The risk of non-sentinel metastases in primary breast cancer.

Ingo G Bauerfeind; Steffen Kahlert; Isabelle Himsl; Yevgenia Sorokina; Ina M Ruehl; Annette Lebeau; Reiner Linke; Michael Untch; Klaus Friese

The risk of non-sentinel metastases in primary breast cancer.

Standard

The risk of non-sentinel metastases in primary breast cancer. / Bauerfeind, Ingo G; Kahlert, Steffen; Himsl, Isabelle; Sorokina, Yevgenia; Ruehl, Ina M; Lebeau, Annette; Linke, Reiner; Untch, Michael; Friese, Klaus.

In: ANTICANCER RES, Vol. 27, No. 4, 4, 2007, p. 1929-1932.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Bauerfeind, IG, Kahlert, S, Himsl, I, Sorokina, Y, Ruehl, IM, Lebeau, A, Linke, R, Untch, M & Friese, K 2007, 'The risk of non-sentinel metastases in primary breast cancer.', ANTICANCER RES, vol. 27, no. 4, 4, pp. 1929-1932. <http://www.ncbi.nlm.nih.gov/pubmed/17649798?dopt=Citation>

APA

Bauerfeind, I. G., Kahlert, S., Himsl, I., Sorokina, Y., Ruehl, I. M., Lebeau, A., Linke, R., Untch, M., & Friese, K. (2007). The risk of non-sentinel metastases in primary breast cancer. ANTICANCER RES, 27(4), 1929-1932. [4]. http://www.ncbi.nlm.nih.gov/pubmed/17649798?dopt=Citation

Vancouver

Bauerfeind IG, Kahlert S, Himsl I, Sorokina Y, Ruehl IM, Lebeau A et al. The risk of non-sentinel metastases in primary breast cancer. ANTICANCER RES. 2007;27(4):1929-1932. 4.

Bibtex

@article{33d66f69fa8b497c8ce9e39332838bd5,

title = "The risk of non-sentinel metastases in primary breast cancer.",

abstract = "BACKGROUND: Sentinel node biopsy (SNB) has been established as standard of surgical care in primary breast cancer. If the sentinel node (SN) is negative, axillary dissection (ALND) is not necessary, but if the SN is positive ALND is warranted. This analysis evaluated associated risk factors for non-sentinel metastases in the case of a positive SN. PATIENTS AND METHODS: A retrospective analysis of all SNB performed between 10/1999 and 07/2005 was carried out. RESULTS: A total of 406 patients were included: 214 patients (51%) had SNB with ALND while 197 patients (49%) had SNB only. In 41 of 109 nodal-positive patients, the SN was the only nodal metastasis. In the multivariate analysis, the number of positive SN and the presence of lymphatic vessel infiltration were significant risk factors for additional non-sentinel metastases (p = 0.05 and 0.047, respectively). The risk for non-sentinel metastases was 25.9% without and 59.2% with these risk factors, respectively. CONCLUSION: If the SN is positive, ALND remains obligatory.",

author = "Bauerfeind, {Ingo G} and Steffen Kahlert and Isabelle Himsl and Yevgenia Sorokina and Ruehl, {Ina M} and Annette Lebeau and Reiner Linke and Michael Untch and Klaus Friese",

year = "2007",

language = "Deutsch",

volume = "27",

pages = "1929--1932",

journal = "ANTICANCER RES",

issn = "0250-7005",

publisher = "International Institute of Anticancer Research",

number = "4",

}

RIS

TY - JOUR

T1 - The risk of non-sentinel metastases in primary breast cancer.

AU - Bauerfeind, Ingo G

AU - Kahlert, Steffen

AU - Himsl, Isabelle

AU - Sorokina, Yevgenia

AU - Ruehl, Ina M

AU - Lebeau, Annette

AU - Linke, Reiner

AU - Untch, Michael

AU - Friese, Klaus

PY - 2007

Y1 - 2007

N2 - BACKGROUND: Sentinel node biopsy (SNB) has been established as standard of surgical care in primary breast cancer. If the sentinel node (SN) is negative, axillary dissection (ALND) is not necessary, but if the SN is positive ALND is warranted. This analysis evaluated associated risk factors for non-sentinel metastases in the case of a positive SN. PATIENTS AND METHODS: A retrospective analysis of all SNB performed between 10/1999 and 07/2005 was carried out. RESULTS: A total of 406 patients were included: 214 patients (51%) had SNB with ALND while 197 patients (49%) had SNB only. In 41 of 109 nodal-positive patients, the SN was the only nodal metastasis. In the multivariate analysis, the number of positive SN and the presence of lymphatic vessel infiltration were significant risk factors for additional non-sentinel metastases (p = 0.05 and 0.047, respectively). The risk for non-sentinel metastases was 25.9% without and 59.2% with these risk factors, respectively. CONCLUSION: If the SN is positive, ALND remains obligatory.

AB - BACKGROUND: Sentinel node biopsy (SNB) has been established as standard of surgical care in primary breast cancer. If the sentinel node (SN) is negative, axillary dissection (ALND) is not necessary, but if the SN is positive ALND is warranted. This analysis evaluated associated risk factors for non-sentinel metastases in the case of a positive SN. PATIENTS AND METHODS: A retrospective analysis of all SNB performed between 10/1999 and 07/2005 was carried out. RESULTS: A total of 406 patients were included: 214 patients (51%) had SNB with ALND while 197 patients (49%) had SNB only. In 41 of 109 nodal-positive patients, the SN was the only nodal metastasis. In the multivariate analysis, the number of positive SN and the presence of lymphatic vessel infiltration were significant risk factors for additional non-sentinel metastases (p = 0.05 and 0.047, respectively). The risk for non-sentinel metastases was 25.9% without and 59.2% with these risk factors, respectively. CONCLUSION: If the SN is positive, ALND remains obligatory.

M3 - SCORING: Zeitschriftenaufsatz

VL - 27

SP - 1929

EP - 1932

JO - ANTICANCER RES

JF - ANTICANCER RES

SN - 0250-7005

IS - 4

M1 - 4

ER -