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The impact of physical activity on serum levels of inflammatory markers in rheumatoid arthritis: A systematic literature review

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The impact of physical activity on serum levels of inflammatory markers in rheumatoid arthritis: A systematic literature review. / Burghardt, Rolf-Dieter; Kazim, Murteza Ali; Rüther, Wolfgang; Niemeier, Andreas; Strahl, André.

In: RHEUMATOL INT, Vol. 39, No. 5, 05.2019, p. 793-804.

Research output: SCORING: Contribution to journal › SCORING: Review article › Research

Harvard

Burghardt, R-D, Kazim, MA, Rüther, W, Niemeier, A & Strahl, A 2019, 'The impact of physical activity on serum levels of inflammatory markers in rheumatoid arthritis: A systematic literature review', RHEUMATOL INT, vol. 39, no. 5, pp. 793-804. https://doi.org/10.1007/s00296-019-04284-x

APA

Burghardt, R-D., Kazim, M. A., Rüther, W., Niemeier, A., & Strahl, A. (2019). The impact of physical activity on serum levels of inflammatory markers in rheumatoid arthritis: A systematic literature review. RHEUMATOL INT, 39(5), 793-804. https://doi.org/10.1007/s00296-019-04284-x

Vancouver

Burghardt R-D, Kazim MA, Rüther W, Niemeier A, Strahl A. The impact of physical activity on serum levels of inflammatory markers in rheumatoid arthritis: A systematic literature review. RHEUMATOL INT. 2019 May;39(5):793-804. https://doi.org/10.1007/s00296-019-04284-x

Bibtex

@article{9346abfd466442688245340d08014861,
title = "The impact of physical activity on serum levels of inflammatory markers in rheumatoid arthritis: A systematic literature review",
abstract = "This review aims to determine the specific effects of PA on systemic levels of interleukins and inflammatory markers. A systematic literature search was conducted in three computerized bibliographic databases (Medline, Embase, CENTRAL) to identify randomized controlled trials and matched case studies. Applied key words were: RA and PA including the terms exercise, exercise therapy, gymnastics and exercise movement techniques. Inclusion criteria were data on all types of proinflammatory interleukins (IL), C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR). For data synthesis, the populations, interventions and outcomes were described according to the PRISMA statement. A total of 1289 publications were found. Fifteen papers, related to 14 different study populations, met the inclusion criteria. No study revealed a significant change regarding IL or CRP levels in response to the intervention (PA). In three study populations, a significant reduction of the ESR was identified, but the effect from PA was not discernible from effects of changes of the anti-rheumatic medication in these studies. The strong variability in study designs, cohort size and types of physical training programs remains an obstacle in the assessment of the measurable effects of PA on inflammatory markers in patients with RA. At present, there is no sufficient evidence to conclude that PA has a significant impact on systemic levels of inflammatory markers in RA.",
keywords = "Journal Article, Review, Blood Sedimentation, Humans, Arthritis, Rheumatoid/immunology, Exercise/physiology, Exercise Therapy, C-Reactive Protein/immunology, Inflammation/immunology, Interleukins/immunology",
author = "Rolf-Dieter Burghardt and Kazim, {Murteza Ali} and Wolfgang R{\"u}ther and Andreas Niemeier and Andr{\'e} Strahl",
year = "2019",
month = may,
doi = "10.1007/s00296-019-04284-x",
language = "English",
volume = "39",
pages = "793--804",
journal = "RHEUMATOL INT",
issn = "0172-8172",
publisher = "Springer",
number = "5",

}

RIS

TY - JOUR

T1 - The impact of physical activity on serum levels of inflammatory markers in rheumatoid arthritis: A systematic literature review

AU - Burghardt, Rolf-Dieter

AU - Kazim, Murteza Ali

AU - Rüther, Wolfgang

AU - Niemeier, Andreas

AU - Strahl, André

PY - 2019/5

Y1 - 2019/5

N2 - This review aims to determine the specific effects of PA on systemic levels of interleukins and inflammatory markers. A systematic literature search was conducted in three computerized bibliographic databases (Medline, Embase, CENTRAL) to identify randomized controlled trials and matched case studies. Applied key words were: RA and PA including the terms exercise, exercise therapy, gymnastics and exercise movement techniques. Inclusion criteria were data on all types of proinflammatory interleukins (IL), C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR). For data synthesis, the populations, interventions and outcomes were described according to the PRISMA statement. A total of 1289 publications were found. Fifteen papers, related to 14 different study populations, met the inclusion criteria. No study revealed a significant change regarding IL or CRP levels in response to the intervention (PA). In three study populations, a significant reduction of the ESR was identified, but the effect from PA was not discernible from effects of changes of the anti-rheumatic medication in these studies. The strong variability in study designs, cohort size and types of physical training programs remains an obstacle in the assessment of the measurable effects of PA on inflammatory markers in patients with RA. At present, there is no sufficient evidence to conclude that PA has a significant impact on systemic levels of inflammatory markers in RA.

AB - This review aims to determine the specific effects of PA on systemic levels of interleukins and inflammatory markers. A systematic literature search was conducted in three computerized bibliographic databases (Medline, Embase, CENTRAL) to identify randomized controlled trials and matched case studies. Applied key words were: RA and PA including the terms exercise, exercise therapy, gymnastics and exercise movement techniques. Inclusion criteria were data on all types of proinflammatory interleukins (IL), C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR). For data synthesis, the populations, interventions and outcomes were described according to the PRISMA statement. A total of 1289 publications were found. Fifteen papers, related to 14 different study populations, met the inclusion criteria. No study revealed a significant change regarding IL or CRP levels in response to the intervention (PA). In three study populations, a significant reduction of the ESR was identified, but the effect from PA was not discernible from effects of changes of the anti-rheumatic medication in these studies. The strong variability in study designs, cohort size and types of physical training programs remains an obstacle in the assessment of the measurable effects of PA on inflammatory markers in patients with RA. At present, there is no sufficient evidence to conclude that PA has a significant impact on systemic levels of inflammatory markers in RA.

KW - Journal Article

KW - Review

KW - Blood Sedimentation

KW - Humans

KW - Arthritis, Rheumatoid/immunology

KW - Exercise/physiology

KW - Exercise Therapy

KW - C-Reactive Protein/immunology

KW - Inflammation/immunology

KW - Interleukins/immunology

U2 - 10.1007/s00296-019-04284-x

DO - 10.1007/s00296-019-04284-x

M3 - SCORING: Review article

C2 - 30899988

VL - 39

SP - 793

EP - 804

JO - RHEUMATOL INT

JF - RHEUMATOL INT

SN - 0172-8172

IS - 5

ER -