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The killer cell lectin-like receptor B1 (KLRB1) 503T>C polymorphism (rs1135816) and acute rejection after liver transplantation

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The killer cell lectin-like receptor B1 (KLRB1) 503T>C polymorphism (rs1135816) and acute rejection after liver transplantation. / Thude, H; Rother, S; Sterneck, M; Klempnauer, J; Nashan, B; Schwinzer, R; Koch, M.

In: HLA, Vol. 91, No. 1, 01.2018, p. 52-55.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Thude, H, Rother, S, Sterneck, M, Klempnauer, J, Nashan, B, Schwinzer, R & Koch, M 2018, 'The killer cell lectin-like receptor B1 (KLRB1) 503T>C polymorphism (rs1135816) and acute rejection after liver transplantation', HLA, vol. 91, no. 1, pp. 52-55. https://doi.org/10.1111/tan.13172

APA

Thude, H., Rother, S., Sterneck, M., Klempnauer, J., Nashan, B., Schwinzer, R., & Koch, M. (2018). The killer cell lectin-like receptor B1 (KLRB1) 503T>C polymorphism (rs1135816) and acute rejection after liver transplantation. HLA, 91(1), 52-55. https://doi.org/10.1111/tan.13172

Vancouver

Thude H, Rother S, Sterneck M, Klempnauer J, Nashan B, Schwinzer R et al. The killer cell lectin-like receptor B1 (KLRB1) 503T>C polymorphism (rs1135816) and acute rejection after liver transplantation. HLA. 2018 Jan;91(1):52-55. https://doi.org/10.1111/tan.13172

Bibtex

@article{c582f65fa4f94802807166a4dbb81692,
title = "The killer cell lectin-like receptor B1 (KLRB1) 503T>C polymorphism (rs1135816) and acute rejection after liver transplantation",
abstract = "The killer cell lectin-like receptor B1 (KLRB1) gene encodes for CD161 expressed by different subsets of leukocytes involved in the development of acute liver transplant rejection. The single nucleotide polymorphism (SNP) 503T>C (rs1135816) in the KLRB1 gene represents a missense mutation modifying functional properties of CD161. The aim of our study is to determine whether the SNP 503T>C is associated with acute liver transplant rejection. We genotyped the SNP for 163 liver recipients without acute rejection, 125 recipients with a single acute rejection, and 53 recipients with multiple acute rejections. The genotype frequencies within the groups did not show any significant difference. Our data suggest that the SNP 503T>C has no impact on the susceptibility of acute liver transplant rejection.",
keywords = "Journal Article",
author = "H Thude and S Rother and M Sterneck and J Klempnauer and B Nashan and R Schwinzer and M Koch",
note = "{\textcopyright} 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.",
year = "2018",
month = jan,
doi = "10.1111/tan.13172",
language = "English",
volume = "91",
pages = "52--55",
journal = "HLA",
issn = "2059-2302",
publisher = "Wiley-Blackwell",
number = "1",

}

RIS

TY - JOUR

T1 - The killer cell lectin-like receptor B1 (KLRB1) 503T>C polymorphism (rs1135816) and acute rejection after liver transplantation

AU - Thude, H

AU - Rother, S

AU - Sterneck, M

AU - Klempnauer, J

AU - Nashan, B

AU - Schwinzer, R

AU - Koch, M

N1 - © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

PY - 2018/1

Y1 - 2018/1

N2 - The killer cell lectin-like receptor B1 (KLRB1) gene encodes for CD161 expressed by different subsets of leukocytes involved in the development of acute liver transplant rejection. The single nucleotide polymorphism (SNP) 503T>C (rs1135816) in the KLRB1 gene represents a missense mutation modifying functional properties of CD161. The aim of our study is to determine whether the SNP 503T>C is associated with acute liver transplant rejection. We genotyped the SNP for 163 liver recipients without acute rejection, 125 recipients with a single acute rejection, and 53 recipients with multiple acute rejections. The genotype frequencies within the groups did not show any significant difference. Our data suggest that the SNP 503T>C has no impact on the susceptibility of acute liver transplant rejection.

AB - The killer cell lectin-like receptor B1 (KLRB1) gene encodes for CD161 expressed by different subsets of leukocytes involved in the development of acute liver transplant rejection. The single nucleotide polymorphism (SNP) 503T>C (rs1135816) in the KLRB1 gene represents a missense mutation modifying functional properties of CD161. The aim of our study is to determine whether the SNP 503T>C is associated with acute liver transplant rejection. We genotyped the SNP for 163 liver recipients without acute rejection, 125 recipients with a single acute rejection, and 53 recipients with multiple acute rejections. The genotype frequencies within the groups did not show any significant difference. Our data suggest that the SNP 503T>C has no impact on the susceptibility of acute liver transplant rejection.

KW - Journal Article

U2 - 10.1111/tan.13172

DO - 10.1111/tan.13172

M3 - SCORING: Journal article

C2 - 29111570

VL - 91

SP - 52

EP - 55

JO - HLA

JF - HLA

SN - 2059-2302

IS - 1

ER -