The neural correlates of tic inhibition in Gilles de la Tourette syndrome
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The neural correlates of tic inhibition in Gilles de la Tourette syndrome. / Ganos, Christos; Kahl, Ursula; Brandt, Valerie; Schunke, Odette; Bäumer, Tobias; Thomalla, Götz; Roessner, Veit; Haggard, Patrick; Münchau, Alexander; Kühn, Simone.
In: NEUROPSYCHOLOGIA, Vol. 65, 01.12.2014, p. 297-301.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - The neural correlates of tic inhibition in Gilles de la Tourette syndrome
AU - Ganos, Christos
AU - Kahl, Ursula
AU - Brandt, Valerie
AU - Schunke, Odette
AU - Bäumer, Tobias
AU - Thomalla, Götz
AU - Roessner, Veit
AU - Haggard, Patrick
AU - Münchau, Alexander
AU - Kühn, Simone
N1 - Copyright © 2014 Elsevier Ltd. All rights reserved.
PY - 2014/12/1
Y1 - 2014/12/1
N2 - Tics in Gilles de la Tourette syndrome (GTS) resemble fragments of normal motor behaviour but appear in an intrusive, repetitive and context-inappropriate manner. Although tics can be voluntarily inhibited on demand, the neural correlates of this process remain unclear. 14 GTS adults without relevant comorbidities participated in this study. First, tic severity and voluntary tic inhibitory capacity were evaluated outside the scanner. Second, patients were examined with resting state functional magnetic resonance imaging (RS-fMRI) in two states, free ticcing and voluntary tic inhibition. Local synchronization of spontaneous fMRI-signal was analysed with regional homogeneity (ReHo) and differences between both states (free ticcing
AB - Tics in Gilles de la Tourette syndrome (GTS) resemble fragments of normal motor behaviour but appear in an intrusive, repetitive and context-inappropriate manner. Although tics can be voluntarily inhibited on demand, the neural correlates of this process remain unclear. 14 GTS adults without relevant comorbidities participated in this study. First, tic severity and voluntary tic inhibitory capacity were evaluated outside the scanner. Second, patients were examined with resting state functional magnetic resonance imaging (RS-fMRI) in two states, free ticcing and voluntary tic inhibition. Local synchronization of spontaneous fMRI-signal was analysed with regional homogeneity (ReHo) and differences between both states (free ticcing
U2 - 10.1016/j.neuropsychologia.2014.08.007
DO - 10.1016/j.neuropsychologia.2014.08.007
M3 - SCORING: Journal article
C2 - 25128587
VL - 65
SP - 297
EP - 301
JO - NEUROPSYCHOLOGIA
JF - NEUROPSYCHOLOGIA
SN - 0028-3932
ER -