The influence of bisphosphonates on human osteoblast migration and integrin aVb3/tenascin C gene expression in vitro.
Standard
The influence of bisphosphonates on human osteoblast migration and integrin aVb3/tenascin C gene expression in vitro. / Koch, Felix P; Wunsch, Annette; Merkel, Christina; Ziebart, Thomas; Pabst, Andreas; Yekta, Sareh Said; Blessmann, Marco; Smeets, Ralf.
In: HEAD FACE MED, Vol. 7, No. 1, 1, 2011, p. 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - The influence of bisphosphonates on human osteoblast migration and integrin aVb3/tenascin C gene expression in vitro.
AU - Koch, Felix P
AU - Wunsch, Annette
AU - Merkel, Christina
AU - Ziebart, Thomas
AU - Pabst, Andreas
AU - Yekta, Sareh Said
AU - Blessmann, Marco
AU - Smeets, Ralf
PY - 2011
Y1 - 2011
N2 - Bisphosphonates are therapeutics of bone diseases, such as Paget's disease, multiple myeloma or osteoclastic metastases. As a severe side effect the bisphosphonate induced osteonecrosis of the jaw (BONJ) often requires surgical treatment and is accompanied with a disturbed wound healing.Therefore, the influence on adhesion and migration of human osteoblasts (hOB) after bisphosphonate therapy has been investigated by morphologic as well as gene expression methods.
AB - Bisphosphonates are therapeutics of bone diseases, such as Paget's disease, multiple myeloma or osteoclastic metastases. As a severe side effect the bisphosphonate induced osteonecrosis of the jaw (BONJ) often requires surgical treatment and is accompanied with a disturbed wound healing.Therefore, the influence on adhesion and migration of human osteoblasts (hOB) after bisphosphonate therapy has been investigated by morphologic as well as gene expression methods.
KW - Humans
KW - Cell Movement/drug effects/genetics
KW - Diphosphonates/pharmacology
KW - Gene Expression/drug effects
KW - Imidazoles/pharmacology
KW - Integrin alphaVbeta3/genetics
KW - Osteoblasts/drug effects
KW - Tenascin/genetics
KW - Humans
KW - Cell Movement/drug effects/genetics
KW - Diphosphonates/pharmacology
KW - Gene Expression/drug effects
KW - Imidazoles/pharmacology
KW - Integrin alphaVbeta3/genetics
KW - Osteoblasts/drug effects
KW - Tenascin/genetics
U2 - 10.1186/1746-160X-7-4
DO - 10.1186/1746-160X-7-4
M3 - SCORING: Journal article
VL - 7
SP - 4
JO - HEAD FACE MED
JF - HEAD FACE MED
SN - 1746-160X
IS - 1
M1 - 1
ER -