The neurofilament heavy chain (NfH) in the cerebrospinal fluid diagnosis of Alzheimer's disease.

  • Johannes Brettschneider
  • Axel Petzold
  • Daniel Schöttle
  • Annett Claus
  • Matthias Riepe
  • Hayrettin Tumani

Abstract

Attempting to improve the cerebrospinal fluid (CSF) diagnosis of Alzheimer's disease (AD), the neurofilament heavy chain isoform, NfH(SMI35) was compared to other CSF markers [total tau, phospho-tau, amyloid beta 1-42 (Abeta42), the ratio of amyloid beta fragments Abeta42/Abeta40 (Abeta ratio)].

Bibliographical data

Original languageGerman
Article number5-6
ISSN1420-8008
Publication statusPublished - 2006
pubmed 16484807