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The importance of placebo in headache research.

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The importance of placebo in headache research. / Diener, H-C; Schorn, C F; Bingel, Ulrike; Dodick, D W.

In: CEPHALALGIA, Vol. 28, No. 10, 10, 2008, p. 1003-1011.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Diener, H-C, Schorn, CF, Bingel, U & Dodick, DW 2008, 'The importance of placebo in headache research.', CEPHALALGIA, vol. 28, no. 10, 10, pp. 1003-1011. <http://www.ncbi.nlm.nih.gov/pubmed/18727647?dopt=Citation>

APA

Diener, H-C., Schorn, C. F., Bingel, U., & Dodick, D. W. (2008). The importance of placebo in headache research. CEPHALALGIA, 28(10), 1003-1011. [10]. http://www.ncbi.nlm.nih.gov/pubmed/18727647?dopt=Citation

Vancouver

Diener H-C, Schorn CF, Bingel U, Dodick DW. The importance of placebo in headache research. CEPHALALGIA. 2008;28(10):1003-1011. 10.

Bibtex

@article{f07d78fbd77441c7a28b255016ead979,
title = "The importance of placebo in headache research.",
abstract = "The best way to appreciate the efficacy of drug and behavioural therapy in the acute and prophylactic treatment of headache is to perform placebo-controlled randomized trials. In order to plan and conduct these studies in the most appropriate way, it is desirable to know which factors influence the placebo response. This paper reviews factors which influence the placebo response in clinical trials, such as expectation, blinding, route of application of drugs and age, gender and geographical distribution. Response rates of placebo in the treatment of acute headache episodes are higher than in headache prophylaxis. Invasive procedures such as injections have a higher placebo response compared with oral drugs. Variables known to influence the placebo response have to be taken into consideration to calculate properly the power of planned randomized trials.",
author = "H-C Diener and Schorn, {C F} and Ulrike Bingel and Dodick, {D W}",
year = "2008",
language = "Deutsch",
volume = "28",
pages = "1003--1011",
journal = "CEPHALALGIA",
issn = "0333-1024",
publisher = "SAGE Publications",
number = "10",

}

RIS

TY - JOUR

T1 - The importance of placebo in headache research.

AU - Diener, H-C

AU - Schorn, C F

AU - Bingel, Ulrike

AU - Dodick, D W

PY - 2008

Y1 - 2008

N2 - The best way to appreciate the efficacy of drug and behavioural therapy in the acute and prophylactic treatment of headache is to perform placebo-controlled randomized trials. In order to plan and conduct these studies in the most appropriate way, it is desirable to know which factors influence the placebo response. This paper reviews factors which influence the placebo response in clinical trials, such as expectation, blinding, route of application of drugs and age, gender and geographical distribution. Response rates of placebo in the treatment of acute headache episodes are higher than in headache prophylaxis. Invasive procedures such as injections have a higher placebo response compared with oral drugs. Variables known to influence the placebo response have to be taken into consideration to calculate properly the power of planned randomized trials.

AB - The best way to appreciate the efficacy of drug and behavioural therapy in the acute and prophylactic treatment of headache is to perform placebo-controlled randomized trials. In order to plan and conduct these studies in the most appropriate way, it is desirable to know which factors influence the placebo response. This paper reviews factors which influence the placebo response in clinical trials, such as expectation, blinding, route of application of drugs and age, gender and geographical distribution. Response rates of placebo in the treatment of acute headache episodes are higher than in headache prophylaxis. Invasive procedures such as injections have a higher placebo response compared with oral drugs. Variables known to influence the placebo response have to be taken into consideration to calculate properly the power of planned randomized trials.

M3 - SCORING: Zeitschriftenaufsatz

VL - 28

SP - 1003

EP - 1011

JO - CEPHALALGIA

JF - CEPHALALGIA

SN - 0333-1024

IS - 10

M1 - 10

ER -