The neonatal window of opportunity-early priming for life

Standard

The neonatal window of opportunity-early priming for life. / Renz, Harald; Adkins, Becky D; Bartfeld, Sina; Blumberg, Richard S; Farber, Donna L; Garssen, Johan; Ghazal, Peter; Hackam, David J; Marsland, Benjamin J; McCoy, Kathy D; Penders, John; Prinz, Immo; Verhasselt, Valerie; von Mutius, Erika; Weiser, Jeffrey N; Wesemann, Duane R; Hornef, Mathias W.

In: J ALLERGY CLIN IMMUN, Vol. 141, No. 4, 04.2018, p. 1212-1214.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

Harvard

Renz, H, Adkins, BD, Bartfeld, S, Blumberg, RS, Farber, DL, Garssen, J, Ghazal, P, Hackam, DJ, Marsland, BJ, McCoy, KD, Penders, J, Prinz, I, Verhasselt, V, von Mutius, E, Weiser, JN, Wesemann, DR & Hornef, MW 2018, 'The neonatal window of opportunity-early priming for life', J ALLERGY CLIN IMMUN, vol. 141, no. 4, pp. 1212-1214. https://doi.org/10.1016/j.jaci.2017.11.019

APA

Renz, H., Adkins, B. D., Bartfeld, S., Blumberg, R. S., Farber, D. L., Garssen, J., Ghazal, P., Hackam, D. J., Marsland, B. J., McCoy, K. D., Penders, J., Prinz, I., Verhasselt, V., von Mutius, E., Weiser, J. N., Wesemann, D. R., & Hornef, M. W. (2018). The neonatal window of opportunity-early priming for life. J ALLERGY CLIN IMMUN, 141(4), 1212-1214. https://doi.org/10.1016/j.jaci.2017.11.019

Vancouver

Renz H, Adkins BD, Bartfeld S, Blumberg RS, Farber DL, Garssen J et al. The neonatal window of opportunity-early priming for life. J ALLERGY CLIN IMMUN. 2018 Apr;141(4):1212-1214. https://doi.org/10.1016/j.jaci.2017.11.019

Bibtex

@article{a9e6fc40f5f3444c9fb8dd087b8a2134,
title = "The neonatal window of opportunity-early priming for life",
abstract = "The concept of the neonatal window of opportunity assigns the early postnatal period a critical role for lifelong host-microbial and immune homeostasis. It is supported by epidemiological evidence that links postnatal environmental exposure with disease susceptibility and mechanisms in the neonate host that facilitate the postnatal transposition, establish a stable microbiome, and promote immune maturation. During the conference on “The neonatal window of opportunity – early priming for life,” postnatal micro-biome and immune maturation, epidemiological evidence, and fundamental mechanisms were discussed to identify new targets for future preventive and interventional measures.From December 5 to 7, 2016, the Herrenhausen Conference “The neonatal window of opportunity – early priming for life” took place at Hannover, Germany, sponsored by the Volkswagen Foundation. The concept of the “neonatal window of opportunity,” that is, a critical nonredundant time frame in a newborn{\textquoteright}s life during which environmental factors drive immune and tissue maturation and influence the susceptibility to immune-mediated and other diseases in adult life, was discussed.",
keywords = "Child Development/physiology, Environmental Exposure, Homeostasis, Host Microbial Interactions/immunology, Humans, Hypersensitivity/immunology, Immune System/growth & development, Immune Tolerance, Infant, Newborn, Microbiota, Risk Factors",
author = "Harald Renz and Adkins, {Becky D} and Sina Bartfeld and Blumberg, {Richard S} and Farber, {Donna L} and Johan Garssen and Peter Ghazal and Hackam, {David J} and Marsland, {Benjamin J} and McCoy, {Kathy D} and John Penders and Immo Prinz and Valerie Verhasselt and {von Mutius}, Erika and Weiser, {Jeffrey N} and Wesemann, {Duane R} and Hornef, {Mathias W}",
year = "2018",
month = apr,
doi = "10.1016/j.jaci.2017.11.019",
language = "English",
volume = "141",
pages = "1212--1214",
journal = "J ALLERGY CLIN IMMUN",
issn = "0091-6749",
publisher = "Mosby Inc.",
number = "4",

}

RIS

TY - JOUR

T1 - The neonatal window of opportunity-early priming for life

AU - Renz, Harald

AU - Adkins, Becky D

AU - Bartfeld, Sina

AU - Blumberg, Richard S

AU - Farber, Donna L

AU - Garssen, Johan

AU - Ghazal, Peter

AU - Hackam, David J

AU - Marsland, Benjamin J

AU - McCoy, Kathy D

AU - Penders, John

AU - Prinz, Immo

AU - Verhasselt, Valerie

AU - von Mutius, Erika

AU - Weiser, Jeffrey N

AU - Wesemann, Duane R

AU - Hornef, Mathias W

PY - 2018/4

Y1 - 2018/4

N2 - The concept of the neonatal window of opportunity assigns the early postnatal period a critical role for lifelong host-microbial and immune homeostasis. It is supported by epidemiological evidence that links postnatal environmental exposure with disease susceptibility and mechanisms in the neonate host that facilitate the postnatal transposition, establish a stable microbiome, and promote immune maturation. During the conference on “The neonatal window of opportunity – early priming for life,” postnatal micro-biome and immune maturation, epidemiological evidence, and fundamental mechanisms were discussed to identify new targets for future preventive and interventional measures.From December 5 to 7, 2016, the Herrenhausen Conference “The neonatal window of opportunity – early priming for life” took place at Hannover, Germany, sponsored by the Volkswagen Foundation. The concept of the “neonatal window of opportunity,” that is, a critical nonredundant time frame in a newborn’s life during which environmental factors drive immune and tissue maturation and influence the susceptibility to immune-mediated and other diseases in adult life, was discussed.

AB - The concept of the neonatal window of opportunity assigns the early postnatal period a critical role for lifelong host-microbial and immune homeostasis. It is supported by epidemiological evidence that links postnatal environmental exposure with disease susceptibility and mechanisms in the neonate host that facilitate the postnatal transposition, establish a stable microbiome, and promote immune maturation. During the conference on “The neonatal window of opportunity – early priming for life,” postnatal micro-biome and immune maturation, epidemiological evidence, and fundamental mechanisms were discussed to identify new targets for future preventive and interventional measures.From December 5 to 7, 2016, the Herrenhausen Conference “The neonatal window of opportunity – early priming for life” took place at Hannover, Germany, sponsored by the Volkswagen Foundation. The concept of the “neonatal window of opportunity,” that is, a critical nonredundant time frame in a newborn’s life during which environmental factors drive immune and tissue maturation and influence the susceptibility to immune-mediated and other diseases in adult life, was discussed.

KW - Child Development/physiology

KW - Environmental Exposure

KW - Homeostasis

KW - Host Microbial Interactions/immunology

KW - Humans

KW - Hypersensitivity/immunology

KW - Immune System/growth & development

KW - Immune Tolerance

KW - Infant, Newborn

KW - Microbiota

KW - Risk Factors

U2 - 10.1016/j.jaci.2017.11.019

DO - 10.1016/j.jaci.2017.11.019

M3 - SCORING: Journal article

C2 - 29247715

VL - 141

SP - 1212

EP - 1214

JO - J ALLERGY CLIN IMMUN

JF - J ALLERGY CLIN IMMUN

SN - 0091-6749

IS - 4

ER -