Alf-Inge Larsen and Jensen, {Svend Eggert} and Hakan Arheden and Dan Atar and Peter Clemmensen and Ripa, {Maria Sejersten} and Yochai Birnbaum",
note = "{\textcopyright} 2018 Wiley Periodicals, Inc.",
year = "2018",
month = nov,
doi = "10.1111/anec.12580",
language = "English",
volume = "23",
pages = "e12580",
journal = "ANN NONINVAS ELECTRO",
issn = "1082-720X",
publisher = "Wiley-Blackwell",
number = "6",

}

RIS

TY - JOUR

T1 - The significance of ST-elevation in aVL in anterolateral myocardial infarction: An assessment by cardiac magnetic resonance imaging

AU - Allencherril, Joseph

AU - Fakhri, Yama

AU - Engblom, Henrik

AU - Heiberg, Einar

AU - Carlsson, Marcus

AU - Dubois-Rande, Jean-Luc

AU - Halvorsen, Sigrun

AU - Hall, Trygve S

AU - Larsen, Alf-Inge

AU - Jensen, Svend Eggert

AU - Arheden, Hakan

AU - Atar, Dan

AU - Clemmensen, Peter

AU - Ripa, Maria Sejersten

AU - Birnbaum, Yochai

N1 - © 2018 Wiley Periodicals, Inc.

PY - 2018/11

Y1 - 2018/11

N2 - BACKGROUND: Anterolateral myocardial infarction (MI) is traditionally defined on the electrocardiogram by ST-elevation (STE) in I, aVL, and the precordial leads. Traditional literature holds STE in lead aVL to be associated with occlusion proximal to the first diagonal branch of the left anterior descending coronary artery. However, concomitant ischemia of the inferior myocardium may theoretically lead to attenuation of STE in aVL. We compared segmental distribution of myocardial area at risk (MaR) in patients with and without STE in aVL.METHODS: We identified patients in the MITOCARE study presenting with a first acute MI and new STE in two contiguous anterior leads from V1 to V6 , with or without aVL STE. Patients underwent cardiac magnetic resonance imaging 3-5 days after acute infarction for quantitative assessment of MaR.RESULTS: A total of 32 patients met inclusion criteria; 13 patients with and 19 without STE in lead aVL. MaR > 20% at the basal anterior segment was seen in 54% of patients with aVL STE, and 11% of those without (p = 0.011). MaR > 20% at the apical inferior segment was seen in 62% and 95% of patients with and without aVL STE, respectively (p = 0.029). The total MaR was not different between groups (44% ± 10% and 39% ± 8.3% respectively, p = 0.15).CONCLUSION: Patients with anterior STEMI and concomitant STE in aVL have less MaR in the apical inferior segment and more MaR in the basal anterior segment.

AB - BACKGROUND: Anterolateral myocardial infarction (MI) is traditionally defined on the electrocardiogram by ST-elevation (STE) in I, aVL, and the precordial leads. Traditional literature holds STE in lead aVL to be associated with occlusion proximal to the first diagonal branch of the left anterior descending coronary artery. However, concomitant ischemia of the inferior myocardium may theoretically lead to attenuation of STE in aVL. We compared segmental distribution of myocardial area at risk (MaR) in patients with and without STE in aVL.METHODS: We identified patients in the MITOCARE study presenting with a first acute MI and new STE in two contiguous anterior leads from V1 to V6 , with or without aVL STE. Patients underwent cardiac magnetic resonance imaging 3-5 days after acute infarction for quantitative assessment of MaR.RESULTS: A total of 32 patients met inclusion criteria; 13 patients with and 19 without STE in lead aVL. MaR > 20% at the basal anterior segment was seen in 54% of patients with aVL STE, and 11% of those without (p = 0.011). MaR > 20% at the apical inferior segment was seen in 62% and 95% of patients with and without aVL STE, respectively (p = 0.029). The total MaR was not different between groups (44% ± 10% and 39% ± 8.3% respectively, p = 0.15).CONCLUSION: Patients with anterior STEMI and concomitant STE in aVL have less MaR in the apical inferior segment and more MaR in the basal anterior segment.

KW - Aged

KW - Anterior Wall Myocardial Infarction/diagnostic imaging

KW - Coronary Stenosis/complications

KW - Denmark

KW - Double-Blind Method

KW - Electrocardiography/methods

KW - Female

KW - Gadolinium

KW - Humans

KW - Magnetic Resonance Imaging, Cine/methods

KW - Male

KW - Middle Aged

KW - Prognosis

KW - Radiographic Image Enhancement

KW - ST Elevation Myocardial Infarction/diagnostic imaging

KW - Sensitivity and Specificity

KW - Severity of Illness Index

KW - Survival Analysis

U2 - 10.1111/anec.12580

DO - 10.1111/anec.12580

M3 - SCORING: Journal article

C2 - 29971868

VL - 23

SP - e12580

JO - ANN NONINVAS ELECTRO

JF - ANN NONINVAS ELECTRO

SN - 1082-720X

IS - 6

ER -